KR940006321B1 - 수출후의 유착증 발생을 억제하기 위한 국소투여용 비-스테로이드성 소염제 함유 담체의 제조방법 - Google Patents

수출후의 유착증 발생을 억제하기 위한 국소투여용 비-스테로이드성 소염제 함유 담체의 제조방법 Download PDF

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Publication number
KR940006321B1
KR940006321B1 KR1019860010031A KR860010031A KR940006321B1 KR 940006321 B1 KR940006321 B1 KR 940006321B1 KR 1019860010031 A KR1019860010031 A KR 1019860010031A KR 860010031 A KR860010031 A KR 860010031A KR 940006321 B1 KR940006321 B1 KR 940006321B1
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KR
South Korea
Prior art keywords
ibuprofen
nsaid
microcapsules
vesicles
nsaids
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Expired - Lifetime
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KR1019860010031A
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English (en)
Korean (ko)
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KR870004703A (ko
Inventor
디. 쉬필드 워렌
비. 죤스 더글라스
더블류. 샐라비 샐라비
에스. 디저르가 저어
이 엘. 리춰 레로
Original Assignee
에티콘, 인코포레이티드
로버트 엘. 미니어
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Publication of KR870004703A publication Critical patent/KR870004703A/ko
Application granted granted Critical
Publication of KR940006321B1 publication Critical patent/KR940006321B1/ko
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dispersion Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1019860010031A 1985-11-27 1986-11-27 수출후의 유착증 발생을 억제하기 위한 국소투여용 비-스테로이드성 소염제 함유 담체의 제조방법 Expired - Lifetime KR940006321B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US80254585A 1985-11-27 1985-11-27
US802,545 1985-11-27
US802545 1985-11-27
US90012286A 1986-08-25 1986-08-25
US900122 1986-08-25
US900,122 1986-08-25

Publications (2)

Publication Number Publication Date
KR870004703A KR870004703A (ko) 1987-06-01
KR940006321B1 true KR940006321B1 (ko) 1994-07-16

Family

ID=27122463

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019860010031A Expired - Lifetime KR940006321B1 (ko) 1985-11-27 1986-11-27 수출후의 유착증 발생을 억제하기 위한 국소투여용 비-스테로이드성 소염제 함유 담체의 제조방법

Country Status (7)

Country Link
EP (1) EP0225162B1 (https=)
JP (1) JPH0798755B2 (https=)
KR (1) KR940006321B1 (https=)
AU (1) AU587299B2 (https=)
DE (1) DE3683606D1 (https=)
GR (1) GR3003915T3 (https=)
YU (1) YU46032B (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4877619A (en) * 1986-08-25 1989-10-31 Vestar, Inc. Liposomal vesicles for intraperitoneal administration of therapeutic agents
GB8701392D0 (en) * 1987-01-22 1987-02-25 Boots Co Plc Therapeutic agents
WO1991012026A1 (en) * 1990-02-14 1991-08-22 Macnaught Pty Limited Means of reducing surgical adhesions
ATE118168T1 (de) * 1990-12-03 1995-02-15 Vestar Inc Verhütung der synovialischen adhäsion.
US5583114A (en) 1994-07-27 1996-12-10 Minnesota Mining And Manufacturing Company Adhesive sealant composition
USRE38827E1 (en) 1994-07-27 2005-10-11 3M Innovative Properties Company Adhesive sealant composition
GR1003359B (el) * 1998-12-24 2000-04-10 �.�. ����������� �.�.�.�. Λιποσωμιακο νιφλουμικο οξυ - νεο διαδερμικο αντιφλεγμονωδες φαρμακο [κεφαλη ψαροτουφεκου
US7029700B2 (en) 2000-01-14 2006-04-18 Brown University Research Foundation Micronized freeze-dried particles
CA2397404C (en) * 2000-01-14 2008-12-02 Brown University Research Foundation Micronized freeze-dried particles
WO2004078210A1 (ja) 2003-03-06 2004-09-16 Takashi Muramatsu 開腹手術後の癒着の予防剤
US20050106230A1 (en) * 2003-11-17 2005-05-19 Young Janel E. Drug-enhanced adhesion prevention
US9066912B2 (en) * 2003-11-17 2015-06-30 Ethicon, Inc. Drug-enhanced adhesion prevention
DE102008005172A1 (de) * 2008-01-19 2009-07-23 Mike Ehrlich Pharmazeutische Zusammensetzung zur Verhinderung von post-operativen Adhäsionen
ES2330295B1 (es) * 2008-06-06 2010-09-23 Laboratorios Alcala Farma, Sl Formulacion topica de ibuprofeno.
US11007161B1 (en) 2014-12-31 2021-05-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films
US10561627B2 (en) 2014-12-31 2020-02-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films
US10596117B1 (en) 2014-12-31 2020-03-24 Eric Morrison Lipoleosomes as carriers for aromatic amide anesthetic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3755558A (en) * 1971-02-23 1973-08-28 Du Pont Polylactide drug mixtures for topical application atelet aggregation
GB1523965A (en) * 1976-03-19 1978-09-06 Ici Ltd Pharmaceutical compositions containing steroids
US4389330A (en) * 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
US4346108A (en) * 1981-06-22 1982-08-24 The Upjohn Manufacturing Company M Method for preventing adhesion formation
US4530840A (en) * 1982-07-29 1985-07-23 The Stolle Research And Development Corporation Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents

Also Published As

Publication number Publication date
YU46032B (sh) 1992-12-21
KR870004703A (ko) 1987-06-01
EP0225162A3 (en) 1987-11-19
DE3683606D1 (de) 1992-03-05
YU202886A (en) 1988-06-30
GR3003915T3 (https=) 1993-03-16
JPH0798755B2 (ja) 1995-10-25
AU587299B2 (en) 1989-08-10
EP0225162B1 (en) 1992-01-22
JPS62155223A (ja) 1987-07-10
AU6570986A (en) 1987-06-04
EP0225162A2 (en) 1987-06-10

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