DE69108683T2 - Zubereitung zur transdermalen Verabreichung von Arzneimitteln. - Google Patents

Zubereitung zur transdermalen Verabreichung von Arzneimitteln.

Info

Publication number
DE69108683T2
DE69108683T2 DE69108683T DE69108683T DE69108683T2 DE 69108683 T2 DE69108683 T2 DE 69108683T2 DE 69108683 T DE69108683 T DE 69108683T DE 69108683 T DE69108683 T DE 69108683T DE 69108683 T2 DE69108683 T2 DE 69108683T2
Authority
DE
Germany
Prior art keywords
preparation
pressure
sensitive adhesive
adhesive layer
local anesthetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69108683T
Other languages
English (en)
Other versions
DE69108683D1 (de
Inventor
Sunami Masaki
Maruyama Koji
Hori Mitsuhiko
Tokuda Shoichi
Saito Kenichiro
Kishi Ikuo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nitto Denko Corp
Original Assignee
Lederle Japan Ltd
Nitto Denko Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lederle Japan Ltd, Nitto Denko Corp filed Critical Lederle Japan Ltd
Application granted granted Critical
Publication of DE69108683D1 publication Critical patent/DE69108683D1/de
Publication of DE69108683T2 publication Critical patent/DE69108683T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
DE69108683T 1990-11-30 1991-11-26 Zubereitung zur transdermalen Verabreichung von Arzneimitteln. Expired - Lifetime DE69108683T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2338885A JP2849950B2 (ja) 1990-11-30 1990-11-30 経皮吸収製剤

Publications (2)

Publication Number Publication Date
DE69108683D1 DE69108683D1 (de) 1995-05-11
DE69108683T2 true DE69108683T2 (de) 1995-10-05

Family

ID=18322294

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69108683T Expired - Lifetime DE69108683T2 (de) 1990-11-30 1991-11-26 Zubereitung zur transdermalen Verabreichung von Arzneimitteln.

Country Status (10)

Country Link
US (1) US5368860A (de)
EP (1) EP0488137B1 (de)
JP (1) JP2849950B2 (de)
KR (1) KR0185715B1 (de)
AT (1) ATE120642T1 (de)
CA (1) CA2056653C (de)
DE (1) DE69108683T2 (de)
DK (1) DK0488137T3 (de)
ES (1) ES2070401T3 (de)
TW (1) TW198692B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011100619A1 (de) 2010-05-05 2012-01-05 Amw Gmbh Transdermales therapeutisches System (TTS) mit einem Gehalt an einem Opiod-Analgetikum

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993020138A2 (en) * 1992-03-30 1993-10-14 Alza Corporation Polymer system containing a partially soluble compound
JP4102901B2 (ja) 1994-09-14 2008-06-18 スリーエム カンパニー 経皮薬剤導入用マトリックス
US5573778A (en) * 1995-03-17 1996-11-12 Adhesives Research, Inc. Drug flux enhancer-tolerant pressure sensitive adhesive composition
DE19524691A1 (de) * 1995-07-06 1997-01-09 Liedtke Pharmed Gmbh Methode und Zusammensetzung einer topischen Therapie von Innenohr und Labyrinth-Symptomen
US5667799A (en) * 1995-10-30 1997-09-16 Caldwell; Larry J. Method for treating headache pain with topical local anesthetic compositions
DE19546159A1 (de) * 1995-12-11 1997-06-12 Liedtke Pharmed Gmbh Methode und Zusammensetzung einer topisch wirksamen Therapie postoperativer und posttraumatischer Wundschmerzen
US5985317A (en) * 1996-09-06 1999-11-16 Theratech, Inc. Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
US6365178B1 (en) * 1996-09-06 2002-04-02 Watson Pharmaceuticals, Inc. Method of making pressure sensitive adhesive matrix patches for transdermal drug delivery using hydrophilic salts of drugs and hydrophobic pressure sensitive adhesive dispersions
US6103771A (en) * 1998-03-20 2000-08-15 Caldwell Galer Incorporated Method of treating neuroma pain
JP2003520191A (ja) * 1998-09-08 2003-07-02 ワトソン ファーマシューティカルズ, インコーポレイテッド 薬物の親水性塩類を含有する感圧接着剤マトリックスパッチの製造方法
EP1280485A4 (de) * 2000-02-29 2006-11-29 Zars Inc Verbessertes transdermales medizinpflaster
CA2564822A1 (en) 2004-04-30 2005-11-17 Burrell E. Clawson Apparatus and methods for isolating human body areas for localized cooling
US7666914B2 (en) * 2004-06-03 2010-02-23 Richlin David M Topical preparation and method for transdermal delivery and localization of therapeutic agents
WO2006036936A2 (en) * 2004-09-27 2006-04-06 Bridge Pharma, Inc. The s-isomer of 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine and other dermal anesthetic agents
WO2006037047A2 (en) * 2004-09-27 2006-04-06 Bridge Pharma, Inc. The r-isomer of 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine and other dermal anesthetic agents
JP2006248996A (ja) * 2005-03-10 2006-09-21 Nitto Denko Corp 経皮吸収型貼付剤
WO2008011161A2 (en) * 2006-07-21 2008-01-24 Bridge Pharma, Inc. Dermal anesthetic compounds
ES2388355T3 (es) 2006-11-03 2012-10-11 Durect Corporation Sistemas de suministro transdémico que comprenden bupivacaína
RU2497679C2 (ru) 2008-10-02 2013-11-10 Милан Инк. Способ получения многослойного клеящегося ламинированного материала
KR101080380B1 (ko) 2009-08-14 2011-11-04 한국수력원자력 주식회사 접착력이 향상된 수화겔 접착용 필름 및 이의 제조방법
KR101955175B1 (ko) * 2010-04-13 2019-03-06 나지브 바불 1-메틸-2'-6'-피페콜옥실리디드의 피부 약제학적 조성물 및 사용 방법
AU2016259348B9 (en) * 2010-04-13 2018-11-29 Relmada Therapeutics, Inc. Dermal pharmaceutical compositions of 1-Methyl-2',6' pipecoloxylidide and method of use
CA2960940A1 (en) * 2014-10-02 2016-04-07 Nitto Denko Corporation Vaccine pharmaceutical composition for transdermal administration
CN109316469B (zh) * 2018-10-09 2022-02-22 北京德默高科医药技术有限公司 一种稳定的高载药利多卡因透皮贴剂及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58148815A (ja) * 1982-02-26 1983-09-05 Nitto Electric Ind Co Ltd 複合医薬製剤の製法
GB2156215B (en) * 1984-03-05 1988-03-02 Nitto Electric Ind Co Percutaneous absorption type adhesive pharmaceutical preparation
US4655768A (en) * 1984-07-06 1987-04-07 Avery International Corporation Bandage for sustained delivery of drugs
US4764381A (en) * 1985-12-06 1988-08-16 Key Pharmaceuticals, Inc. Percutaneous penetration enhancer of oleic acid and 2-ethyl-1, 3-hexanediol
EP0331392A3 (de) * 1988-03-01 1990-02-14 Alza Corporation Anästhesie und Antisepsis von Haut
WO1989011872A1 (en) * 1988-06-09 1989-12-14 Alza Corporation Permeation enhancer comprising ethanol and glycerol monooleate
US5120325A (en) * 1991-06-12 1992-06-09 Fleshtones Products Co., Inc. Color-matched sterile adhesive bandages containing melanin-like pigment composition

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011100619A1 (de) 2010-05-05 2012-01-05 Amw Gmbh Transdermales therapeutisches System (TTS) mit einem Gehalt an einem Opiod-Analgetikum

Also Published As

Publication number Publication date
ES2070401T3 (es) 1995-06-01
CA2056653A1 (en) 1992-05-31
TW198692B (de) 1993-01-21
EP0488137A2 (de) 1992-06-03
EP0488137A3 (en) 1993-02-03
DE69108683D1 (de) 1995-05-11
JP2849950B2 (ja) 1999-01-27
US5368860A (en) 1994-11-29
EP0488137B1 (de) 1995-04-05
DK0488137T3 (da) 1995-08-28
KR920009387A (ko) 1992-06-25
JPH04208229A (ja) 1992-07-29
ATE120642T1 (de) 1995-04-15
KR0185715B1 (ko) 1999-05-01
CA2056653C (en) 2000-08-08

Similar Documents

Publication Publication Date Title
DE69108683T2 (de) Zubereitung zur transdermalen Verabreichung von Arzneimitteln.
KR0184867B1 (ko) 2-아미노-6-n-프로필아미노-4,5,6,7-테트라하이드로벤조티아졸의 경피투여
US5538736A (en) Active substance-containing plaster for the controlled administration of active substances to the skin
DK549489A (da) Adhaesivt dermalt laegemiddelpraeparat
JPH10508856A (ja) スキンケア組成物及びその適用方法
PT92830A (pt) Dispositivo adesivo para aplicacao dermica
ATE204178T1 (de) Methode zur behandlung und vorbeugung von typ-1 diabetis durch orale verabreichung von insulin
MY107088A (en) Plaster used as therapeutic system for the administration of active substances to the skin, which exhibits a graduated active substance release,process for the production of the plaster and use thereof
ATE118362T1 (de) Fixierpflaster.
AU709288B2 (en) Transdermal therapeutic system (tts) for the administration of drugs for treatment of drug dependency or drug addiction
FI901290A0 (fi) Foerfarande foer framstaellning av ett transdermalt terapeutiskt system med stegvis frigoering av det aktiva aemnet och anvaendning av detta foer lokal eller systemisk administrering av det aktiva aemnet.
WO1994017792A3 (en) Compositions and methods for transdermal drug delivery
US6207183B1 (en) Surface-stabilized pharmaceutical preparation for application on the skin
KR910021238A (ko) 켈로이드 치료제
JP3064402B2 (ja) 硝酸イソソルビド含有貼付剤
JP2001505222A (ja) 生物体にペプチド系医薬を導入するための局所用製剤
DK0880366T3 (da) Farmaceutisk præparat med adhæsion til huden, især et transdermalt terapeutisk system til afgivelse af 17-beta-estradiol til den menneskelige organisme
WO1992002206A1 (en) Lyophilized native collagen sheets comprising cosmetic formulations for the treatment of couperose
JPS5735511A (en) Dermatic medicine for external application
DE59307089D1 (de) Transdermales therapeutisches system zur verabreichung von physostigmin an die haut und verfahren zu dessen herstellung
JPH01299217A (ja) 硬膏剤
JPS6296430A (ja) 経皮・経粘膜製剤
JPH11512404A (ja) シラトラン化合物の経皮吸収型製剤
JPH11100310A (ja) 痩身化粧料を含浸させた部分痩身用不織布
JPH0624986A (ja) エペリゾンまたはその塩を含む経皮吸収製剤用組成物および経皮吸収製剤

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NITTO DENKO CORP., IBARAKI, OSAKA, JP

Owner name: WYETH K.K., TOKIO/TOKYO, JP

8327 Change in the person/name/address of the patent owner

Owner name: NITTO DENKO CORP., IBARAKI, OSAKA, JP