KR930009445B1 - 신규 스테로이드 디올과 이들을 함유하는 약제학적 조성물 및 이들의 제조방법 - Google Patents

신규 스테로이드 디올과 이들을 함유하는 약제학적 조성물 및 이들의 제조방법 Download PDF

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Publication number
KR930009445B1
KR930009445B1 KR1019900003056A KR900003056A KR930009445B1 KR 930009445 B1 KR930009445 B1 KR 930009445B1 KR 1019900003056 A KR1019900003056 A KR 1019900003056A KR 900003056 A KR900003056 A KR 900003056A KR 930009445 B1 KR930009445 B1 KR 930009445B1
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KR
South Korea
Prior art keywords
dione
hydrogen
acetate
geunan
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1019900003056A
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English (en)
Korean (ko)
Other versions
KR900014422A (ko
Inventor
몰나르 싸바
하조스 기요르기
스쯔포르니 라스쯔로
로드 요세프
키라리 아르파드
부르 네 메쩨이 안나
쑈르게이 야노스
스쩨케리 크리스티나
호르가쓰 릴라
페게테 기요르기
헤레니 불쑤
홀리 산도르
스쭈뇨그 요세프
Original Assignee
리히터 게데온 베기에스제티 기아르 알. 티
에바 프리드만, 가보 게레브
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 리히터 게데온 베기에스제티 기아르 알. 티, 에바 프리드만, 가보 게레브 filed Critical 리히터 게데온 베기에스제티 기아르 알. 티
Publication of KR900014422A publication Critical patent/KR900014422A/ko
Application granted granted Critical
Publication of KR930009445B1 publication Critical patent/KR930009445B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0092—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by an OH group free esterified or etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019900003056A 1989-03-09 1990-03-08 신규 스테로이드 디올과 이들을 함유하는 약제학적 조성물 및 이들의 제조방법 Expired - Fee Related KR930009445B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU1156/89 1989-03-09
HU6602.89 1989-03-09
HU891156A HU203562B (en) 1989-03-09 1989-03-09 Process for producing new steroide diols and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
KR900014422A KR900014422A (ko) 1990-10-23
KR930009445B1 true KR930009445B1 (ko) 1993-10-04

Family

ID=10953088

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900003056A Expired - Fee Related KR930009445B1 (ko) 1989-03-09 1990-03-08 신규 스테로이드 디올과 이들을 함유하는 약제학적 조성물 및 이들의 제조방법

Country Status (17)

Country Link
US (1) US5082835A (https=)
EP (1) EP0387091A3 (https=)
JP (1) JPH06104679B2 (https=)
KR (1) KR930009445B1 (https=)
CN (1) CN1045396A (https=)
AR (1) AR244700A1 (https=)
AU (1) AU623503B2 (https=)
CA (1) CA2011282A1 (https=)
EG (1) EG19411A (https=)
FI (1) FI901199A7 (https=)
HU (1) HU203562B (https=)
IL (1) IL93478A (https=)
IN (1) IN170846B (https=)
NO (1) NO177147C (https=)
PH (1) PH26676A (https=)
PT (1) PT93375A (https=)
ZA (1) ZA901752B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
FR2675146A1 (fr) * 1991-04-10 1992-10-16 Roussel Uclaf Nouveaux derives sterouides de la pregna-1,4-diene-3,20-dione, leur preparation, leur application a la preparation de derives 16,17-methylene dioxy substitues et nouveaux intermediaires.
AU4093799A (en) 1998-05-22 1999-12-13 Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
CA2789262C (en) 2005-04-28 2016-10-04 Proteus Digital Health, Inc. Pharma-informatics system
EP1945240B1 (en) 2005-09-16 2016-12-28 Raptor Pharmaceutical Inc Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof
TR201908314T4 (tr) 2009-02-20 2019-06-21 2 Bbb Medicines B V Glutatyon bazlı ilaç dağıtım sistemi.
KR101909711B1 (ko) 2009-05-06 2018-12-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
CN110078785A (zh) * 2019-06-04 2019-08-02 博诺康源(北京)药业科技有限公司 一种布地奈德杂质ep-ze的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3167545A (en) * 1959-02-07 1965-01-26 Syntex Corp 16beta-methyl-16alpha, 17 alpha-dihydroxy pregnenes and the 16alpha, 17alpha-cyclic ketals and acetals thereof
US3345362A (en) * 1961-07-27 1967-10-03 Lilly Co Eli Novel pregnenolone acetonides
US4036831A (en) * 1975-10-28 1977-07-19 Steroid Development Company Establishment Trimethyl siloxane steroid intermediates
KR970000046B1 (ko) * 1987-08-14 1997-01-04 더 엎죤 캄파니 개선된 9α-탈할로겐화 방법

Also Published As

Publication number Publication date
CN1045396A (zh) 1990-09-19
CA2011282A1 (en) 1990-09-09
NO177147B (no) 1995-04-18
JPH06104679B2 (ja) 1994-12-21
EP0387091A3 (en) 1992-05-06
AU623503B2 (en) 1992-05-14
FI901199A7 (fi) 1990-09-10
AR244700A1 (es) 1993-11-30
NO901103L (no) 1990-09-10
PT93375A (pt) 1990-11-07
US5082835A (en) 1992-01-21
EG19411A (en) 1995-01-31
NO177147C (no) 1995-07-26
IL93478A0 (en) 1990-11-29
ZA901752B (en) 1991-05-29
PH26676A (en) 1992-09-15
HU203562B (en) 1991-08-28
IN170846B (https=) 1992-05-30
IL93478A (en) 1994-11-11
AU5110290A (en) 1990-09-13
NO901103D0 (no) 1990-03-08
EP0387091A2 (en) 1990-09-12
FI901199A0 (fi) 1990-03-09
KR900014422A (ko) 1990-10-23
JPH02279695A (ja) 1990-11-15

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