KR960005139B1 - 난용성 활성 성분을 위한 치료 시스템 - Google Patents
난용성 활성 성분을 위한 치료 시스템 Download PDFInfo
- Publication number
- KR960005139B1 KR960005139B1 KR1019880000168A KR880000168A KR960005139B1 KR 960005139 B1 KR960005139 B1 KR 960005139B1 KR 1019880000168 A KR1019880000168 A KR 1019880000168A KR 880000168 A KR880000168 A KR 880000168A KR 960005139 B1 KR960005139 B1 KR 960005139B1
- Authority
- KR
- South Korea
- Prior art keywords
- active ingredient
- water
- core
- casing
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH116/87-7 | 1987-01-14 | ||
| CH11687 | 1987-01-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR880008800A KR880008800A (ko) | 1988-09-13 |
| KR960005139B1 true KR960005139B1 (ko) | 1996-04-22 |
Family
ID=4179612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019880000168A Expired - Fee Related KR960005139B1 (ko) | 1987-01-14 | 1988-01-13 | 난용성 활성 성분을 위한 치료 시스템 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4992278A (https=) |
| EP (1) | EP0277092B1 (https=) |
| JP (1) | JP2656933B2 (https=) |
| KR (1) | KR960005139B1 (https=) |
| AT (1) | ATE72111T1 (https=) |
| AU (1) | AU604825B2 (https=) |
| CA (1) | CA1328403C (https=) |
| DE (1) | DE3868077D1 (https=) |
| DK (1) | DK13688A (https=) |
| ES (1) | ES2039287T3 (https=) |
| FI (1) | FI92648C (https=) |
| GR (1) | GR3003734T3 (https=) |
| IE (1) | IE61821B1 (https=) |
| IL (1) | IL85060A (https=) |
| MX (1) | MX10086A (https=) |
| MY (1) | MY102660A (https=) |
| NO (1) | NO175564C (https=) |
| NZ (1) | NZ223164A (https=) |
| PH (1) | PH25901A (https=) |
| PT (1) | PT86536B (https=) |
| ZA (1) | ZA88211B (https=) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1331563C (en) * | 1987-08-03 | 1994-08-23 | Gaylen M. Zentner | Device for the controlled release of drugs with donnan-like modulation by charged insoluble resins |
| US5030452A (en) * | 1989-01-12 | 1991-07-09 | Pfizer Inc. | Dispensing devices powered by lyotropic liquid crystals |
| US5108756A (en) * | 1989-01-12 | 1992-04-28 | Pfizer Inc. | Dispensing devices powered by lyotropic liquid crystals |
| DE3932987A1 (de) * | 1989-10-03 | 1991-04-11 | Int Pharma Agentur | System fuer die kontrollierte freisetzung von wirkstoffen und verfahren zu seiner herstellung |
| DD295760A5 (de) * | 1989-01-31 | 1991-11-14 | Martin-Luther-Universitaet Halle Wittenberg,De | Arzneistoffreigabesystem mit kotrollierter wirkstoffreisetzung |
| EP0408496A3 (en) * | 1989-07-12 | 1992-07-01 | Ciba-Geigy Ag | Solid dosage form for pharmaceutical substances |
| US5120548A (en) * | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5221536A (en) | 1990-05-07 | 1993-06-22 | Alza Corporation | Dosage form indicated for the management of abnormal posture, tremor and involuntary movement |
| US5192550A (en) * | 1990-05-07 | 1993-03-09 | Alza Corporation | Dosage form for treating central nervous system disorders |
| US5326570A (en) * | 1991-07-23 | 1994-07-05 | Pharmavene, Inc. | Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine |
| US5327977A (en) * | 1992-12-14 | 1994-07-12 | Anthony Lukashuk | Weeder with hollow tines |
| US6818229B1 (en) | 1993-09-20 | 2004-11-16 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia |
| US6080428A (en) | 1993-09-20 | 2000-06-27 | Bova; David J. | Nicotinic acid compositions for treating hyperlipidemia and related methods therefor |
| US20060263428A1 (en) * | 1993-09-20 | 2006-11-23 | Eugenio Cefali | Methods for treating hyperlipidemia with intermediate release nicotinic acid compositions having unique biopharmaceutical characteristics |
| US6746691B2 (en) | 1993-09-20 | 2004-06-08 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics |
| US6129930A (en) | 1993-09-20 | 2000-10-10 | Bova; David J. | Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night |
| US6676967B1 (en) * | 1993-09-20 | 2004-01-13 | Kos Pharmaceuticals, Inc. | Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia |
| ZA953078B (en) * | 1994-04-28 | 1996-01-05 | Alza Corp | Effective therapy for epilepsies |
| US6348469B1 (en) | 1995-04-14 | 2002-02-19 | Pharma Pass Llc | Solid compositions containing glipizide and polyethylene oxide |
| US5654005A (en) * | 1995-06-07 | 1997-08-05 | Andrx Pharmaceuticals, Inc. | Controlled release formulation having a preformed passageway |
| DE19531684A1 (de) * | 1995-08-29 | 1997-03-06 | Bayer Ag | Verfahren zur Herstellung von Arzneimittelzubereitungen mit kontrollierter Freisetzung |
| US6361796B1 (en) | 1996-10-25 | 2002-03-26 | Shire Laboratories, Inc. | Soluble form osmotic dose delivery system |
| DE69735002T2 (de) * | 1996-10-25 | 2006-10-26 | Shire Laboratories, Inc. | Osmotisches Verabreichungssystem für lösliche Dosen |
| JP2001517625A (ja) | 1997-09-25 | 2001-10-09 | バイエル・アクチエンゲゼルシヤフト | 活性成分放出制御薬物製剤 |
| DE19747261A1 (de) * | 1997-10-25 | 1999-04-29 | Bayer Ag | Osmotisches Arzneimittelfreisetzungssystem |
| HUP9902351A3 (en) * | 1998-07-22 | 2001-01-29 | Pharma Pass L L C Irvine | Solid compositions containing metoprolol and process for producing the same |
| US6706283B1 (en) * | 1999-02-10 | 2004-03-16 | Pfizer Inc | Controlled release by extrusion of solid amorphous dispersions of drugs |
| KR100647901B1 (ko) * | 1999-07-09 | 2006-11-17 | 보령제약 주식회사 | 세파클러-함유 서방성 약제조성물 및 그의 제조방법 |
| EP1967185A1 (en) * | 1999-12-23 | 2008-09-10 | Pfizer Products Inc. | Hydrogel-driven drug dosage form |
| JP2003518487A (ja) | 1999-12-23 | 2003-06-10 | ファイザー・プロダクツ・インク | ヒドロゲル駆動型積層薬物製剤 |
| AU5459201A (en) * | 2000-05-30 | 2001-12-11 | Add Advanced Drug Delivery Technologies Ag | Peroral therapeutic system comprising glipizide |
| IN190699B (https=) | 2001-02-02 | 2003-08-16 | Sun Pharmaceutical Ind Ltd | |
| GB0209265D0 (en) * | 2002-04-23 | 2002-06-05 | Novartis Ag | Organic compounds |
| EA200401462A1 (ru) * | 2002-05-06 | 2005-06-30 | Рэнбакси Лабораториз Лимитед | Однокамерная система осмотически регулируемой доставки лекарственного средства |
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| EP1592406A2 (en) * | 2003-02-13 | 2005-11-09 | Phares Pharmaceutical Research N.V. | Lipophilic compositions |
| US8075872B2 (en) * | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
| DE102004032051A1 (de) * | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
| DE102005005446A1 (de) * | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| EP1658054B1 (de) * | 2003-08-06 | 2007-06-27 | Grünenthal GmbH | Gegen missbrauch gesicherte darreichungsform |
| DE102004020220A1 (de) * | 2004-04-22 | 2005-11-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
| US20070048228A1 (en) * | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| DE10336400A1 (de) * | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| US7611728B2 (en) * | 2003-09-05 | 2009-11-03 | Supernus Pharmaceuticals, Inc. | Osmotic delivery of therapeutic compounds by solubility enhancement |
| DE102004023069A1 (de) | 2004-05-11 | 2005-12-08 | Bayer Healthcare Ag | Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil |
| DE102004032103A1 (de) * | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| DE102004032049A1 (de) * | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| AR053986A1 (es) | 2004-12-03 | 2007-05-30 | Osmotica Pharmaceutical Argent | Dispositivo osmotico que contiene amantadina y una sal osmotica |
| DE102005005449A1 (de) * | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| EP1690540A1 (en) * | 2005-02-15 | 2006-08-16 | Neuro3D | Composition comprising ocaperidone |
| US8858993B2 (en) | 2005-07-25 | 2014-10-14 | Metrics, Inc. | Coated tablet with zero-order or near zero-order release kinetics |
| US8778395B2 (en) | 2005-08-11 | 2014-07-15 | Andrx Labs, Llc | Diltiazem controlled release formulation and method of manufacture |
| US20070128281A1 (en) * | 2005-12-02 | 2007-06-07 | Patel Hasmukh B | Oral osmotic drug delivery system |
| US20070128280A1 (en) * | 2005-12-02 | 2007-06-07 | Patel Hasmukh B | Oral osmotic drug delivery system |
| US20070128283A1 (en) * | 2005-12-02 | 2007-06-07 | Patel Hasmukh B | Oral osmotic drug delivery system |
| US20070128282A1 (en) * | 2005-12-02 | 2007-06-07 | Patel Hasmukh B | Oral osmotic drug delivery system |
| US8747897B2 (en) | 2006-04-27 | 2014-06-10 | Supernus Pharmaceuticals, Inc. | Osmotic drug delivery system |
| US7714201B2 (en) * | 2006-12-22 | 2010-05-11 | Monsanto Technology Llc | Cotton variety 781000G |
| US7419684B2 (en) * | 2006-12-22 | 2008-09-02 | Reliant Pharmaceuticals, Inc. | System and method for manufacturing oral osmotic drug delivery devices, and methods of administering same |
| DE102007011485A1 (de) * | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
| CA2713128C (en) | 2008-01-25 | 2016-04-05 | Gruenenthal Gmbh | Pharmaceutical dosage form |
| AU2009243681B2 (en) * | 2008-05-09 | 2013-12-19 | Grunenthal Gmbh | Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step |
| CN102639118B (zh) | 2009-07-22 | 2015-07-29 | 格吕伦塔尔有限公司 | 氧化稳定的抗干扰剂型 |
| KR101738369B1 (ko) * | 2009-07-22 | 2017-05-22 | 그뤼넨탈 게엠베하 | 핫 멜트 압출된 제어 방출 투여형 |
| ES2606227T3 (es) * | 2010-02-03 | 2017-03-23 | Grünenthal GmbH | Preparación de una composición farmacéutica en polvo mediante una extrusora |
| BR112013005194A2 (pt) | 2010-09-02 | 2016-05-03 | Gruenenthal Gmbh | forma de dosagem resistente à violação compreendendo sal inorgânico |
| TWI516286B (zh) | 2010-09-02 | 2016-01-11 | 歌林達股份有限公司 | 含陰離子聚合物之抗破碎劑型 |
| DE102011007272A1 (de) | 2011-04-13 | 2012-10-18 | Bayer Pharma Aktiengesellschaft | Verzweigte 3-Phenylpropionsäure-Derivate und ihre Verwendung |
| BR112014001091A2 (pt) | 2011-07-29 | 2017-02-14 | Gruenenthal Gmbh | comprimido resistente à adulteração que fornece liberação imediata do fármaco |
| EA201400172A1 (ru) | 2011-07-29 | 2014-06-30 | Грюненталь Гмбх | Устойчивая к разрушению таблетка, которая обеспечивает немедленное высвобождение лекарственного средства |
| US20130143867A1 (en) | 2011-12-02 | 2013-06-06 | Sychroneuron Inc. | Acamprosate formulations, methods of using the same, and combinations comprising the same |
| MX356421B (es) | 2012-02-28 | 2018-05-29 | Gruenenthal Gmbh | Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico. |
| EP2838512B1 (en) | 2012-04-18 | 2018-08-22 | Grünenthal GmbH | Tamper resistant and dose-dumping resistant pharmaceutical dosage form |
| US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
| US9737490B2 (en) | 2013-05-29 | 2017-08-22 | Grünenthal GmbH | Tamper resistant dosage form with bimodal release profile |
| EP3003279A1 (en) | 2013-05-29 | 2016-04-13 | Grünenthal GmbH | Tamper-resistant dosage form containing one or more particles |
| WO2014197744A1 (en) | 2013-06-05 | 2014-12-11 | Synchroneuron, Inc. | Acamprosate formulations, methods of using the same, and combinations comprising the same |
| BR112016000194A8 (pt) | 2013-07-12 | 2019-12-31 | Gruenenthal Gmbh | forma de dosagem resistente à violação contendo o polímero de acetato de etileno-vinila |
| EP3073994A1 (en) | 2013-11-26 | 2016-10-05 | Grünenthal GmbH | Preparation of a powdery pharmaceutical composition by means of cryo-milling |
| WO2015173195A1 (en) | 2014-05-12 | 2015-11-19 | Grünenthal GmbH | Tamper resistant immediate release capsule formulation comprising tapentadol |
| EA201692388A1 (ru) | 2014-05-26 | 2017-05-31 | Грюненталь Гмбх | Лекарственная форма в виде множества частиц, защищенная от вызываемого этанолом сброса дозы |
| EP3258914A1 (en) | 2015-02-20 | 2017-12-27 | Osmotica Kereskedelmi ES Szolgaltato KFT | Controlled release oral dosage form of gaba receptor agonist |
| WO2016170097A1 (en) | 2015-04-24 | 2016-10-27 | Grünenthal GmbH | Tamper-resistant dosage form with immediate release and resistance against solvent extraction |
| JP2018526414A (ja) | 2015-09-10 | 2018-09-13 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 乱用抑止性の即放性製剤を用いた経口過剰摂取に対する保護 |
| UY38308A (es) | 2018-07-24 | 2020-02-28 | Bayer Pharma AG | Forma de dosificación farmacéutica administrable por vía oral con liberación modificada |
| CN112469398A (zh) | 2018-07-24 | 2021-03-09 | 拜耳公司 | 可口服给药并具有缓释作用的药物剂型 |
| US10905667B2 (en) | 2018-07-24 | 2021-02-02 | Bayer Pharma Aktiengesellschaft | Orally administrable modified-release pharmaceutical dosage form |
| CN118742293A (zh) * | 2022-01-31 | 2024-10-01 | 住友精化株式会社 | 药物控释制剂用组合物和药物控释制剂 |
| IL326413A (en) | 2023-08-08 | 2026-04-01 | United Therapeutics Corp | Method for producing an oral pharmaceutical osmotic system and a pharmaceutical batch produced using the same method |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4060598A (en) * | 1967-06-28 | 1977-11-29 | Boehringer Mannheim G.M.B.H. | Tablets coated with aqueous resin dispersions |
| US3845770A (en) * | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| DE2546577B2 (de) * | 1975-10-17 | 1981-04-02 | Sandoz-Patent-GmbH, 7850 Lörrach | Feste Stoffe aus Polyvinylpyrrolidon und Ergotalkaloiden |
| US4111202A (en) * | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system for the controlled and delivery of agent over time |
| US4327725A (en) * | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
| GB2150830B (en) * | 1983-12-05 | 1987-08-19 | Alza Corp | Drug dispenser |
| US4692336A (en) * | 1984-03-19 | 1987-09-08 | Alza Corporation | Self controlled release device for administering beneficial agent to recipient |
| US4685918A (en) * | 1985-02-01 | 1987-08-11 | Merck & Co., Inc. | Lipid osmotic pump |
| US4624847A (en) * | 1985-04-22 | 1986-11-25 | Alza Corporation | Drug delivery device for programmed delivery of beneficial drug |
| CH668187A5 (de) * | 1986-08-07 | 1988-12-15 | Ciba Geigy Ag | Therapeutisches system mit systemischer wirkung. |
-
1988
- 1988-01-08 EP EP88810005A patent/EP0277092B1/de not_active Expired - Lifetime
- 1988-01-08 DE DE8888810005T patent/DE3868077D1/de not_active Expired - Lifetime
- 1988-01-08 AT AT88810005T patent/ATE72111T1/de not_active IP Right Cessation
- 1988-01-08 ES ES198888810005T patent/ES2039287T3/es not_active Expired - Lifetime
- 1988-01-11 FI FI880100A patent/FI92648C/fi not_active IP Right Cessation
- 1988-01-11 IL IL85060A patent/IL85060A/xx not_active IP Right Cessation
- 1988-01-11 MY MYPI88000022A patent/MY102660A/en unknown
- 1988-01-11 PH PH36345A patent/PH25901A/en unknown
- 1988-01-12 NZ NZ223164A patent/NZ223164A/en unknown
- 1988-01-12 PT PT86536A patent/PT86536B/pt not_active IP Right Cessation
- 1988-01-12 CA CA000556272A patent/CA1328403C/en not_active Expired - Fee Related
- 1988-01-13 JP JP63003911A patent/JP2656933B2/ja not_active Expired - Lifetime
- 1988-01-13 ZA ZA88211A patent/ZA88211B/xx unknown
- 1988-01-13 DK DK013688A patent/DK13688A/da not_active Application Discontinuation
- 1988-01-13 AU AU10237/88A patent/AU604825B2/en not_active Ceased
- 1988-01-13 NO NO880124A patent/NO175564C/no unknown
- 1988-01-13 KR KR1019880000168A patent/KR960005139B1/ko not_active Expired - Fee Related
- 1988-01-13 IE IE8588A patent/IE61821B1/en not_active IP Right Cessation
- 1988-01-13 MX MX1008688A patent/MX10086A/es unknown
-
1989
- 1989-08-03 US US07/390,435 patent/US4992278A/en not_active Expired - Fee Related
-
1992
- 1992-02-06 GR GR910402099T patent/GR3003734T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2656933B2 (ja) | 1997-09-24 |
| MY102660A (en) | 1992-08-17 |
| AU1023788A (en) | 1988-07-21 |
| ZA88211B (en) | 1989-10-25 |
| EP0277092A1 (de) | 1988-08-03 |
| FI92648B (fi) | 1994-09-15 |
| NO175564B (no) | 1994-07-25 |
| EP0277092B1 (de) | 1992-01-29 |
| DK13688A (da) | 1988-07-15 |
| GR3003734T3 (https=) | 1993-03-16 |
| ES2039287T3 (es) | 1993-09-16 |
| IL85060A0 (en) | 1988-06-30 |
| NO880124D0 (no) | 1988-01-13 |
| NZ223164A (en) | 1990-01-29 |
| IE61821B1 (en) | 1994-11-30 |
| FI880100L (fi) | 1988-07-15 |
| KR880008800A (ko) | 1988-09-13 |
| ATE72111T1 (de) | 1992-02-15 |
| DE3868077D1 (de) | 1992-03-12 |
| FI92648C (fi) | 1994-12-27 |
| JPS63174922A (ja) | 1988-07-19 |
| NO880124L (no) | 1988-07-15 |
| IL85060A (en) | 1992-01-15 |
| PH25901A (en) | 1991-12-19 |
| AU604825B2 (en) | 1991-01-03 |
| CA1328403C (en) | 1994-04-12 |
| DK13688D0 (da) | 1988-01-13 |
| MX10086A (es) | 1993-12-01 |
| IE880085L (en) | 1988-07-14 |
| PT86536A (pt) | 1989-01-30 |
| FI880100A0 (fi) | 1988-01-11 |
| US4992278A (en) | 1991-02-12 |
| NO175564C (no) | 1994-11-02 |
| PT86536B (pt) | 1994-02-28 |
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