KR910009247A - 유화 조성물 - Google Patents

유화 조성물 Download PDF

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Publication number
KR910009247A
KR910009247A KR1019900018642A KR900018642A KR910009247A KR 910009247 A KR910009247 A KR 910009247A KR 1019900018642 A KR1019900018642 A KR 1019900018642A KR 900018642 A KR900018642 A KR 900018642A KR 910009247 A KR910009247 A KR 910009247A
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KR
South Korea
Prior art keywords
polyoxyethylene
fatty acid
acid ester
composition
emulsion composition
Prior art date
Application number
KR1019900018642A
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English (en)
Inventor
히데오 나카지마
미유키 오카베
사토시 토모마사
Original Assignee
후쿠하라 요시하루
가부시키가이샤 시세이도
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 후쿠하라 요시하루, 가부시키가이샤 시세이도 filed Critical 후쿠하라 요시하루
Publication of KR910009247A publication Critical patent/KR910009247A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
    • Y10S516/01—Wetting, emulsifying, dispersing, or stabilizing agents
    • Y10S516/06—Protein or carboxylic compound containing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/788—Of specified organic or carbon-based composition
    • Y10S977/797—Lipid particle
    • Y10S977/798—Lipid particle having internalized material
    • Y10S977/799—Containing biological material
    • Y10S977/801—Drug
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Colloid Chemistry (AREA)

Abstract

내용 없음

Description

유화 조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 당 또는 당 알콜 농도와 입자크기와의 관계를 나타낸 그래프.

Claims (7)

  1. (A)지용성 약제 및 지질; (B)당, 당 알콜, 또는 이의 혼합물; (C)물: (D)분자량이 1000이상인 수용성, 바이온성계면활성제를 포함함을 특징으로 하는 유화조성물[여기서, (A)/(D)는 0.5 내지 5(중량비)이고, 조성물 중의 유화입자의 평균 입자 크리근 0.010 내지 0.07㎕이다.]
  2. 제1항에 있어서, 유화동안에 몰에 대한 당, 당 알콜 또는 이의 혼합물의 비율(중량비)이 2:8 내지 7:3인 유화 조성물.
  3. 제1항에 있어서, 지질이 식물성 오일, 글리세라이드, 스테롤, 콜레스테롤 에스테르 및 모노에스테르 중에서 선택되는 하나 이상의 성분인 유화 조성물.
  4. 제1항에 있어서, 인지질이 난황 및 식물성 종자로부터 유동되는 레시틴, 이의 수소화 생성물, 포스페티딜콜린, 포스페티딜에탄올아민, 포스페티딜리노시토, 포스페티딜세린, 스핀고마이엘린, 포스페티드산 및 피토글리콜리피드중에서 선택되는 하나이상의 성분인 유화 조성물.
  5. 제1항에 있어서, 수용성, 바이온성 계면활성제가 폴리옥시에티렌 슬비탄 지방산 에스테르, 폴리옥시에틸렌 슬비톨 지방산 에스테르, 폴리옥시에틸렌 글리세린 지방산 에스테르, 폴리옥시에틸렌 지방산 에스테를, 폴리옥 시에텔렌 알킬 에테르, 폴리옥시에틸렌 스태롤 에테르, 폴리옥시에틸렌-폴리옥시프로필렌 알킬 에테르, 폴리옥시에틸렌 캐스터 오일, 수소화된 캐스터 오일 유도체, 콜레스테롤 유도체 및 폴리글리세린 지방산 에스테르 중에서 선택되는 하나 이상의 성분인 유화 조성물.
  6. 제1항에 있어서, 바이온성 계면활성제에 대한 인지질의 중량비가 9.5/0.5 내지 1/9인 유화 조성물.
  7. 제1항에 있어서, 성분(A)/(B)/(C)/(D)의 중량비가 1 내지 30/5내지 50/20내지 92/0.5내지 20인 유화 조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900018642A 1989-11-20 1990-11-17 유화 조성물 KR910009247A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1302443A JP2785981B2 (ja) 1989-11-20 1989-11-20 乳化組成物
JP1-302443 1989-11-20

Publications (1)

Publication Number Publication Date
KR910009247A true KR910009247A (ko) 1991-06-28

Family

ID=17908998

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900018642A KR910009247A (ko) 1989-11-20 1990-11-17 유화 조성물

Country Status (5)

Country Link
US (1) US5098606A (ko)
EP (1) EP0429248A3 (ko)
JP (1) JP2785981B2 (ko)
KR (1) KR910009247A (ko)
CA (1) CA2030029A1 (ko)

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Also Published As

Publication number Publication date
US5098606A (en) 1992-03-24
EP0429248A3 (en) 1991-08-07
EP0429248A2 (en) 1991-05-29
CA2030029A1 (en) 1991-05-21
JPH03161430A (ja) 1991-07-11
JP2785981B2 (ja) 1998-08-13

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