KR910005886B1 - 연골조직의 치료약제 - Google Patents

연골조직의 치료약제 Download PDF

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Publication number
KR910005886B1
KR910005886B1 KR1019880007369A KR880007369A KR910005886B1 KR 910005886 B1 KR910005886 B1 KR 910005886B1 KR 1019880007369 A KR1019880007369 A KR 1019880007369A KR 880007369 A KR880007369 A KR 880007369A KR 910005886 B1 KR910005886 B1 KR 910005886B1
Authority
KR
South Korea
Prior art keywords
tissue
angiogenic factors
angiogenic
meniscus
vol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019880007369A
Other languages
English (en)
Korean (ko)
Other versions
KR890000101A (ko
Inventor
엘. 발리 버트
브이. 킹 토마스
Original Assignee
프레지던트 앤드 휄로우즈 오브 하버드 칼리지
죠이스 브린톤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/064,215 external-priority patent/US4952404A/en
Application filed by 프레지던트 앤드 휄로우즈 오브 하버드 칼리지, 죠이스 브린톤 filed Critical 프레지던트 앤드 휄로우즈 오브 하버드 칼리지
Publication of KR890000101A publication Critical patent/KR890000101A/ko
Application granted granted Critical
Publication of KR910005886B1 publication Critical patent/KR910005886B1/ko
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1891—Angiogenesic factors; Angiogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Zoology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
KR1019880007369A 1987-06-19 1988-06-18 연골조직의 치료약제 Expired KR910005886B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US064215 1987-06-19
US064,215 1987-06-19
US07/064,215 US4952404A (en) 1987-06-19 1987-06-19 Promotion of healing of meniscal tissue
US07/204,097 US4952403A (en) 1987-06-19 1988-06-08 Implants for the promotion of healing of meniscal tissue
US204097 1988-06-08

Publications (2)

Publication Number Publication Date
KR890000101A KR890000101A (ko) 1989-03-11
KR910005886B1 true KR910005886B1 (ko) 1991-08-06

Family

ID=26744280

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880007369A Expired KR910005886B1 (ko) 1987-06-19 1988-06-18 연골조직의 치료약제

Country Status (11)

Country Link
US (1) US4952403A (cg-RX-API-DMAC10.html)
EP (1) EP0295721B1 (cg-RX-API-DMAC10.html)
JP (1) JPS6486974A (cg-RX-API-DMAC10.html)
KR (1) KR910005886B1 (cg-RX-API-DMAC10.html)
AU (1) AU605599B2 (cg-RX-API-DMAC10.html)
CA (1) CA1326817C (cg-RX-API-DMAC10.html)
DE (1) DE3867328D1 (cg-RX-API-DMAC10.html)
DK (1) DK333788A (cg-RX-API-DMAC10.html)
ES (1) ES2027728T3 (cg-RX-API-DMAC10.html)
GR (1) GR3004229T3 (cg-RX-API-DMAC10.html)
PT (1) PT87753B (cg-RX-API-DMAC10.html)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990015586A2 (en) * 1989-06-05 1990-12-27 Massachusetts Institute Of Technology Bioerodible polymers for drug delivery in bone
US6054122A (en) * 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6197325B1 (en) * 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6117425A (en) * 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
US7196054B1 (en) 1990-11-27 2007-03-27 The American National Red Cross Methods for treating wound tissue and forming a supplemented fibrin matrix
US6559119B1 (en) 1990-11-27 2003-05-06 Loyola University Of Chicago Method of preparing a tissue sealant-treated biomedical material
EP0564502B1 (en) * 1990-11-27 2002-01-30 The American National Red Cross Tissue sealant and growth factor containing compositions that promote accelerated wound healing
US5206023A (en) * 1991-01-31 1993-04-27 Robert F. Shaw Method and compositions for the treatment and repair of defects or lesions in cartilage
US5201728A (en) * 1991-05-03 1993-04-13 Giampapa Vincent C Subcutaneous implantable multiple-agent delivery system
US5326568A (en) * 1991-05-03 1994-07-05 Giampapa Vincent C Method of tissue-specific delivery
CA2071137A1 (en) * 1991-07-10 1993-01-11 Clarence C. Lee Composition and method for revitalizing scar tissue
US5270300A (en) * 1991-09-06 1993-12-14 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone
USRE38827E1 (en) 1994-07-27 2005-10-11 3M Innovative Properties Company Adhesive sealant composition
US5583114A (en) 1994-07-27 1996-12-10 Minnesota Mining And Manufacturing Company Adhesive sealant composition
US5660848A (en) * 1994-11-02 1997-08-26 The Population Council, Center For Biomedical Research Subdermally implantable device
US6107102A (en) * 1995-06-07 2000-08-22 Regents Of The University Of California Therapeutic microdevices and methods of making and using same
US6762336B1 (en) 1998-01-19 2004-07-13 The American National Red Cross Hemostatic sandwich bandage
DE19841698A1 (de) * 1998-09-11 2000-03-16 Curative Technologies Gmbh Wachstumsfaktor-enthaltende Zusammensetzung zur Heilung von Gewebeschäden
US6964685B2 (en) 1999-06-22 2005-11-15 The Brigham And Women's Hospital, Inc. Biologic replacement for fibrin clot
AU5754800A (en) * 1999-06-22 2001-01-09 Brigham And Women's Hospital Biologic replacement for fibrin clot for intra-articular use
US6534693B2 (en) * 2000-11-06 2003-03-18 Afmedica, Inc. Surgically implanted devices having reduced scar tissue formation
US20040241211A9 (en) * 2000-11-06 2004-12-02 Fischell Robert E. Devices and methods for reducing scar tissue formation
US20040018228A1 (en) * 2000-11-06 2004-01-29 Afmedica, Inc. Compositions and methods for reducing scar tissue formation
US6648911B1 (en) 2000-11-20 2003-11-18 Avantec Vascular Corporation Method and device for the treatment of vulnerable tissue site
GB0113697D0 (en) 2001-06-06 2001-07-25 Smith & Nephew Fixation devices for tissue repair
JP4777650B2 (ja) 2002-09-10 2011-09-21 アメリカン ナショナル レッド クロス 止血用包帯
EP2335650B1 (en) 2003-12-11 2012-10-03 Isto Technologies Inc. Particulate cartilage system
ES2432556T3 (es) 2004-08-04 2013-12-04 Evonik Corporation Métodos para fabricar dispositivos de suministro y sus dispositivos
JP5292533B2 (ja) 2005-08-26 2013-09-18 ジンマー・インコーポレイテッド インプラントおよび関節疾患の治療、置換および治療方法
AU2007208243B2 (en) 2006-01-25 2013-09-19 Children's Medical Center Corporation Methods and procedures for ligament repair
US8445009B2 (en) * 2006-08-04 2013-05-21 Stb, Ltd Processes for the production of solid dressings for treating wounded tissue
CA2664866C (en) 2006-09-28 2018-08-14 Children's Medical Center Coporation Methods and collagen products for tissue repair
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
EP2134297B1 (en) 2007-04-12 2017-03-08 Zimmer, Inc. Apparatus for tissue repair
US20090075891A1 (en) * 2007-08-06 2009-03-19 Macphee Martin Methods and dressings for sealing internal injuries
EP2222281B1 (en) 2007-12-20 2018-12-05 Evonik Corporation Process for preparing microparticles having a low residual solvent volume
US11484578B2 (en) 2012-02-01 2022-11-01 Children's Medical Center Corporation Biomaterial for articular cartilage maintenance and treatment of arthritis
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
EP2951193A4 (en) 2013-02-01 2017-03-01 Children's Medical Center Corporation Collagen scaffolds
US12599700B2 (en) 2013-02-01 2026-04-14 The Children's Medical Center Corporation System and methods for connective tissue repair using scaffolds
EP3785738B1 (en) 2016-07-06 2025-11-05 Children's Medical Center Corporation Indirect method of articular tissue repair

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4450150A (en) * 1973-05-17 1984-05-22 Arthur D. Little, Inc. Biodegradable, implantable drug delivery depots, and method for preparing and using the same
US4391797A (en) * 1977-01-05 1983-07-05 The Children's Hospital Medical Center Systems for the controlled release of macromolecules
SE416175B (sv) * 1979-03-07 1980-12-08 Per Ingvar Branemark For implantering i kroppsvevnad serskilt benvevnad, avsett material
US4529590A (en) * 1982-12-27 1985-07-16 Leveen Robert F Production of angiogenetic factor
US4503038A (en) * 1983-02-25 1985-03-05 The Regents Of The University Of California Extracellular nonmitogenic angiogenesis factor and method of isolation thereof from wound fluid
US4690682A (en) * 1983-04-15 1987-09-01 Damon Biotech, Inc. Sustained release
GB8330969D0 (en) * 1983-11-21 1983-12-29 Wellcome Found Promoting healing
IL74715A0 (en) * 1984-03-27 1985-06-30 Univ New Jersey Med Biodegradable matrix and methods for producing same
US4699788A (en) * 1984-08-20 1987-10-13 Trustees Of Boston University Angiogenic factor methods of extraction and method for producing angiogenesis
US4727137A (en) * 1985-04-17 1988-02-23 President And Fellows Of Harvard College Purified protein having angiogenic activity and methods of preparation
JPH0664019B2 (ja) * 1985-07-16 1994-08-22 株式会社日立製作所 画像表示処理装置
AU695983B3 (en) * 1997-09-19 1998-08-27 Badge Company (Proprietary) Limited, The Badge and method of making it

Also Published As

Publication number Publication date
AU1811788A (en) 1988-12-22
GR3004229T3 (cg-RX-API-DMAC10.html) 1993-03-31
EP0295721B1 (en) 1992-01-02
KR890000101A (ko) 1989-03-11
US4952403A (en) 1990-08-28
ES2027728T3 (es) 1992-06-16
PT87753B (pt) 1992-10-30
JPS6486974A (en) 1989-03-31
DK333788A (da) 1989-02-10
EP0295721A2 (en) 1988-12-21
JPH0311785B2 (cg-RX-API-DMAC10.html) 1991-02-18
DK333788D0 (da) 1988-06-17
AU605599B2 (en) 1991-01-17
PT87753A (pt) 1988-07-01
EP0295721A3 (en) 1989-02-01
DE3867328D1 (de) 1992-02-13
CA1326817C (en) 1994-02-08

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