KR920009387A - 약물 경피투여용 제제 - Google Patents

약물 경피투여용 제제 Download PDF

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Publication number
KR920009387A
KR920009387A KR1019910021715A KR910021715A KR920009387A KR 920009387 A KR920009387 A KR 920009387A KR 1019910021715 A KR1019910021715 A KR 1019910021715A KR 910021715 A KR910021715 A KR 910021715A KR 920009387 A KR920009387 A KR 920009387A
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KR
South Korea
Prior art keywords
pressure
meth
acrylic acid
sensitive
local anesthetic
Prior art date
Application number
KR1019910021715A
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English (en)
Other versions
KR0185715B1 (ko
Inventor
마사끼 수나미
고지 마르야마
미쯔히꼬 호리
쇼이찌 도꾸다
게니찌로 사이또
이꾸오 기시
Original Assignee
가마이 고로
닛또덴고 가부시끼가이샤
고니시 신베에, 히사나가 쇼이찌로
니혼레다리 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 가마이 고로, 닛또덴고 가부시끼가이샤, 고니시 신베에, 히사나가 쇼이찌로, 니혼레다리 가부시끼가이샤 filed Critical 가마이 고로
Publication of KR920009387A publication Critical patent/KR920009387A/ko
Application granted granted Critical
Publication of KR0185715B1 publication Critical patent/KR0185715B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

내용 없음

Description

약물 경피투여용 제제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (6)

  1. 유연성 있는 지지층 및 국소 마취제를 40내지 65중량%의 비로 함유하고, 그 속에 용해된 국소 마취제의 양(As)에 대한 용해되지 않은 국소 마취제의 양(Ac)의 비, Ac/As 가 0.1 내지 1.8인 감압성(prssure-sensitive) 점착제층을 포함함을 특징으로 하는 약물 경피투여용 제제.
  2. 제1항에 있어서, 국소 마취제를 아미드 마취제 및 에스테르 마취제로 이루어진 군으로 부터 하나 이상 선택함을 특징으로 하는 약물 경피투여용 제제.
  3. 제1항에 있어서, 국소 마취제를 코카인, 프로카인, 클로로프로카인, 테트라카인, 리도카인, 메피바카인, 프릴로카인, 부피바카인, 디부카인 및 약제학적으로 허용되는 이의 염으로 이루어진 군으로 부터 하나 이상 선택함을 특징으로 하는 약물 경피투여용 제제.
  4. 제1항에 있어서, 감압성 접착제층이 감압성 아크릴 점착제의 층임을 특징으로 하는 경피투여용 제제.
  5. 제4항에 있어서, 감압성 아크릴 점착제가 (메트) 아크릴산 알킬 에스테르 및 (메트) 아크릴산의 공중합체임을 특징으로 하는 약물 경피투여용 제제.
  6. 제4항에 있어서, 감압성 아크릴 점착제가 (메트) 아크릴산 알킬 에스테르 65 내지 99중량% 및 (메트) 아크릴산 1 내지 35중량%의 중합 반응에 의해 수득됨을 특징으로 하는 약물 경피투여용 제제.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019910021715A 1990-11-30 1991-11-29 약물 경피투여용 제제 KR0185715B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2338885A JP2849950B2 (ja) 1990-11-30 1990-11-30 経皮吸収製剤
JP90-338885 1990-11-30

Publications (2)

Publication Number Publication Date
KR920009387A true KR920009387A (ko) 1992-06-25
KR0185715B1 KR0185715B1 (ko) 1999-05-01

Family

ID=18322294

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910021715A KR0185715B1 (ko) 1990-11-30 1991-11-29 약물 경피투여용 제제

Country Status (10)

Country Link
US (1) US5368860A (ko)
EP (1) EP0488137B1 (ko)
JP (1) JP2849950B2 (ko)
KR (1) KR0185715B1 (ko)
AT (1) ATE120642T1 (ko)
CA (1) CA2056653C (ko)
DE (1) DE69108683T2 (ko)
DK (1) DK0488137T3 (ko)
ES (1) ES2070401T3 (ko)
TW (1) TW198692B (ko)

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WO1993020138A2 (en) * 1992-03-30 1993-10-14 Alza Corporation Polymer system containing a partially soluble compound
DE69517816T2 (de) 1994-09-14 2000-12-28 Minnesota Mining & Mfg Matrix für transdermale wirkstofffreisetzung
US5573778A (en) * 1995-03-17 1996-11-12 Adhesives Research, Inc. Drug flux enhancer-tolerant pressure sensitive adhesive composition
DE19524691A1 (de) * 1995-07-06 1997-01-09 Liedtke Pharmed Gmbh Methode und Zusammensetzung einer topischen Therapie von Innenohr und Labyrinth-Symptomen
US5667799A (en) * 1995-10-30 1997-09-16 Caldwell; Larry J. Method for treating headache pain with topical local anesthetic compositions
DE19546159A1 (de) * 1995-12-11 1997-06-12 Liedtke Pharmed Gmbh Methode und Zusammensetzung einer topisch wirksamen Therapie postoperativer und posttraumatischer Wundschmerzen
US6365178B1 (en) * 1996-09-06 2002-04-02 Watson Pharmaceuticals, Inc. Method of making pressure sensitive adhesive matrix patches for transdermal drug delivery using hydrophilic salts of drugs and hydrophobic pressure sensitive adhesive dispersions
US5985317A (en) * 1996-09-06 1999-11-16 Theratech, Inc. Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
US6103771A (en) * 1998-03-20 2000-08-15 Caldwell Galer Incorporated Method of treating neuroma pain
CA2343100A1 (en) * 1998-09-08 2000-05-04 Srinivasan Venkateshwaran Method of making pressure sensitive adhesive matrix patches containing hydrophilic salts of drugs
WO2001064149A1 (en) * 2000-02-29 2001-09-07 Jie Zhang Improved transdermal drug patch
WO2005107834A1 (en) 2004-04-30 2005-11-17 Clawson Burrell E Apparatus and methods for isolating human body areas for localized cooling
US7666914B2 (en) * 2004-06-03 2010-02-23 Richlin David M Topical preparation and method for transdermal delivery and localization of therapeutic agents
US20060079558A1 (en) * 2004-09-27 2006-04-13 Bridge Pharma. Inc. R-isomer of 2-{2[N-(2-indanyl)-N-phenylamino]ethyl}piperidine and other dermal anesthetics
US7718674B2 (en) * 2004-09-27 2010-05-18 Bridge Pharma, Inc. Methods of relieving neuropathic pain with the S-isomer of 2-{2[N-(2-indanyl)-N-phenylamino]ethyl}piperidine
JP2006248996A (ja) * 2005-03-10 2006-09-21 Nitto Denko Corp 経皮吸収型貼付剤
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CA2738524C (en) 2008-10-02 2013-11-26 Mylan Inc. Method for making a multilayer adhesive laminate
KR101080380B1 (ko) 2009-08-14 2011-11-04 한국수력원자력 주식회사 접착력이 향상된 수화겔 접착용 필름 및 이의 제조방법
KR101955175B1 (ko) * 2010-04-13 2019-03-06 나지브 바불 1-메틸-2'-6'-피페콜옥실리디드의 피부 약제학적 조성물 및 사용 방법
AU2016259348B9 (en) * 2010-04-13 2018-11-29 Relmada Therapeutics, Inc. Dermal pharmaceutical compositions of 1-Methyl-2',6' pipecoloxylidide and method of use
DE102011100619A1 (de) 2010-05-05 2012-01-05 Amw Gmbh Transdermales therapeutisches System (TTS) mit einem Gehalt an einem Opiod-Analgetikum
KR20170055487A (ko) * 2014-10-02 2017-05-19 닛토덴코 가부시키가이샤 경피 투여용 백신 의약 조성물
CN109316469B (zh) * 2018-10-09 2022-02-22 北京德默高科医药技术有限公司 一种稳定的高载药利多卡因透皮贴剂及其制备方法

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JPS58148815A (ja) * 1982-02-26 1983-09-05 Nitto Electric Ind Co Ltd 複合医薬製剤の製法
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Also Published As

Publication number Publication date
US5368860A (en) 1994-11-29
TW198692B (ko) 1993-01-21
JP2849950B2 (ja) 1999-01-27
EP0488137B1 (en) 1995-04-05
ES2070401T3 (es) 1995-06-01
DE69108683D1 (de) 1995-05-11
JPH04208229A (ja) 1992-07-29
CA2056653A1 (en) 1992-05-31
ATE120642T1 (de) 1995-04-15
KR0185715B1 (ko) 1999-05-01
DK0488137T3 (da) 1995-08-28
DE69108683T2 (de) 1995-10-05
EP0488137A3 (en) 1993-02-03
EP0488137A2 (en) 1992-06-03
CA2056653C (en) 2000-08-08

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