KR930016439A - 시이엔피-비(cenp-b)항원 결정부 - Google Patents

시이엔피-비(cenp-b)항원 결정부 Download PDF

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KR930016439A
KR930016439A KR1019930000373A KR930000373A KR930016439A KR 930016439 A KR930016439 A KR 930016439A KR 1019930000373 A KR1019930000373 A KR 1019930000373A KR 930000373 A KR930000373 A KR 930000373A KR 930016439 A KR930016439 A KR 930016439A
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test solution
peptide
acid sequence
fragment
nucleic acid
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KR1019930000373A
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KR100296198B1 (ko
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로날드 베레이엔
왈테루스 자코부스 반 벤루이
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에프. 지. 엠. 헤르만스, 에이. 지. 제이. 베르미렌
악조 엔. 브이.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • General Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
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Abstract

본 발명은 항 동원체 자가 항체(anticentromere autoantibody:ACA)와 면역 화학적으로 반응성인 펩티드 또는 그 단편에 관한 것이다.
본 발명은 또한, 시험액중의 항 동원체 자가 항체의 검출 또는 동원체 항원의 검출방법과, 상기 방법이 적용되는 경우에 사용되는 면역화학적 시약 및 키트에 관한 것이다.

Description

시이엔피-비(CENP-B)항원 결정부
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 항동원체 자가 항체(anticentromere autoantibodies:ACA)와 면역 화학적으로 반응성인, 본 발명에 따른 60 아미노산 펩티드를 나타내는 1문자 암호로된 아미노산 서열도이다.

Claims (7)

  1. 항동원체 자가 항체(anticentromere autoantibodies)와 면역 화학적으로 반응성인 하기의 아미노산 서열을 갖는 펩티드, 또는 그 단편 또는 유사체, 또는 상기의 펩티드, 그 단편 또는 유사체로 구성되는 폴리펩티드:
  2. 제1항에 따른 펩티드, 그 단편 또는 유사체, 또는 폴리펩티드를 포함하는 면역 화학적 시약.
  3. 제2항에 따른 면역 화학적 시약을 시험액과 접촉시키고, 펩티드와 시험액 중의 항체 사이에 형성되는 면역복합체의 존재를 검출하여, 시험액중의 항동원체 자가 항체의 존재에 대한 지표로 삼는 것을 특징으로 하는 시험액중의 항 동원체 자가 항체의 검출방법.
  4. 제2항에 따른 면역화학적 시약을 시험액 및 항 동원체 자가 항체와 접촉시킨 다음, 시험액중의 동원체 항원의 존재에 대한 지표인 형성된 면역 복합체의 존재를 검출하는 것을 특징으로 하는 시험액중의 동원체 항원의 검출방법.
  5. 동원체 핵산 서열의 핵산 증폭을 수행하고 검출하기 위해서, 프라이머로서 제1항에 따른 아미노산 서열을 암호화하는 서열 또는 그 단편을 사용하는, 시험액중의 동원체 핵산 서열의 증폭 및 검출방법.
  6. 제3항 또는 제4항에 따른 면역 분석법을 수행하기 위한 시험 키트.
  7. 제5항에 따른 증폭방법을 수행하기 위한 증폭 시험 키트.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019930000373A 1992-01-13 1993-01-13 시이엔피-비(cenp-b)에피토프 KR100296198B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP91.200.0650 1992-01-13
EP91.200.0658 1992-01-13
EP92200065 1992-01-13

Publications (2)

Publication Number Publication Date
KR930016439A true KR930016439A (ko) 1993-08-26
KR100296198B1 KR100296198B1 (ko) 2001-10-22

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Country Link
EP (1) EP0552829B1 (ko)
JP (1) JPH05310790A (ko)
KR (1) KR100296198B1 (ko)
AT (1) ATE179183T1 (ko)
AU (1) AU664063B2 (ko)
CA (1) CA2087143A1 (ko)
DE (1) DE69324509T2 (ko)
DK (1) DK0552829T3 (ko)
ES (1) ES2132171T3 (ko)
FI (1) FI109704B (ko)
GR (1) GR3030727T3 (ko)
ZA (1) ZA93174B (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100693042B1 (ko) * 2004-11-10 2007-03-12 삼성전자주식회사 무선 전원 공급 장치 및 그 방법

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7227057B2 (en) 1997-06-03 2007-06-05 Chromatin, Inc. Plant centromere compositions
US7119250B2 (en) 1997-06-03 2006-10-10 The University Of Chicago Plant centromere compositions
US6900012B1 (en) 1997-06-03 2005-05-31 The University Of Chicago Plant artificial chromosome compositions and methods
US7235716B2 (en) 1997-06-03 2007-06-26 Chromatin, Inc. Plant centromere compositions
US7193128B2 (en) 1997-06-03 2007-03-20 Chromatin, Inc. Methods for generating or increasing revenues from crops
US6177254B1 (en) * 1998-12-15 2001-01-23 Jerome Bernard Rattner Nucleolus autoantigenic marker for systemic lupus erthyematosus
US7989202B1 (en) 1999-03-18 2011-08-02 The University Of Chicago Plant centromere compositions
US8729341B2 (en) 2004-02-23 2014-05-20 University Of Chicago Plants modified with mini-chromosomes
WO2007030510A2 (en) 2005-09-08 2007-03-15 Chromatin Inc. Plants modified with mini-chromosomes
US8614089B2 (en) 2007-03-15 2013-12-24 Chromatin, Inc. Centromere sequences and minichromosomes
CA2767724A1 (en) 2009-07-23 2011-01-27 Chromatin, Inc. Sorghum centromere sequences and minichromosomes
DE102009039705A1 (de) 2009-08-31 2011-04-07 Dr. Fooke Laboratorien Gmbh Peptide des CENP-A und ihre Verwendung
ES2395100B2 (es) * 2011-07-11 2013-09-13 Univ Cadiz Metodo de obtencion de datos utiles para el diagnostico diferencial de la esclerodermia.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5091303A (en) * 1989-10-27 1992-02-25 The General Hospital Corporation Diagnosis of wegener's granulomatosis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100693042B1 (ko) * 2004-11-10 2007-03-12 삼성전자주식회사 무선 전원 공급 장치 및 그 방법

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ATE179183T1 (de) 1999-05-15
EP0552829B1 (en) 1999-04-21
AU664063B2 (en) 1995-11-02
EP0552829A1 (en) 1993-07-28
FI930106A (fi) 1993-07-14
DK0552829T3 (da) 1999-10-25
FI930106A0 (fi) 1993-01-12
DE69324509T2 (de) 1999-10-07
CA2087143A1 (en) 1993-07-14
FI109704B (fi) 2002-09-30
GR3030727T3 (en) 1999-11-30
ZA93174B (en) 1993-08-13
DE69324509D1 (de) 1999-05-27
JPH05310790A (ja) 1993-11-22
KR100296198B1 (ko) 2001-10-22
ES2132171T3 (es) 1999-08-16
AU3114993A (en) 1993-07-15

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