KR960016889A - 뇌기능 개선제 - Google Patents

뇌기능 개선제 Download PDF

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Publication number
KR960016889A
KR960016889A KR1019950039253A KR19950039253A KR960016889A KR 960016889 A KR960016889 A KR 960016889A KR 1019950039253 A KR1019950039253 A KR 1019950039253A KR 19950039253 A KR19950039253 A KR 19950039253A KR 960016889 A KR960016889 A KR 960016889A
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KR
South Korea
Prior art keywords
lecithin
celine
fatty acid
phosphatidyl
acid ring
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KR1019950039253A
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English (en)
Inventor
마사시 사카이
히데유키 야마토야
나오미 미주사와
사토시 쿠도오
Original Assignee
쿠와하라 쥰
카부시키가이샤 야쿠르트혼샤
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17853809&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR960016889(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 쿠와하라 쥰, 카부시키가이샤 야쿠르트혼샤 filed Critical 쿠와하라 쥰
Publication of KR960016889A publication Critical patent/KR960016889A/ko

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

뇌내글루코오스의 농도를 증가시키는 현저한 작용을 나타내고, 그 투여를 받은 피검체의 뇌기능을 개선하는 효과를 가지는 뇌기능 개선제, 포스타티딜-L-셀린 또는 그 α위치 또는 β위치의 지방산고리를 절재해서 얻어지는 리소포스파티딜-L-셀린, 혹은 그들의 염을 유효성분으로서 함유한다.
이 포스타티딜-L-셀린은, 대두레시틴, 채종레시틴, 및 난황레시틴으로 이루어지는 군에서 선발된 적어도 1종의 원료레시틴에 유래하는 구성지방산고리를 보유한다.
포스타티딜-L-셀린은, 원료레시틴을 기질에 사용하여 포스파티딜기 전이반응을 이용해 제조된다.

Description

뇌기능 개선제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 포스타티딜-L-셀린 또는 그 염을 유효성분에 함유하고, 상기한 포스파티딜-L-셀린은, 대두레시틴, 채종레시틴 및 난황레시틴으로 이루어지는 군에서 선발된 적어도 1종의 원료레시틴에 유래하는 구성지방산고리를 가지고 있는 것을 특징으로 하는 뇌기능 개선제.
  2. 포스타티딜-L-셀린 또는 그 염을 유효성분에 함유하고, 상기한 포스파티딜-L-셀린은, 대두레시틴, 채종레시틴 및 난황레시틴으로 이루어지는 군에서 선발된 적어도 1종의 원료레시틴에 유래하는 구성지방산고리를 보유하고, 이 구성지방산고리는 수소첨가처리된 포화지방산고리인 것을 특징으로 하는 뇌기능 개선제.
  3. 리소포스파타딜-L-셀린 또는 그 염을 유효성분에 함유하고, 상기한 리소포스파타딜-L-셀린은, α위치 또는 β위치의 지방산고리가 절제된 포스파티딜-L-셀린으로 이루어지고, 상기한 포스파티딜-L-셀린 은 대두레시틴, 채종레시틴 및 난황레시틴으로 이루어지는 군에서 선발된 적어도 1종의 원료레시틴에 유래하는 구성지방산고리를 가지고 있는 것을 특징으로 하는 뇌기능 개선제.
  4. 리소포스파타딜-L-셀린 또는 그 염을 유효성분에 함유하고, 상기한 리소포스파타딜-L-셀린은, α위치 또는 β위치의 지방산고리가 절제된 포스파티딜-L-셀린으로 부터 나고, 상기 포스파티딜-L-셀린은 대두레시틴, 채종레시틴 및 난황레시틴으로 이루어지는 군에서 선발된 적어도 1종의 원료레시틴에 유래하는 구성지방산고리를 보유하고, 이 구성지방산고리를 수소첨가처리된 포화지방산고리인 것을 특징으로 하는 뇌기능 개선제.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950039253A 1994-11-08 1995-11-01 뇌기능 개선제 KR960016889A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6297998A JP3053537B2 (ja) 1994-11-08 1994-11-08 脳機能改善剤
JP94-297998 1994-11-08

Publications (1)

Publication Number Publication Date
KR960016889A true KR960016889A (ko) 1996-06-17

Family

ID=17853809

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950039253A KR960016889A (ko) 1994-11-08 1995-11-01 뇌기능 개선제

Country Status (7)

Country Link
US (2) US5900409A (ko)
EP (1) EP0711559B1 (ko)
JP (1) JP3053537B2 (ko)
KR (1) KR960016889A (ko)
CA (1) CA2162232C (ko)
DE (1) DE69534002T2 (ko)
ES (1) ES2237756T3 (ko)

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* Cited by examiner, † Cited by third party
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US7226916B1 (en) 2000-05-08 2007-06-05 N.V. Nutricia Preparation for the prevention and/or treatment of vascular disorders
JP4298902B2 (ja) 2000-08-09 2009-07-22 株式会社ヤクルト本社 リン脂質の製造法
US6733797B1 (en) 2000-11-15 2004-05-11 William K. Summers Neuroceutical for improving memory and cognitive abilities
US6896776B2 (en) 2000-12-18 2005-05-24 Applied Materials Inc. Method and apparatus for electro-chemical processing
US6635456B2 (en) 2001-02-09 2003-10-21 Fidia Farmaceutici S.P.A. Procedure for the preparation of pure phosphatides with phospholipase D
US7160432B2 (en) * 2001-03-14 2007-01-09 Applied Materials, Inc. Method and composition for polishing a substrate
US6899804B2 (en) 2001-12-21 2005-05-31 Applied Materials, Inc. Electrolyte composition and treatment for electrolytic chemical mechanical polishing
US7232514B2 (en) * 2001-03-14 2007-06-19 Applied Materials, Inc. Method and composition for polishing a substrate
US7323416B2 (en) 2001-03-14 2008-01-29 Applied Materials, Inc. Method and composition for polishing a substrate
US7128825B2 (en) 2001-03-14 2006-10-31 Applied Materials, Inc. Method and composition for polishing a substrate
US6811680B2 (en) 2001-03-14 2004-11-02 Applied Materials Inc. Planarization of substrates using electrochemical mechanical polishing
US7582564B2 (en) 2001-03-14 2009-09-01 Applied Materials, Inc. Process and composition for conductive material removal by electrochemical mechanical polishing
ES2227479T3 (es) * 2001-03-26 2005-04-01 Giventis Gmbh Alimento destinado a aumentar la capacidad cognitiva.
WO2003003981A2 (en) * 2001-07-05 2003-01-16 Vital Basics, Inc. Compositions for improving mental performance
CN1625406A (zh) * 2001-08-09 2005-06-08 底古萨食品配料有限公司 用于预防和治疗温血动物的应激状态的含有溶血磷脂酰丝氨酸的制剂
IL150240A (en) * 2002-06-16 2005-07-25 Lipogen Ltd Infant formula supplemented with phospholipids
US20050129738A1 (en) * 2002-06-16 2005-06-16 Lipogen Ltd. Infant formula supplemented with phospholipids
US6878532B1 (en) 2003-04-28 2005-04-12 Sioux Biochemical, Inc. Method of producing phosphatidylserine
US7390429B2 (en) 2003-06-06 2008-06-24 Applied Materials, Inc. Method and composition for electrochemical mechanical polishing processing
DE10340740A1 (de) * 2003-09-04 2005-03-31 Degussa Food Ingredients Gmbh Physiologisch aktive Zusammensetzung auf Phosphatidylserin-Basis
US7935365B2 (en) * 2003-10-22 2011-05-03 Enzymotec, Ltd. Glycerophospholipids for the improvement of cognitive functions
US7390744B2 (en) 2004-01-29 2008-06-24 Applied Materials, Inc. Method and composition for polishing a substrate
DE102005003865A1 (de) * 2005-01-27 2007-05-10 Bioghurt Biogarde Gmbh & Co. Kg Phosphatidylserin-basierte Zusammensetzung zur Steigerung der Gehirnfunktion
ITPD20050164A1 (it) 2005-05-30 2006-11-30 Fidia Farmaceutici Processo per la preparazione e l'isolamento di fosfatidi
US20070151866A1 (en) * 2006-01-05 2007-07-05 Applied Materials, Inc. Substrate polishing with surface pretreatment
JP6831558B2 (ja) * 2016-08-23 2021-02-17 株式会社Hbcフナト 脳機能改善組成物
CN112566633A (zh) * 2018-06-08 2021-03-26 民族医学研究所 增强中枢神经系统中葡萄糖水平的方法

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US4385053A (en) * 1981-03-11 1983-05-24 Barry Reisberg Treatment for human memory impairment associated with aging
JPS63245684A (ja) 1987-03-31 1988-10-12 Japanese Res & Dev Assoc Bio Reactor Syst Food Ind ホスフアチジン酸誘導体の製造法
JPS63245685A (ja) * 1987-03-31 1988-10-12 Japanese Res & Dev Assoc Bio Reactor Syst Food Ind リン脂質にホスホリパーゼを作用させる方法
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Also Published As

Publication number Publication date
EP0711559A2 (en) 1996-05-15
US5900409A (en) 1999-05-04
DE69534002D1 (de) 2005-03-17
US6117853A (en) 2000-09-12
JPH08133984A (ja) 1996-05-28
DE69534002T2 (de) 2006-01-12
ES2237756T3 (es) 2005-08-01
EP0711559B1 (en) 2005-02-09
JP3053537B2 (ja) 2000-06-19
EP0711559A3 (en) 1997-01-15
CA2162232C (en) 2007-05-22
CA2162232A1 (en) 1996-05-09

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