KR930007945A - 트리아자스피로데카논-메틸크로만 - Google Patents

트리아자스피로데카논-메틸크로만 Download PDF

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Publication number
KR930007945A
KR930007945A KR1019920019792A KR920019792A KR930007945A KR 930007945 A KR930007945 A KR 930007945A KR 1019920019792 A KR1019920019792 A KR 1019920019792A KR 920019792 A KR920019792 A KR 920019792A KR 930007945 A KR930007945 A KR 930007945A
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KR
South Korea
Prior art keywords
straight
carbon atoms
chain alkyl
branched chain
group
Prior art date
Application number
KR1019920019792A
Other languages
English (en)
Korean (ko)
Inventor
하이네 한스-게오르그
쇼헤-루프 루돌프
글라제르 토마스
마리 빅토르 데 프리 장
돔페르트 볼프강
조머마이어 헤닝
Original Assignee
권터 슈마허, 클라우스 데너
바이엘 악티 엔게젤 샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 권터 슈마허, 클라우스 데너, 바이엘 악티 엔게젤 샤프트 filed Critical 권터 슈마허, 클라우스 데너
Publication of KR930007945A publication Critical patent/KR930007945A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrane Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)
KR1019920019792A 1991-10-28 1992-10-27 트리아자스피로데카논-메틸크로만 KR930007945A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4135473A DE4135473A1 (de) 1991-10-28 1991-10-28 Triazaspirodecanon-methylchromane
DEP4135473.7 1991-10-28

Publications (1)

Publication Number Publication Date
KR930007945A true KR930007945A (ko) 1993-05-20

Family

ID=6443565

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920019792A KR930007945A (ko) 1991-10-28 1992-10-27 트리아자스피로데카논-메틸크로만

Country Status (19)

Country Link
US (1) US6060482A (de)
EP (1) EP0539803B1 (de)
JP (1) JP3257708B2 (de)
KR (1) KR930007945A (de)
AT (1) ATE175414T1 (de)
AU (1) AU650792B2 (de)
CA (1) CA2081256A1 (de)
CZ (1) CZ322492A3 (de)
DE (2) DE4135473A1 (de)
DK (1) DK0539803T3 (de)
ES (1) ES2125879T3 (de)
FI (1) FI924848A (de)
GR (1) GR3029450T3 (de)
HU (1) HUT64068A (de)
IL (1) IL103546A0 (de)
MX (1) MX9205869A (de)
NO (1) NO923974L (de)
TW (1) TW208010B (de)
ZA (1) ZA928290B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19522088A1 (de) * 1995-06-19 1997-01-02 Bayer Ag Benzisothiazolyl-substituierte Aminomethylchromane
CA2226058C (en) * 1997-01-30 2008-01-29 F. Hoffmann-La Roche Ag 8-substituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives
JP3989247B2 (ja) * 1999-12-06 2007-10-10 ユーロ−セルティーク エス．エイ． ノシセプチン受容体親和性を有するトリアゾスピロ化合物
JPWO2003040382A1 (ja) * 2001-11-09 2005-03-03 株式会社カネカ 光学活性クロマン誘導体の製造法および中間体
US6995168B2 (en) 2002-05-31 2006-02-07 Euro-Celtique S.A. Triazaspiro compounds useful for treating or preventing pain
WO2004022558A2 (en) * 2002-09-09 2004-03-18 Janssen Pharmaceutica, N.V. Hydroxy alkyl substituted 1,3,8-triazaspiro[4.5]decan-4-one derivatives useful for the treatment of orl-1 receptor mediated disorders
WO2005036104A1 (en) * 2003-10-16 2005-04-21 Collier William R Fluid level detector and alarm apparatus
US20060178390A1 (en) * 2004-08-02 2006-08-10 Alfonzo Jordan 1,3,8-Triazaspiro[4,5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders
CN103202840B (zh) * 2006-11-28 2015-02-11 詹森药业有限公司 3-(3-氨基-2-(r)-羟基-丙基)-1-(4-氟-苯基)-8-(8-甲基-萘-1-基甲基)-1,3,8-三氮杂-螺[4.5]癸烷-4-酮的盐
EP2150552B1 (de) * 2007-04-09 2013-01-02 Janssen Pharmaceutica NV 1,3,8-trisubstituierte-1,3,8-triaza-spiro[4.5]decan-4-on derivate als liganden des orl-1 rezeptors zur behandlung von angst und depression

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3826835A (en) * 1971-01-08 1974-07-30 Ciba Geigy Corp 8-benzofurylmethyl-1,3,8-triazaspiro(4,5)decanes as neuroleptics
US4749702A (en) * 1985-04-15 1988-06-07 Janssen Pharmaceutica N. V. Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines
US4826848A (en) * 1985-04-15 1989-05-02 Janssen Pharmaceutica N.V. Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines
US4689330A (en) * 1985-04-15 1987-08-25 Janssen Pharmaceutica N.V. Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines
US4957928A (en) * 1986-06-26 1990-09-18 Ciba-Geigy Corporation Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE3831888A1 (de) * 1988-09-20 1990-03-29 Troponwerke Gmbh & Co Kg Arzneimittel zur behandlung von apoplexia cerebri
DE4039631A1 (de) * 1990-12-12 1992-06-17 Troponwerke Gmbh & Co Kg Neuroprotektive kombination

Also Published As

Publication number Publication date
EP0539803A1 (de) 1993-05-05
JPH05222040A (ja) 1993-08-31
DE59209607D1 (de) 1999-02-18
FI924848A (fi) 1993-04-29
JP3257708B2 (ja) 2002-02-18
IL103546A0 (en) 1993-03-15
US6060482A (en) 2000-05-09
NO923974D0 (no) 1992-10-13
ES2125879T3 (es) 1999-03-16
DK0539803T3 (da) 1999-08-30
EP0539803B1 (de) 1999-01-07
AU2626592A (en) 1993-04-29
TW208010B (de) 1993-06-21
ATE175414T1 (de) 1999-01-15
CA2081256A1 (en) 1993-04-29
GR3029450T3 (en) 1999-05-28
NO923974L (no) 1993-04-29
CZ322492A3 (en) 1993-07-14
DE4135473A1 (de) 1993-04-29
MX9205869A (es) 1993-04-01
HUT64068A (en) 1993-11-29
AU650792B2 (en) 1994-06-30
HU9203382D0 (en) 1993-01-28
FI924848A0 (fi) 1992-10-26
ZA928290B (en) 1993-05-04

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