KR920016086A - 흡입용의 반응억제성 천식치료 활성을 갖는 비스테로이드성 소염제 - Google Patents

흡입용의 반응억제성 천식치료 활성을 갖는 비스테로이드성 소염제 Download PDF

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KR920016086A
KR920016086A KR1019920001737A KR920001737A KR920016086A KR 920016086 A KR920016086 A KR 920016086A KR 1019920001737 A KR1019920001737 A KR 1019920001737A KR 920001737 A KR920001737 A KR 920001737A KR 920016086 A KR920016086 A KR 920016086A
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South Korea
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nonsteroidal anti
inhalation
inflammatory agent
inflammatory drugs
inhibitory
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KR1019920001737A
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English (en)
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비안코 세바스티아노
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엥겔하르트, 라피체
훼스트 아크티엔게젤샤프트
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Publication of KR920016086A publication Critical patent/KR920016086A/ko

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/02Halogenated hydrocarbons
    • A61K31/025Halogenated hydrocarbons carbocyclic
    • A61K31/03Halogenated hydrocarbons carbocyclic aromatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • A61K31/612Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

내용 없음

Description

[발명의 명칭]
흡입용의 반응억제성 천식치료 활성을 갖는 비스테로이드성 소염제
[도면의 간단한 설명]
제1도는 L-ASA(100mg/m1)를 흡입 치료하고 30초후 및 24시간후에 측정한 UNW에 대한 기관지 반응성에 대한 L-ASA흡입 치료 효과를 도시한 것이다. 데이타는 UNW PD20의 M±SE로서 표시된다, 제2도는 UMW에 대한 기관지 반응성에 대한 인도메타신(5mg/m1)흡입 치료의 효과를 도시한 것이다.
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (10)

  1. 천식 치료를 위해 흡입되는 약제 제조용으로서의 비스테로이드성 소염제의 용도.
  2. 제1항에 있어서, 비스테로이드성 소염제가 아세틸 살리실산인 용도.
  3. 제1항에 있어서, 비스테로이드성 소염제가 인도메타신의 용도.
  4. 제1항에 있어서, 비스테로이드성 소염제가 케토프로펜인 용도.
  5. 제1항에 있어서, 비스테로이드성 소염제가 테녹시캄인 용도.
  6. 천식 억제시 흡입법으로 사용되는 비스테로이드성 소염제.
  7. 제6항에 있어서, 아세틸살리실산인 비스테로이드성 소염제.
  8. 제6항에 있어서, 인도메타신인 비스테로이드성 소염제.
  9. 제6항에 있어서, 케토프로펜인 비스테로이드성 소염제.
  10. 제6항에 있어서, 테녹시캄인 비스테로이드성 소염제.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019920001737A 1991-02-09 1992-02-07 흡입용의 반응억제성 천식치료 활성을 갖는 비스테로이드성 소염제 KR920016086A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP91101818.2 1991-02-09
EP91101818 1991-02-09

Publications (1)

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KR920016086A true KR920016086A (ko) 1992-09-24

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KR1019920001737A KR920016086A (ko) 1991-02-09 1992-02-07 흡입용의 반응억제성 천식치료 활성을 갖는 비스테로이드성 소염제

Country Status (16)

Country Link
US (1) US6051566A (ko)
JP (1) JPH0648958A (ko)
KR (1) KR920016086A (ko)
AT (1) ATE179605T1 (ko)
AU (1) AU662509B2 (ko)
BR (1) BR9200429A (ko)
CA (1) CA2060937A1 (ko)
CZ (1) CZ281970B6 (ko)
DE (1) DE69229070T2 (ko)
HU (1) HUT60917A (ko)
IE (1) IE920427A1 (ko)
IL (1) IL100896A (ko)
MX (1) MX9200571A (ko)
NO (1) NO179893C (ko)
NZ (1) NZ241542A (ko)
ZA (1) ZA92890B (ko)

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HUT60917A (en) 1992-11-30
AU662509B2 (en) 1995-09-07
NO920504D0 (no) 1992-02-07
CA2060937A1 (en) 1992-08-10
CS35292A3 (en) 1992-08-12
IE920427A1 (en) 1992-08-12
ZA92890B (en) 1992-12-30
HU9200389D0 (en) 1992-04-28
MX9200571A (es) 1992-12-01
NZ241542A (en) 1996-05-28
DE69229070T2 (de) 1999-11-18
IL100896A0 (en) 1992-11-15
DE69229070D1 (de) 1999-06-10
NO920504L (no) 1992-08-10
CZ281970B6 (cs) 1997-04-16
IL100896A (en) 1998-02-22
NO179893B (no) 1996-09-30
BR9200429A (pt) 1992-10-13
AU1077292A (en) 1992-08-13
ATE179605T1 (de) 1999-05-15
JPH0648958A (ja) 1994-02-22
US6051566A (en) 2000-04-18
NO179893C (no) 1997-01-08

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