KR910021480A - 유기산의 생물학적 제조방법 - Google Patents

유기산의 생물학적 제조방법 Download PDF

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Publication number
KR910021480A
KR910021480A KR1019910003383A KR910003383A KR910021480A KR 910021480 A KR910021480 A KR 910021480A KR 1019910003383 A KR1019910003383 A KR 1019910003383A KR 910003383 A KR910003383 A KR 910003383A KR 910021480 A KR910021480 A KR 910021480A
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South Korea
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rhodococcus
group
aromatic
nitrile
compound
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KR1019910003383A
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KR0143981B1 (ko
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히데아키 야마다
도루 나가사와
테츠지 나카무라
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히데아키 야마다
이토 타이조
니토가가쿠고교 가부시키가이샤
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

내용 없음

Description

유기산의 생물학적 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (13)

  1. 미생물의 고유한 니틀릴라제효소의 작용에 의해 니트릴화합물을 그에 상응하는 유기산으로 전환시켜서 유기산을 제조하는데 있어서, 상기 효소는 락탐화합물의 존재하에 미생물 균주인 로도코커스를 배양시켜서 얻어진 효소를 사용하여서 되는 유기산의 생물학적 제조방법.
  2. 제1항에 있어서, 미생물 균주인 로도코커스는 로드코커스 로도크로스의 그룹에서 선택하여서 되는 방법.
  3. 제2항에 있어서, 로도코커스 로도크로스는 Rh. 로도크로스 J-1, FERM BP-1478 및 Rh. 로드크로스 ATCC 33278로 이루어진 그룹에서 선택하여서 되는 방법.
  4. 제3항에 잇어서, 로도코커스 로도크로스는 Rh. 로드크로스 J-1, FERM BP-1478인 방법.
  5. 제1항에 있어서, 상기 로도코커스는 로도코커스 sp. NCIB 11215 및 로도코커스 sp. NCIB 11216으로 이루어진 그룹에서 선택하여서 되는 방법.
  6. 제1항에 있어서, 상기 락탐화합물은 4 내지 6의 탄소원자를 갖는 고리분자간 아미드의 그룹에서 선택하여서 되는 방법.
  7. 제1항에 있어서, 락탐화합물의 양은 미생물 균주인 로도코커스가 배양되는 배지에 대하여 0.05 내지 2.0w/v%의 범위로 하여서 되는 방법.
  8. 제1항에 있어서, 상기 니트릴 화합물은 지방족, 방향족 모노니트릴 및 디니트릴로 이루어진 그룹에서 선택하여서 되는 방법.
  9. 제1항에 있어서, 상기 니트릴 화합물은 2 내지 6의 탄소원자를 갖는 지방족 모노니트릴 및 디니트릴로 이루어진 그룹에서 선택하여서 되는 방법.
  10. 제9항에 있어서, 상기 니트릴 화합물은 아크릴로니틀리로 하여서 되는 방법.
  11. 제1항에 있어서, 상기 니트릴 화합물은 방향족 핵속에 4 내지 10의 탄소원자를 갖는 방향족 모노니트릴 및 디니트릴로 이루어진 그룹에서 선택하여서 되는 방법.
  12. 제11항에 있어서, 상기 니트릴 화합물은 다음 구조식〔Ⅰ〕4 내지〔Ⅶ〕로 이루어진 그룹에서 방향족 니틀리로 하여서 되는 방법.
    상기식에서, R1과R2는 각각 H, CH3, OH, OCH3, OC2H5, CI, F, CN, NH2또는 NO2이다.
    상기식에서 X는 S 또는 0이다.
  13. 제12항에 있어서, 상기 방향족 니트릴은 상기 구조식〔Ⅰ〕의 시아노 피리딘으로 하여서 되는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019910003383A 1990-02-28 1991-02-28 유기산의 생물학적 제조방법 KR0143981B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2048134A JP3009421B2 (ja) 1990-02-28 1990-02-28 有機酸の生物学的製造法
JP48134/1990 1990-02-28

Publications (2)

Publication Number Publication Date
KR910021480A true KR910021480A (ko) 1991-12-20
KR0143981B1 KR0143981B1 (ko) 1998-07-01

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Country Link
US (1) US5135858A (ko)
EP (1) EP0444640B1 (ko)
JP (1) JP3009421B2 (ko)
KR (1) KR0143981B1 (ko)
CN (1) CN1034129C (ko)
DE (1) DE69125877T2 (ko)

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DD274631A5 (de) * 1987-09-18 1989-12-27 Kk Verfahren zur biologischen herstellung von amiden
US5266469A (en) * 1991-03-18 1993-11-30 Lonza Ltd. Microbiological process for the production of 6-hydroxynicotinic acid
US5264361A (en) * 1991-03-18 1993-11-23 Lonza Ltd. Microbiological process for the production of 6-hydroxypicolinic acid
US5264362A (en) * 1991-03-18 1993-11-23 Lonza Ltd. Microbiological process for the production of 6-hydroxynicotinic acid
US5270203A (en) * 1992-03-13 1993-12-14 Lonza Ltd. Biologically pure culture of Alcaligenes faecalis DSM 6335
JP2590434B2 (ja) * 1994-03-31 1997-03-12 工業技術院長 ３，４−ジヒドロキシフタル酸の製造方法
US5814497A (en) * 1994-09-22 1998-09-29 Rhone-Poulenc Nutrition Animale Enzymatic hydrolysis of racemic a-substituted 4-methylthiobutyronitriles using a nitrilase from alcaligenes faecalis, gordona terrae or rhodococcus sp
FR2731438B1 (fr) * 1995-03-07 1997-05-16 Rhone Poulenc Nutrition Animal Hydrolise enzymatique des 4-methylthiobutyronitriles
CA2177651C (en) * 1995-06-07 2008-01-22 Andreas Kiener Microbiological process for the preparation of heteroaromatic carboxylic acids using microorganisms of the genus alcaligenes
WO1997006248A1 (en) * 1995-08-09 1997-02-20 Allied Colloids Limited Processes for the production of amidase
DE19545303C1 (de) * 1995-12-05 1997-04-24 Metallgesellschaft Ag Verfahren zur Herstellung einer organischen Säure
JP3875722B2 (ja) * 1995-12-12 2007-01-31 チバ スペシャリティー ケミカルズ ウォーター トリートメンツ リミテッド アクリル酸アンモニウムの製造
GB9525372D0 (en) * 1995-12-12 1996-02-14 Allied Colloids Ltd Enzymes, their preparation and their use in the production of ammonium acrylate
ES2285728T3 (es) * 1996-02-29 2007-11-16 Nippon Soda Co., Ltd. Procedimiento para la preparacion de alfa hidroxiacidos empleando un microorganismo, y un nuevo microorganismo.
US5858736A (en) * 1996-05-17 1999-01-12 E. I. Du Pont De Nemours And Company Preparation of lactams from aliphatic α,ω-dinitriles
US6060265A (en) * 1996-12-18 2000-05-09 Cytec Technology Corporation Methods for the detoxification of nitrile and/or amide compounds
US5863750A (en) * 1996-12-18 1999-01-26 Cytec Tech Corp Methods for the detoxification of nitrile and/or amide compounds
US5866379A (en) * 1997-01-28 1999-02-02 Novus International Enzymatic conversion of α-hydroxynitriles to the corresponding .alpha.
WO1998058072A1 (en) * 1997-06-19 1998-12-23 Ciba Speciality Chemicals Water Treatments Limited Flocculation of biological material from organic acid-containing systems
US6153415A (en) * 1998-04-29 2000-11-28 Board Of Trustees Operating Michigan State University Method for producing amide compounds using a nitrile hydratase from a thermophilic bacillus
NL1011867C2 (nl) * 1999-04-22 2000-10-24 Dsm Nv Werkwijze voor de bereiding van een lineair, onverzadigd C3 - C8 carbonzuur.
DE10010149A1 (de) * 2000-03-03 2001-09-06 Basf Ag Nitrilase aus Rhodococcus rhodochrous NCIMB 11216
RU2177034C1 (ru) * 2001-04-03 2001-12-20 Закрытое акционерное общество "Биоамид" Штамм бактерий alcaligenes denitrificans-продуцент нитрилазы
US6670158B2 (en) 2002-02-05 2003-12-30 E. I. Du Pont De Nemours And Company Method for producing methacrylic acid acrylic acid with a combination of enzyme catalysts
EP1689861B1 (en) * 2003-12-02 2011-11-09 Ciba Specialty Chemicals Water Treatments Limited Strain of rhodococcus rhodochrous ncimb 41164 and its use as producer of nitrile hydratase
EP1789594A1 (en) * 2004-08-20 2007-05-30 Danmarks og Gronlands Geologiske Undersogelse Bam mineralizing activity
CN101268197A (zh) * 2005-09-22 2008-09-17 阿斯利康(瑞典)有限公司 用于将芳香卤代二腈转化为卤代氰基羧酸的新方法
CN103562379A (zh) * 2011-05-19 2014-02-05 国立大学法人德岛大学 细胞分化诱导剂以及分化诱导方法

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DD274631A5 (de) * 1987-09-18 1989-12-27 Kk Verfahren zur biologischen herstellung von amiden

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Publication number Publication date
DE69125877T2 (de) 1997-08-14
EP0444640A2 (en) 1991-09-04
US5135858A (en) 1992-08-04
JP3009421B2 (ja) 2000-02-14
DE69125877D1 (de) 1997-06-05
CN1055954A (zh) 1991-11-06
EP0444640A3 (en) 1992-07-08
CN1034129C (zh) 1997-02-26
EP0444640B1 (en) 1997-05-02
KR0143981B1 (ko) 1998-07-01
JPH03251192A (ja) 1991-11-08

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