KR900700458A - 4-아미노-3-아실 퀴놀린 유도체 및 이의 위산 분비 억제제로서의 용도 - Google Patents
4-아미노-3-아실 퀴놀린 유도체 및 이의 위산 분비 억제제로서의 용도Info
- Publication number
- KR900700458A KR900700458A KR1019890701952A KR890701952A KR900700458A KR 900700458 A KR900700458 A KR 900700458A KR 1019890701952 A KR1019890701952 A KR 1019890701952A KR 890701952 A KR890701952 A KR 890701952A KR 900700458 A KR900700458 A KR 900700458A
- Authority
- KR
- South Korea
- Prior art keywords
- amino
- 6alkyl
- gastric acid
- acid secretion
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888804443A GB8804443D0 (en) | 1988-02-25 | 1988-02-25 | Compounds |
| PCT/EP1989/000173 WO1989008105A1 (en) | 1988-02-25 | 1989-02-20 | 4-amino-3-acylquinoline derivatives and their use as inhibitors of gastric secretion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR900700458A true KR900700458A (ko) | 1990-08-13 |
Family
ID=10632375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019890701952A KR900700458A (ko) | 1988-02-25 | 1989-10-24 | 4-아미노-3-아실 퀴놀린 유도체 및 이의 위산 분비 억제제로서의 용도 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5143920A (pt) |
| EP (1) | EP0342775B1 (pt) |
| JP (1) | JPH02503316A (pt) |
| KR (1) | KR900700458A (pt) |
| CN (1) | CN1035663A (pt) |
| AT (1) | ATE94535T1 (pt) |
| AU (1) | AU3181789A (pt) |
| DE (1) | DE68909107T2 (pt) |
| DK (1) | DK528789A (pt) |
| FI (1) | FI895046A0 (pt) |
| GB (1) | GB8804443D0 (pt) |
| HU (1) | HU891462D0 (pt) |
| PT (1) | PT89788B (pt) |
| WO (1) | WO1989008105A1 (pt) |
| ZA (1) | ZA891389B (pt) |
| ZW (1) | ZW1889A1 (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8804444D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
| CA2011086A1 (en) * | 1989-03-17 | 1990-09-17 | Karl-Heinz Geiss | 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom |
| GB8918265D0 (en) * | 1989-08-10 | 1989-09-20 | Smithkline Beckman Intercredit | Compounds |
| WO1991014677A1 (fr) * | 1990-03-28 | 1991-10-03 | Otsuka Pharmaceutical Co., Ltd. | Derive de quinoline, medicament anti-ulcereux contenant ce derive et production de ce derive |
| FR2680510B1 (fr) * | 1991-08-20 | 1995-06-23 | Roussel Uclaf | Nouveaux derives bicycliques azotes, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant. |
| FR2672596B1 (fr) * | 1991-02-07 | 1995-07-13 | Roussel Uclaf | Nouveaux derives bicycliques azotes, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant. |
| MX9200299A (es) * | 1991-02-07 | 1992-12-01 | Roussel Uclaf | Nuevos derivados biciclicos nitrogenados, su procedimiento de preparacion los nuevos compuestos intermedios obtenidos su aplicacion como medicamentos y las composiciones farmaceuticas que los contienen. |
| GB9127252D0 (en) * | 1991-12-23 | 1992-02-19 | Boots Co Plc | Therapeutic agents |
| US5362743A (en) * | 1993-03-09 | 1994-11-08 | Pfizer Inc. | Aminoquinoline derivatives |
| US5556863A (en) * | 1993-06-11 | 1996-09-17 | Astra Aktiebolag | Compound for gastric acid secretion inhibition |
| IS4164A (is) * | 1993-06-11 | 1994-12-12 | Ab Astra | Efnasambönd sem hindra flæði magasýru |
| US5650415A (en) * | 1995-06-07 | 1997-07-22 | Sugen, Inc. | Quinoline compounds |
| BRPI9914164B8 (pt) | 1998-09-29 | 2021-05-25 | American Cyanamid Co | compostos de 3-ciano quinolina |
| WO2003093240A1 (en) * | 2002-04-30 | 2003-11-13 | Yungjin Pharmaceutical Co., Ltd. | Quinoline derivatives as caspase-3 inhibitor, preparation for producing the same and pharmaceutical composition comprising the same |
| FR2873695A1 (fr) * | 2004-07-30 | 2006-02-03 | Palumed Sa | Molecules hybrides qa ou q est une aminoquinoleine et a est un antibiotique ou un inhibiteur de resistance), leur synthese et leurs utilisations en tant qu'agent antibacterien |
| WO2019084271A1 (en) * | 2017-10-25 | 2019-05-02 | Children's Medical Center Corporation | PAPD5 INHIBITORS AND METHODS OF USE |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2652398A (en) * | 1949-11-17 | 1953-09-15 | Endo Products Inc | N-substituted-2-amino (methyl) quinolines |
| US3391146A (en) * | 1964-11-10 | 1968-07-02 | Bristol Myers Co | Nu-substituted carbamates and thiocarbamates of 2-quinolinemethanols |
| US3470186A (en) * | 1967-06-02 | 1969-09-30 | American Cyanamid Co | Substituted 4-anilino-3-quinolinecarboxylic acids and esters |
| CA942748A (en) * | 1970-09-18 | 1974-02-26 | Venkatachala L. Narayanan | 1-aziridinylcarbonyl substituted-3-quinolinecarboxylic acid compounds |
| US4343804A (en) * | 1979-03-26 | 1982-08-10 | A. H. Robins Company, Inc. | 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds |
| US4789678A (en) * | 1986-08-25 | 1988-12-06 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds |
| GB8621425D0 (en) * | 1986-09-05 | 1986-10-15 | Smith Kline French Lab | Compounds |
-
1988
- 1988-02-25 GB GB888804443A patent/GB8804443D0/en active Pending
-
1989
- 1989-02-20 AU AU31817/89A patent/AU3181789A/en not_active Abandoned
- 1989-02-20 WO PCT/EP1989/000173 patent/WO1989008105A1/en active Application Filing
- 1989-02-20 JP JP1502449A patent/JPH02503316A/ja active Pending
- 1989-02-20 HU HU891462A patent/HU891462D0/hu unknown
- 1989-02-20 ZW ZW18/89A patent/ZW1889A1/xx unknown
- 1989-02-22 PT PT89788A patent/PT89788B/pt not_active IP Right Cessation
- 1989-02-23 DE DE89301802T patent/DE68909107T2/de not_active Expired - Fee Related
- 1989-02-23 ZA ZA891389A patent/ZA891389B/xx unknown
- 1989-02-23 EP EP89301802A patent/EP0342775B1/en not_active Expired - Lifetime
- 1989-02-23 AT AT89301802T patent/ATE94535T1/de not_active IP Right Cessation
- 1989-02-23 US US07/314,684 patent/US5143920A/en not_active Expired - Fee Related
- 1989-02-24 CN CN89100928A patent/CN1035663A/zh active Pending
- 1989-10-24 KR KR1019890701952A patent/KR900700458A/ko not_active Application Discontinuation
- 1989-10-24 FI FI895046A patent/FI895046A0/fi not_active Application Discontinuation
- 1989-10-24 DK DK528789A patent/DK528789A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1989008105A1 (en) | 1989-09-08 |
| CN1035663A (zh) | 1989-09-20 |
| ATE94535T1 (de) | 1993-10-15 |
| PT89788A (pt) | 1989-10-04 |
| JPH02503316A (ja) | 1990-10-11 |
| HU891462D0 (en) | 1990-01-28 |
| DE68909107T2 (de) | 1994-02-17 |
| GB8804443D0 (en) | 1988-03-23 |
| AU3181789A (en) | 1989-09-22 |
| DK528789D0 (da) | 1989-10-24 |
| ZW1889A1 (en) | 1989-09-13 |
| ZA891389B (en) | 1990-10-31 |
| FI895046A0 (fi) | 1989-10-24 |
| DE68909107D1 (de) | 1993-10-21 |
| EP0342775A1 (en) | 1989-11-23 |
| DK528789A (da) | 1989-10-24 |
| EP0342775B1 (en) | 1993-09-15 |
| US5143920A (en) | 1992-09-01 |
| PT89788B (pt) | 1994-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |