KR900006330A - 피롤로[3,2-e]피라졸로[1,5-a]피리미딘 유도체 및 이를 함유하는 약제 - Google Patents

피롤로[3,2-e]피라졸로[1,5-a]피리미딘 유도체 및 이를 함유하는 약제 Download PDF

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KR900006330A
KR900006330A KR1019890014585A KR890014585A KR900006330A KR 900006330 A KR900006330 A KR 900006330A KR 1019890014585 A KR1019890014585 A KR 1019890014585A KR 890014585 A KR890014585 A KR 890014585A KR 900006330 A KR900006330 A KR 900006330A
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South Korea
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group
substituent
hydrogen atom
pyrazolo
pyrrolo
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KR1019890014585A
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KR0137766B1 (ko
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미치히고 쯔지다니
겐이찌 기시이
마사또 이나주
도시히로 모리모또
요시아끼 모또끼
이찌로 마쯔오
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스즈끼 쯔네시
포-라 가세이 고오교 가부시끼 가이샤
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음

Description

피롤로[3,2-e]피라졸로[1,5-a]피리미딘 유도체 및 이를 함유하는 약제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (3)

  1. 일반식(I)로 표시되는 피롤로[3,2-e]피라졸로[1,5-a]피리미딘 유도체 또는 그의 염.
    상기식에서, R1및 R2는 각각 수소원자, 치환기를 가져도 좋은 직쇄 또는 분지알킬기, 치환기를 가져도 좋은 시클로알킬기 또는 페닐기, 또는 치환기를 가져도 좋은 복소환기를 나타내고, R3는 수소원자 또는 시아노기를 나타낸다.
  2. 일반식(I)로 표시되는 피롤로[3,2-e]피라졸로[1,5-a]피리미딘 유도체 또는 그의 염을 유효성분으로 함유하는 순환기계 질환치료제.
    상기식에서, R1및 R2는 각각 수소원자, 치환되어도 좋은 직쇄 또는 치환되어도 좋은 시클로알킬기 또는 페닐기, 또는 치환되어도 좋은 복소환기를 나타내며, R3는 수소원자 또는 시아노기를 나타낸다.
  3. 일반식(I)로 표시되는 피롤로[3,2-e]피라졸로[1,5-a]피리미딘 유도체를 유효성분으로 함유하는 기관지 확장증 치료제.
    상기 식중, R1및 R2는 각각 수소원자, 치환기를 가져도 좋은 직쇄 또는 분지알킬기, 치환기를 가져도 좋은 시클로알킬 또는 페닐기, 또는 치환기를 가져도 좋은 복소환기를 나타내며, R3는 수소원자 또는 시아노기를 나타낸다.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890014585A 1988-10-13 1989-10-11 피롤로[3,2-e] 피라졸로[1,5-a] 피리미딘 유도체 및 이를 함유하는 약제 KR0137766B1 (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
JP258084 1988-10-13
JP258084/1988 1988-10-13
JP25808488 1988-10-13
JP1155689 1989-01-20
JP11556/1989 1989-01-20
JP11555/1989 1989-01-20
JP1155589 1989-01-20
JP11556 1989-01-20
JP11555 1989-01-20

Publications (2)

Publication Number Publication Date
KR900006330A true KR900006330A (ko) 1990-05-07
KR0137766B1 KR0137766B1 (ko) 1998-05-15

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890014585A KR0137766B1 (ko) 1988-10-13 1989-10-11 피롤로[3,2-e] 피라졸로[1,5-a] 피리미딘 유도체 및 이를 함유하는 약제

Country Status (7)

Country Link
US (1) US4992442A (ko)
EP (1) EP0369145B1 (ko)
KR (1) KR0137766B1 (ko)
CN (1) CN1041943A (ko)
CA (1) CA1330079C (ko)
DE (1) DE68925270T2 (ko)
ES (1) ES2088882T3 (ko)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0276880A (ja) * 1988-06-16 1990-03-16 Sankyo Co Ltd 悪液質改善治療剤
JPH04307543A (ja) * 1991-04-04 1992-10-29 Konica Corp 新規な写真用カプラー
ATE194981T1 (de) * 1992-04-30 2000-08-15 Taiho Pharmaceutical Co Ltd Oxazolidinderivat und sein pharmazeutisch verträgliches salz
JPH10218881A (ja) * 1997-02-03 1998-08-18 Pola Chem Ind Inc 新規なピロロピラゾロピリミジン誘導体
US6329382B1 (en) * 1997-02-14 2001-12-11 Pola Chemical Industries, Inc. Pyrrolo[3,2-e]pyrazolo[1,5-a]pyrimidine remedies/preventives for respiratory diseases
EP1149835A4 (en) * 1999-01-29 2002-08-21 Sumitomo Chemical Co FAT ACCUMULATION INHIBITORS
TWI271406B (en) * 1999-12-13 2007-01-21 Eisai Co Ltd Tricyclic condensed heterocyclic compounds, preparation method of the same and pharmaceuticals comprising the same
US20020061897A1 (en) 2000-03-30 2002-05-23 Elliott Richard L. Neuropeptide Y antagonists
WO2001079198A1 (en) * 2000-04-18 2001-10-25 Agouron Pharmaceuticals, Inc. Pyrazoles for inhibiting protein kinase
DK1433480T3 (da) 2001-07-13 2011-04-11 Btg Internat Ltd Company Lægemiddel indeholdende pyrimidin-derivat
MXPA04010441A (es) * 2002-04-23 2005-02-14 Shionogi & Co Derivado de pirazolo[1,5-a]pirimidina e inhibidor de nad(p)h oxidasa que contiene el mismo.
US7329658B2 (en) * 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
US7176210B2 (en) * 2003-02-10 2007-02-13 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
KR101601994B1 (ko) 2008-04-15 2016-03-17 에자이 알앤드디 매니지먼트 가부시키가이샤 3-페닐피라졸로[5,1-ｂ]티아졸 화합물
BR112015022545A2 (pt) 2013-03-13 2017-07-18 Constellation Pharmaceuticals Inc compostos de pirazolo e os usos disso

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792533A (fr) * 1971-12-09 1973-06-08 Int Chem & Nuclear Corp Nouvelles pyrazolo (1,5a) pyrimidines et leur procede de preparation
JPH0276880A (ja) * 1988-06-16 1990-03-16 Sankyo Co Ltd 悪液質改善治療剤

Also Published As

Publication number Publication date
CN1041943A (zh) 1990-05-09
KR0137766B1 (ko) 1998-05-15
CA1330079C (en) 1994-06-07
DE68925270D1 (de) 1996-02-08
ES2088882T3 (es) 1996-10-01
EP0369145A2 (en) 1990-05-23
EP0369145A3 (en) 1991-07-17
DE68925270T2 (de) 1996-06-13
EP0369145B1 (en) 1995-12-27
US4992442A (en) 1991-02-12

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