KR900006559B1 - Crf 상사체의 재법 - Google Patents

Crf 상사체의 재법 Download PDF

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Publication number
KR900006559B1
KR900006559B1 KR1019840001956A KR840001956A KR900006559B1 KR 900006559 B1 KR900006559 B1 KR 900006559B1 KR 1019840001956 A KR1019840001956 A KR 1019840001956A KR 840001956 A KR840001956 A KR 840001956A KR 900006559 B1 KR900006559 B1 KR 900006559B1
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KR
South Korea
Prior art keywords
glu
leu
ala
gln
ser
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Expired
Application number
KR1019840001956A
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English (en)
Korean (ko)
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KR840009075A (ko
Inventor
에드워어드 프레드릭 리비어 지인
스피이 죠우아김
워어커 베일 쥬니어 와일리
Original Assignee
더 솔크 인스티튜트 훠 바이올로지칼 스터디이즈
델버어트 어니스트 그란즈
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Publication date
Application filed by 더 솔크 인스티튜트 훠 바이올로지칼 스터디이즈, 델버어트 어니스트 그란즈 filed Critical 더 솔크 인스티튜트 훠 바이올로지칼 스터디이즈
Publication of KR840009075A publication Critical patent/KR840009075A/ko
Application granted granted Critical
Publication of KR900006559B1 publication Critical patent/KR900006559B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57509—Corticotropin releasing factor [CRF] (Urotensin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2228—Corticotropin releasing factor [CRF] (Urotensin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Control Of Eletrric Generators (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Vehicle Body Suspensions (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Control Of El Displays (AREA)
KR1019840001956A 1983-04-14 1984-04-13 Crf 상사체의 재법 Expired KR900006559B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US484931 1983-04-14
US06/484,931 US4489163A (en) 1983-04-14 1983-04-14 rCRF and analogs

Publications (2)

Publication Number Publication Date
KR840009075A KR840009075A (ko) 1984-12-24
KR900006559B1 true KR900006559B1 (ko) 1990-09-13

Family

ID=23926236

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840001956A Expired KR900006559B1 (ko) 1983-04-14 1984-04-13 Crf 상사체의 재법

Country Status (16)

Country Link
US (1) US4489163A (https=)
EP (1) EP0122798B1 (https=)
JP (1) JPH0689034B2 (https=)
KR (1) KR900006559B1 (https=)
AT (1) ATE96807T1 (https=)
AU (1) AU565699B2 (https=)
CA (1) CA1247602A (https=)
DE (1) DE3486238T2 (https=)
DK (1) DK172682B1 (https=)
ES (1) ES8606406A1 (https=)
GR (1) GR81467B (https=)
IE (1) IE61617B1 (https=)
IL (1) IL71326A (https=)
NZ (1) NZ207779A (https=)
PH (1) PH23123A (https=)
ZA (1) ZA842460B (https=)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0518391A1 (en) * 1984-02-23 1992-12-16 The Salk Institute For Biological Studies CRF analogs
FR2567524B1 (fr) * 1984-07-10 1987-11-27 Sanofi Sa Procede de synthese de la somatocrinine en phase liquide et peptides intermediaires
US4801612A (en) * 1986-07-03 1989-01-31 Regents Of The University Of California Method of inhibiting inflammatory response
DE3703340A1 (de) * 1987-02-04 1988-08-18 Dirck Dr Med Oppermann Pharmazeutische zubereitung zur behandlung der herzinsuffizienz
IE64788B1 (en) 1988-06-21 1995-09-06 Salk Inst For Biological Studi CRF analogs
CA1341051C (en) * 1988-09-23 2000-07-11 Jean Edouard Frederic Rivier Crf antagonists
CA1340964C (en) * 1988-09-30 2000-04-18 Jean E. F. Rivier Crf analogs
US5278146A (en) * 1988-09-30 1994-01-11 The Salk Institute For Biological Studies CRF analogs
CA2002004A1 (en) * 1988-11-14 1990-05-14 Karl P. Lederis Fish crf
US5488033A (en) * 1989-07-28 1996-01-30 The Regents Of The University Of California Treatment to reduce edema
US5137871A (en) * 1989-07-28 1992-08-11 Regents Of The University Of California Treatment to reduce edema for brain and musculature injuries
DE3942925A1 (de) * 1989-12-23 1991-06-27 Swf Auto Electric Gmbh Elektrischer schalter, insbesondere blinkerschalter fuer kraftfahrzeuge
US5177060A (en) * 1990-01-09 1993-01-05 Regents Of The University Of California Anti-inflammatory peptides and treatment to inhibit vascular leakage in injured tissues
US5480869A (en) * 1990-01-09 1996-01-02 The Regents Of The University Of California Anti-inflammatory peptide analogs and treatment to inhibit vascular leakage in injured tissues
US5245009A (en) * 1990-03-23 1993-09-14 The Salk Institute For Biological Studies CRF antagonists
US5235036A (en) * 1991-05-31 1993-08-10 The Salk Institute For Biological Studies Crf analogs
US5374621A (en) * 1991-09-13 1994-12-20 Regents Of The University Of California Neurotensin method for inhibiting vascular leakage
US6495343B1 (en) 1993-06-18 2002-12-17 The Salk Institute For Biological Studies Cloning and recombinant production of CRF receptor(s)
US6638905B2 (en) * 1993-06-18 2003-10-28 The Salk Institute For Biological Studies Cloning and recombinant production of CFR receptor(s)
US5728545A (en) * 1993-06-18 1998-03-17 The Salk Institute Of Biological Studies Cloning and recombinant production of CRF receptor (S)
WO1996008265A1 (en) * 1994-09-12 1996-03-21 The Trustees Of The University Of Pennsylvania Corticotropin release inhibiting factor and methods of using same
US6039956A (en) * 1994-09-12 2000-03-21 Pennsylvania, Trustees Of The University Of, The Corticotropin release inhibiting factor and methods of using same for treating behavioral symptoms in an anxiety disorder
US6670140B2 (en) * 2001-03-06 2003-12-30 The Procter & Gamble Company Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors
US7141546B1 (en) 2001-08-01 2006-11-28 The Salk Institute For Biologicial Studies CRFR2 selective ligands
WO2003011823A2 (en) * 2001-08-01 2003-02-13 The Salk Institute For Biological Studies Crfr1 selective ligands
US20090035298A1 (en) * 2007-04-23 2009-02-05 Washington University In St. Louis Methods to treat alzheimer's disease or other amyloid beta accumulation associated disorders
RU2010148803A (ru) * 2008-04-30 2012-06-10 Ньютрон Роу (Bm) Способы применения кортикотропин-рилизинг фактора для лечения рака
CA2766322A1 (en) 2009-06-24 2010-12-29 Stephen Evans-Freke Methods of using corticotropin-releasing factor for the treatment of cancer
EP2654772B1 (en) 2010-12-22 2018-09-26 The Salk Institute for Biological Studies Cyclic crf antagonist peptides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR67608E (fr) * 1955-02-22 1958-03-14 Variateur de vitesse, notamment pour cycles
GB2016015B (en) 1978-01-22 1982-05-06 Hayashibara Co Method of preparing interferon and preparations containing interferon
US4244946A (en) 1979-06-11 1981-01-13 The Salk Institute For Biological Studies Water-soluble peptides affecting gonadal function
US4415558A (en) 1981-06-08 1983-11-15 The Salk Institute For Biological Studies CRF And analogs
DE3280392D1 (de) 1981-11-23 1992-03-26 University Patents Inc Steuerung der dna-sequenzen-transkription.
GB2118190B (en) * 1982-04-13 1985-05-01 Erba Farmitalia Peptides with sauvagine-like activity

Also Published As

Publication number Publication date
EP0122798A3 (en) 1986-09-03
ES8606406A1 (es) 1986-04-01
NZ207779A (en) 1988-04-29
DK169784D0 (da) 1984-03-27
IL71326A (en) 1987-11-30
IL71326A0 (en) 1984-06-29
US4489163A (en) 1984-12-18
EP0122798A2 (en) 1984-10-24
EP0122798B1 (en) 1993-11-03
IE61617B1 (en) 1994-11-16
JPS59199662A (ja) 1984-11-12
DE3486238D1 (de) 1993-12-09
AU565699B2 (en) 1987-09-24
KR840009075A (ko) 1984-12-24
DK169784A (da) 1984-10-15
CA1247602A (en) 1988-12-28
GR81467B (https=) 1984-12-11
AU2677784A (en) 1984-10-18
JPH0689034B2 (ja) 1994-11-09
IE840867L (en) 1984-10-14
ATE96807T1 (de) 1993-11-15
ES531585A0 (es) 1986-04-01
DE3486238T2 (de) 1994-03-03
ZA842460B (en) 1984-11-28
DK172682B1 (da) 1999-05-25
PH23123A (en) 1989-05-05

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