KR890015732A - 소염성 겔 - Google Patents

소염성 겔 Download PDF

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Publication number
KR890015732A
KR890015732A KR1019890005214A KR890005214A KR890015732A KR 890015732 A KR890015732 A KR 890015732A KR 1019890005214 A KR1019890005214 A KR 1019890005214A KR 890005214 A KR890005214 A KR 890005214A KR 890015732 A KR890015732 A KR 890015732A
Authority
KR
South Korea
Prior art keywords
gel
range
inflammatory
ethanolamine
arginine
Prior art date
Application number
KR1019890005214A
Other languages
English (en)
Inventor
이언 페인 니콜러스
Original Assignee
알퐁스 아아르 노에
아메리칸 사이아나밋드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 알퐁스 아아르 노에, 아메리칸 사이아나밋드 캄파니 filed Critical 알퐁스 아아르 노에
Publication of KR890015732A publication Critical patent/KR890015732A/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음

Description

소염성 겔
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (6)

  1. 겔을 생성하기에 충분한 양의 카르복시비닐 중합체, 용매로서의 물, pH를 pH7.0-9.5의 범위내로 올리기에 충분한 양의 에탄올아민 및/또는 L-아르기닌, 하기 일반식의 구조적 부분을 가지는 비-스테로이달 소염성 약제를 포함하는 소염성 겔 :
    상기식에서, n은 0또는 1이고 R1및 R2는 각각 수소 또는 알킬이다.
  2. 제 1 항에 있어서, 소염성 약제가 4-비페닐아세트산인 겔.
  3. 제 1 항 또는 제 2 항에 있어서, L-아르기닌이 사용된 겔.
  4. 제 3 항에 있어서, pH가 8.5-9.2의 범위내인 겔.
  5. 제 1 항 또는 제 2 항에 있어서, 에탄올아민이 사용된 겔.
  6. 제 5 항에 있어서, pH가 7.1-7.8범위내인 겔.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890005214A 1988-04-21 1989-04-20 소염성 겔 KR890015732A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8809424A GB2217595B (en) 1988-04-21 1988-04-21 Antiinflammatory gel
GB8809424.8 1988-04-21

Publications (1)

Publication Number Publication Date
KR890015732A true KR890015732A (ko) 1989-11-25

Family

ID=10635577

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890005214A KR890015732A (ko) 1988-04-21 1989-04-20 소염성 겔

Country Status (11)

Country Link
EP (1) EP0338291A1 (ko)
JP (1) JPH026407A (ko)
KR (1) KR890015732A (ko)
AU (1) AU615736B2 (ko)
DK (1) DK193089A (ko)
FI (1) FI891886A (ko)
GB (1) GB2217595B (ko)
NO (1) NO891618L (ko)
NZ (1) NZ228750A (ko)
PT (1) PT90313A (ko)
ZA (1) ZA892922B (ko)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2839164B2 (ja) * 1989-12-25 1998-12-16 帝國製薬株式会社 消炎鎮痛貼付剤
US5093133A (en) * 1990-01-24 1992-03-03 Mcneil-Ppc, Inc. Method for percutaneous delivery of ibuprofen using hydroalcoholic gel
GB2260079B (en) * 1991-10-01 1995-08-09 American Cyanamid Co Pharmaceutical composition containing felbinac
US5364884A (en) * 1993-01-21 1994-11-15 Baylor College Of Medicine Arginine compounds as ocular hypotensive agents
GB2305603A (en) * 1995-09-26 1997-04-16 Allied Medical Group Topical cooling gels for reducing excess body fat
US5702720A (en) * 1995-12-22 1997-12-30 Minnesota Mining And Manufacturing Company Transdermal device for the delivery of flurbiprofen
GB9718568D0 (en) 1997-09-03 1997-11-05 Chauvin Pharmaceuticals Limite Compositions
US7629384B2 (en) 1997-09-17 2009-12-08 Strategic Science & Technologies, Llc Topical delivery of L-arginine to cause beneficial effects
US7914814B2 (en) 1997-09-17 2011-03-29 Strategic Science & Technologies, Llc Topical delivery of arginine of cause beneficial effects
FR2797766B1 (fr) * 1999-08-27 2003-04-04 Menarini France Nouvelles formes topiques a consistance pateuse sous forme d'un gel distribue en doses
JP2004123575A (ja) * 2002-09-30 2004-04-22 Rohto Pharmaceut Co Ltd 外用ゲル状組成物
US7332516B2 (en) 2003-01-14 2008-02-19 Merck + Co., Inc. Geminally di-substituted NSAID derivatives as Aβ42 lowering agents
CA2563670C (en) 2004-04-19 2014-09-16 Strategic Science & Technologies, Llc Transdermal delivery of beneficial substances effected by a hostile biophysical environment
US9226909B2 (en) 2004-04-19 2016-01-05 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
EP2417979A1 (en) * 2004-04-19 2012-02-15 Strategic Science & Technologies, LLC Beneficial effects of increasing local blood flow
US11684624B2 (en) 2009-06-24 2023-06-27 Strategic Science & Technologies, Llc Treatment of erectile dysfunction and other indications
US8604081B2 (en) 2009-06-24 2013-12-10 Strategic Science & Technologies, Llc Topical composition containing ibuprofen
US9072659B2 (en) 2009-06-24 2015-07-07 Strategic Science & Technologies, Llc Topical composition containing naproxen
EP2658551B1 (en) 2010-12-29 2020-07-01 Strategic Science & Technologies, LLC Treatment of erectile dysfunction and other indications
JP2014501283A (ja) 2010-12-29 2014-01-20 ストラテジック サイエンス アンド テクノロジーズ， エルエルシー アレルギーおよび他の適応症の処置のためのシステムおよび方法
CN102885803A (zh) * 2011-12-29 2013-01-23 广东中科药物研究有限公司 联苯乙酸氨丁三醇盐在制备治疗眼部炎症反应药物中的应用
CN104262138B (zh) * 2014-08-22 2016-05-11 湖北美林药业有限公司 一种联苯乙酸化合物及其药物组合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59222409A (ja) * 1983-06-01 1984-12-14 Nippon Redarii Kk 消炎鎮痛ゲル軟膏剤
JPS63174924A (ja) * 1987-01-14 1988-07-19 Toko Yakuhin Kogyo Kk 軟膏基剤および軟膏剤

Also Published As

Publication number Publication date
GB2217595B (en) 1991-11-20
DK193089D0 (da) 1989-04-20
FI891886A0 (fi) 1989-04-20
FI891886A (fi) 1989-10-22
AU3325189A (en) 1989-10-26
GB2217595A (en) 1989-11-01
DK193089A (da) 1989-10-22
NZ228750A (en) 1991-05-28
JPH026407A (ja) 1990-01-10
NO891618L (no) 1989-10-23
PT90313A (pt) 1989-11-10
NO891618D0 (no) 1989-04-20
ZA892922B (en) 1989-12-27
AU615736B2 (en) 1991-10-10
GB8809424D0 (en) 1988-05-25
EP0338291A1 (en) 1989-10-25

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