FR2396019A1 - Nouveaux glycopeptides acetyles hydrosolubles extraits de corps microbiens lyses de pseudomonas aeruginosa, procede de preparation et application a titre de medicaments - Google Patents
Nouveaux glycopeptides acetyles hydrosolubles extraits de corps microbiens lyses de pseudomonas aeruginosa, procede de preparation et application a titre de medicamentsInfo
- Publication number
- FR2396019A1 FR2396019A1 FR7720319A FR7720319A FR2396019A1 FR 2396019 A1 FR2396019 A1 FR 2396019A1 FR 7720319 A FR7720319 A FR 7720319A FR 7720319 A FR7720319 A FR 7720319A FR 2396019 A1 FR2396019 A1 FR 2396019A1
- Authority
- FR
- France
- Prior art keywords
- water soluble
- pseudomonas aeruginosa
- antiinflammatories
- prepn
- immunostimulant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000589517 Pseudomonas aeruginosa Species 0.000 title abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- -1 antibacterials Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- 229960001438 immunostimulant agent Drugs 0.000 title 1
- 239000003022 immunostimulating agent Substances 0.000 title 1
- 230000003308 immunostimulating effect Effects 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 2
- GMKMEZVLHJARHF-UHFFFAOYSA-N (2R,6R)-form-2.6-Diaminoheptanedioic acid Natural products OC(=O)C(N)CCCC(N)C(O)=O GMKMEZVLHJARHF-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 238000005852 acetolysis reaction Methods 0.000 abstract 1
- 238000011026 diafiltration Methods 0.000 abstract 1
- GMKMEZVLHJARHF-SYDPRGILSA-N meso-2,6-diaminopimelic acid Chemical compound [O-]C(=O)[C@@H]([NH3+])CCC[C@@H]([NH3+])C([O-])=O GMKMEZVLHJARHF-SYDPRGILSA-N 0.000 abstract 1
- 150000002772 monosaccharides Chemical class 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/104—Pseudomonadales, e.g. Pseudomonas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
Abstract
Nouveaux glycopeptides acétylés hydrosolubles extraits de corps microbiens lyses, caractérisés en ce que les microorganismes sont constitués par des Pseudomonas Aeruginosa, en ce que lesdits glycopeptides ont un poids moléculaire apparent compris entre 500 et 200 000, en ce qu'ils renferment au moins 20 % de substances à pouvoir biurétogène et au moins 25 % d'oses neutres, ne renferment pas d'acide diaminopimélique et présentent un maximum d'absorption dans l'Ultra-Violet à environ 210 m mu . Procédé de préparation et application à titre de médicaments de ces nouveaux glycopeptides.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7720319A FR2396019A1 (fr) | 1977-07-01 | 1977-07-01 | Nouveaux glycopeptides acetyles hydrosolubles extraits de corps microbiens lyses de pseudomonas aeruginosa, procede de preparation et application a titre de medicaments |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7720319A FR2396019A1 (fr) | 1977-07-01 | 1977-07-01 | Nouveaux glycopeptides acetyles hydrosolubles extraits de corps microbiens lyses de pseudomonas aeruginosa, procede de preparation et application a titre de medicaments |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2396019A1 true FR2396019A1 (fr) | 1979-01-26 |
FR2396019B1 FR2396019B1 (fr) | 1980-03-07 |
Family
ID=9192865
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7720319A Granted FR2396019A1 (fr) | 1977-07-01 | 1977-07-01 | Nouveaux glycopeptides acetyles hydrosolubles extraits de corps microbiens lyses de pseudomonas aeruginosa, procede de preparation et application a titre de medicaments |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2396019A1 (fr) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0012552A1 (fr) * | 1978-12-04 | 1980-06-25 | Merck & Co. Inc. | Hétéropolysaccharides produits par des bactéries et produits dérivés, leur préparation et la culture lyophylisée des bactéries |
US4326053A (en) * | 1978-12-04 | 1982-04-20 | Merck & Co., Inc. | Polysaccharide S-60 and bacterial fermentation process for its preparation |
US4326052A (en) * | 1978-12-04 | 1982-04-20 | Merck & Co., Inc. | Deacetylated polysaccharide S-60 |
US4377636A (en) * | 1979-06-08 | 1983-03-22 | Merck & Co., Inc. | Polysaccharide S-60 and bacterial fermentation process for its preparation |
US4385123A (en) * | 1979-06-08 | 1983-05-24 | Merck & Co., Inc. | Deacetylated polysaccharide S-60 |
FR2540136A1 (fr) * | 1983-01-28 | 1984-08-03 | Roussel Uclaf | Nouveau procede de preparation d'acylglycoproteines immunostimulantes extraites de klebsiella pneumoniae, compositions pharmaceutiques et procede de lutte contre les maladies allergiques |
EP0438747A1 (fr) * | 1989-12-22 | 1991-07-31 | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. | Composition stable d'antibiotiques glycopeptidiques |
US8143212B2 (en) | 2002-11-18 | 2012-03-27 | Vicuron Pharmaceuticals Inc. | Dalbavancin compositions for treatment of bacterial infections |
-
1977
- 1977-07-01 FR FR7720319A patent/FR2396019A1/fr active Granted
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0012552A1 (fr) * | 1978-12-04 | 1980-06-25 | Merck & Co. Inc. | Hétéropolysaccharides produits par des bactéries et produits dérivés, leur préparation et la culture lyophylisée des bactéries |
US4326053A (en) * | 1978-12-04 | 1982-04-20 | Merck & Co., Inc. | Polysaccharide S-60 and bacterial fermentation process for its preparation |
US4326052A (en) * | 1978-12-04 | 1982-04-20 | Merck & Co., Inc. | Deacetylated polysaccharide S-60 |
US4377636A (en) * | 1979-06-08 | 1983-03-22 | Merck & Co., Inc. | Polysaccharide S-60 and bacterial fermentation process for its preparation |
US4385123A (en) * | 1979-06-08 | 1983-05-24 | Merck & Co., Inc. | Deacetylated polysaccharide S-60 |
FR2540136A1 (fr) * | 1983-01-28 | 1984-08-03 | Roussel Uclaf | Nouveau procede de preparation d'acylglycoproteines immunostimulantes extraites de klebsiella pneumoniae, compositions pharmaceutiques et procede de lutte contre les maladies allergiques |
EP0115988A1 (fr) * | 1983-01-28 | 1984-08-15 | Roussel-Uclaf | Nouveau procédé de préparation d'acylglycoprotéines immunostimulantes extraites de Klebsiella pneumoniae, compositions pharmaceutiques antiallerqiques |
EP0438747A1 (fr) * | 1989-12-22 | 1991-07-31 | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. | Composition stable d'antibiotiques glycopeptidiques |
US8143212B2 (en) | 2002-11-18 | 2012-03-27 | Vicuron Pharmaceuticals Inc. | Dalbavancin compositions for treatment of bacterial infections |
Also Published As
Publication number | Publication date |
---|---|
FR2396019B1 (fr) | 1980-03-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |