KR930000113B1 - 아조니아스피로노르트로판올 에스테르의 제조방법 - Google Patents

아조니아스피로노르트로판올 에스테르의 제조방법 Download PDF

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Publication number
KR930000113B1
KR930000113B1 KR1019860011482A KR860011482A KR930000113B1 KR 930000113 B1 KR930000113 B1 KR 930000113B1 KR 1019860011482 A KR1019860011482 A KR 1019860011482A KR 860011482 A KR860011482 A KR 860011482A KR 930000113 B1 KR930000113 B1 KR 930000113B1
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KR
South Korea
Prior art keywords
formula
group
chloride
reaction
spiro
Prior art date
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Expired - Fee Related
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KR1019860011482A
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English (en)
Korean (ko)
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KR870005998A (ko
Inventor
볼프 그리민거 독토르
클라우스 괴르러 독토르
카알 페터 오덴탈 독토르
Original Assignee
마다우스 아크티엔 게젤샤프트
롤프 마다우스
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19853546218 external-priority patent/DE3546218A1/de
Priority claimed from DE19853546165 external-priority patent/DE3546165A1/de
Application filed by 마다우스 아크티엔 게젤샤프트, 롤프 마다우스 filed Critical 마다우스 아크티엔 게젤샤프트
Publication of KR870005998A publication Critical patent/KR870005998A/ko
Application granted granted Critical
Publication of KR930000113B1 publication Critical patent/KR930000113B1/ko
Anticipated expiration legal-status Critical
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/20—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20—Spiro-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1019860011482A 1985-12-27 1986-12-27 아조니아스피로노르트로판올 에스테르의 제조방법 Expired - Fee Related KR930000113B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DEP3546165.9 1985-12-27
DE19853546218 DE3546218A1 (de) 1985-12-27 1985-12-27 Azoniaspironortropanolester, verfahren zu deren herstellung und pharmazeutisches mittel
DEP3546218.3 1985-12-27
DE19853546165 DE3546165A1 (de) 1985-12-27 1985-12-27 Verwendung von azoniaspironortropanolestern als asthmatherapeutikum und als broncholytikum

Publications (2)

Publication Number Publication Date
KR870005998A KR870005998A (ko) 1987-07-08
KR930000113B1 true KR930000113B1 (ko) 1993-01-09

Family

ID=25839393

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019860011482A Expired - Fee Related KR930000113B1 (ko) 1985-12-27 1986-12-27 아조니아스피로노르트로판올 에스테르의 제조방법

Country Status (18)

Country Link
KR (1) KR930000113B1 (enExample)
AT (1) AT397962B (enExample)
AU (1) AU584266B2 (enExample)
BE (1) BE906054A (enExample)
CA (1) CA1304369C (enExample)
CH (1) CH677793A5 (enExample)
ES (1) ES2004177A6 (enExample)
FI (1) FI865295A7 (enExample)
FR (1) FR2598417B1 (enExample)
GB (1) GB2184726B (enExample)
HU (1) HU201930B (enExample)
IT (1) IT1198263B (enExample)
NL (1) NL193184C (enExample)
PL (1) PL150843B1 (enExample)
PT (1) PT84022B (enExample)
SE (1) SE8605531L (enExample)
SU (1) SU1711674A3 (enExample)
YU (1) YU46038B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2899418B2 (ja) * 1994-04-19 1999-06-02 ノイロサーチ アクティーゼルスカブ トロパン誘導体、それらの製造及び用途
AU2004289222B2 (en) * 2003-11-04 2010-01-21 Supernus Pharmaceuticals Inc. Compositions of quaternary ammonium containing bioavailability enhancers
MXPA06003769A (es) * 2003-11-04 2006-07-03 Shire Lab Inc Liberacion sostenida de moleculas farmacologicamente activas cargadas positivamente a partir de una matriz que contiene polimeros con atomos de oxigeno polarizados.
CN101684117B (zh) * 2008-09-27 2013-06-12 宁波市医药技术研究有限公司 去甲托品醇的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1194422B (de) * 1963-03-05 1965-06-10 Robert Pfleger Chem Fab Dr Verfahren zur Herstellung von Azoniaspironortropanderivaten
US3480626A (en) * 1967-05-18 1969-11-25 Chem Fab Dr R Pfleger Certain azoniaspironortropine derivatives
DE1670258C3 (de) * 1967-08-04 1976-01-02 C.H. Boehringer Sohn, 6507 Ingelheim Verfahren zur Herstellung von N or scopolamin durch Entalkylierung tertiärer, cyclischer Amine
IT1140998B (it) * 1980-06-18 1986-10-10 Valeas Ind Chimica E Farmaceut Sali di endo-8-metil-8-sin-alchil-8-azoniabiciclo aperta par. quadrata 3.2.1. chiusa par. quadrata-ottan-3-alchilcarbossilati, processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo

Also Published As

Publication number Publication date
HUT43060A (en) 1987-09-28
PL263216A1 (en) 1988-04-14
KR870005998A (ko) 1987-07-08
PT84022B (pt) 1989-07-31
SU1711674A3 (ru) 1992-02-07
SE8605531L (sv) 1987-06-28
HU201930B (en) 1991-01-28
AU584266B2 (en) 1989-05-18
CA1304369C (en) 1992-06-30
AU6698586A (en) 1987-07-02
SE8605531D0 (sv) 1986-12-22
FR2598417B1 (fr) 1993-10-29
FI865295L (fi) 1987-06-28
GB2184726B (en) 1990-10-03
FI865295A0 (fi) 1986-12-23
PT84022A (en) 1987-01-01
ES2004177A6 (es) 1988-12-16
CH677793A5 (enExample) 1991-06-28
IT1198263B (it) 1988-12-21
YU224986A (en) 1988-04-30
NL8603303A (nl) 1987-07-16
NL193184B (nl) 1998-10-01
IT8622877A0 (it) 1986-12-24
IT8622877A1 (it) 1988-06-24
PL150843B1 (en) 1990-07-31
NL193184C (nl) 1999-02-02
ATA339286A (de) 1993-12-15
FI865295A7 (fi) 1987-06-28
FR2598417A1 (fr) 1987-11-13
GB2184726A (en) 1987-07-01
AT397962B (de) 1994-08-25
BE906054A (fr) 1987-06-29
YU46038B (sh) 1992-12-21
GB8630809D0 (en) 1987-02-04

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