KR930005621A - 고혈압 치료용 제약 조성물 - Google Patents

고혈압 치료용 제약 조성물 Download PDF

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Publication number
KR930005621A
KR930005621A KR1019920017395A KR920017395A KR930005621A KR 930005621 A KR930005621 A KR 930005621A KR 1019920017395 A KR1019920017395 A KR 1019920017395A KR 920017395 A KR920017395 A KR 920017395A KR 930005621 A KR930005621 A KR 930005621A
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KR
South Korea
Prior art keywords
pharmaceutical composition
compound
configuration
carbon atom
treating hypertension
Prior art date
Application number
KR1019920017395A
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English (en)
Other versions
KR950013756B1 (ko
Inventor
로버트 라슨 에릭
Original Assignee
알렌 제이. 스피겔
화이자 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 알렌 제이. 스피겔, 화이자 인크. filed Critical 알렌 제이. 스피겔
Publication of KR930005621A publication Critical patent/KR930005621A/ko
Application granted granted Critical
Publication of KR950013756B1 publication Critical patent/KR950013756B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Removal Of Specific Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

본 발명은 특정 티아졸리딘-2,4-디온을 함유하는 고혈압 치료용 제약 조성물에 관한 것이다.

Description

고혈압 치료용 제약 조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 혈압 저하 유효량의 하기 일반식(Ⅰ)의 화합물, 제약상 허용되는 그의 양이온 염 또는 제약상 허용되는 그의 산 부가염 및 제약상 허용되는 담체로 이루어진 고혈압 치료용 제약 조성물.
    상기식에서, X는 C=0 또는 CH0H이다.
  2. 제1항에 있어서, X가 C=O인 제약 조성물.
  3. 제1항에 있어서, X가 CHOH이고 X의 탄소 원자가(R)배열을 가지며, 화합물이 X의 탄소원자가(S)배열을 갖는 대응하는 에난티오머로부터 실질적으로 유리된 화합물인 제약 조성물.
  4. 제1항에 있어서, X가 CHOH이고 X의 탄소 원자가(R)배열을 가지며, 화합물이 X의 탄소원자(R)배열을 갖는 대응하는 에난티오머로부터 실질적으로 유리된 화합물인 제약 조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019920017395A 1991-09-25 1992-09-24 고혈압 치료용 제약 조성물 KR950013756B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/765,643 US5175179A (en) 1991-09-25 1991-09-25 Method for treating hypertension
US765,643 1991-09-25

Publications (2)

Publication Number Publication Date
KR930005621A true KR930005621A (ko) 1993-04-20
KR950013756B1 KR950013756B1 (ko) 1995-11-15

Family

ID=25074097

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920017395A KR950013756B1 (ko) 1991-09-25 1992-09-24 고혈압 치료용 제약 조성물

Country Status (17)

Country Link
US (1) US5175179A (ko)
EP (1) EP0534655B1 (ko)
JP (1) JPH05194220A (ko)
KR (1) KR950013756B1 (ko)
AT (1) ATE124259T1 (ko)
AU (1) AU644545B2 (ko)
CA (1) CA2078901A1 (ko)
DE (1) DE69203194T2 (ko)
DK (1) DK0534655T3 (ko)
ES (1) ES2073871T3 (ko)
HU (1) HUT65276A (ko)
IL (1) IL103202A0 (ko)
MX (1) MX9205408A (ko)
MY (1) MY129918A (ko)
NZ (1) NZ244474A (ko)
TW (1) TW209167B (ko)
ZA (1) ZA927307B (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6290991B1 (en) * 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
CN101010323B (zh) * 2004-08-25 2010-06-16 埃科特莱茵药品有限公司 作为肾素抑制剂的双环壬烯衍生物
NZ564689A (en) * 2005-05-27 2011-02-25 Actelion Pharmaceuticals Ltd Novel piperidine carboxylic acid amide derivatives
KR20090008211A (ko) * 2006-03-08 2009-01-21 액테리온 파마슈티칼 리미티드 신규 아민

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989008651A1 (en) * 1988-03-08 1989-09-21 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
GB8919417D0 (en) * 1989-08-25 1989-10-11 Beecham Group Plc Novel compounds
US5053420A (en) * 1989-10-13 1991-10-01 Pershadsingh Harrihar A Thiazolidine derivatives for the treatment of hypertension
US5036079A (en) * 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
JP2826379B2 (ja) * 1990-01-22 1998-11-18 三共株式会社 チアゾリジン誘導体を有効成分とする肥満性高血圧症治療剤
WO1991012003A1 (en) * 1990-02-09 1991-08-22 The Upjohn Company Use of insulin sensitizing agents to treat hypertension

Also Published As

Publication number Publication date
AU644545B2 (en) 1993-12-09
CA2078901A1 (en) 1993-03-26
DK0534655T3 (da) 1995-08-28
KR950013756B1 (ko) 1995-11-15
EP0534655B1 (en) 1995-06-28
DE69203194T2 (de) 1995-11-02
MY129918A (en) 2007-05-31
US5175179A (en) 1992-12-29
DE69203194D1 (de) 1995-08-03
MX9205408A (es) 1993-03-01
HU9203052D0 (en) 1992-12-28
JPH05194220A (ja) 1993-08-03
EP0534655A1 (en) 1993-03-31
ES2073871T3 (es) 1995-08-16
ATE124259T1 (de) 1995-07-15
HUT65276A (en) 1994-05-02
AU2532692A (en) 1993-04-22
ZA927307B (en) 1994-03-24
TW209167B (ko) 1993-07-11
IL103202A0 (en) 1993-02-21
NZ244474A (en) 1994-01-26

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