ATE285771T1 - Diaminotrifluoromethylpyrimidinderivate enthaltende antikrebs-zusammensetzung - Google Patents
Diaminotrifluoromethylpyrimidinderivate enthaltende antikrebs-zusammensetzungInfo
- Publication number
- ATE285771T1 ATE285771T1 AT98905653T AT98905653T ATE285771T1 AT E285771 T1 ATE285771 T1 AT E285771T1 AT 98905653 T AT98905653 T AT 98905653T AT 98905653 T AT98905653 T AT 98905653T AT E285771 T1 ATE285771 T1 AT E285771T1
- Authority
- AT
- Austria
- Prior art keywords
- diaminotrifluoromethylpyrimidene
- derivatives
- composition containing
- group
- cancer composition
- Prior art date
Links
- 230000001093 anti-cancer Effects 0.000 title abstract 2
- UVPXDGMMAFWHMJ-UHFFFAOYSA-N 2-(trifluoromethyl)pyridine-3,4-diamine Chemical class NC1=CC=NC(C(F)(F)F)=C1N UVPXDGMMAFWHMJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 125000006254 cycloalkyl carbonyl group Chemical group 0.000 abstract 1
- -1 furancarbonyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6008397 | 1997-02-28 | ||
| PCT/JP1998/000776 WO1998037887A1 (en) | 1997-02-28 | 1998-02-26 | Anticancer composition comprising a diaminotrifluoromethylpyridine derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE285771T1 true ATE285771T1 (de) | 2005-01-15 |
Family
ID=13131845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98905653T ATE285771T1 (de) | 1997-02-28 | 1998-02-26 | Diaminotrifluoromethylpyrimidinderivate enthaltende antikrebs-zusammensetzung |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6197796B1 (de) |
| EP (1) | EP0971711B1 (de) |
| KR (1) | KR20000075769A (de) |
| CN (1) | CN1111407C (de) |
| AT (1) | ATE285771T1 (de) |
| AU (1) | AU731274B2 (de) |
| CA (1) | CA2280744A1 (de) |
| DE (1) | DE69828390T2 (de) |
| TW (1) | TW415843B (de) |
| WO (1) | WO1998037887A1 (de) |
| ZA (1) | ZA981430B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2266114C2 (ru) | 2000-01-31 | 2005-12-20 | Исихара Сангио Кайся, Лтд. | Средство для лечения и профилактики заболеваний системы органов пищеварения, содержащее производное диаминотрифторметилпиридина |
| JP4848092B2 (ja) | 2000-02-01 | 2011-12-28 | 石原産業株式会社 | ジアミノトリフルオロメチルピリジン誘導体を含有する肺不全の治療剤又は予防剤 |
| ATE305783T1 (de) | 2000-02-01 | 2005-10-15 | Ishihara Sangyo Kaisha | Verwendung von diaminotrifluoromethylpyridinderivaten für die prevention und behandlung von lebererkrankungen |
| US20070031415A1 (en) * | 2002-10-30 | 2007-02-08 | Tatsuo Kinashi | Regulation of interaction between rapl and rap1 |
| EP3919543A3 (de) | 2005-04-22 | 2022-03-16 | Mitsubishi Chemical Corporation | Aus einer biomassenressource gewonnenes polyester und herstellungsverfahren dafür |
| DE102008015424A1 (de) * | 2008-03-20 | 2009-09-24 | Beiersdorf Ag | Kühlende kosmetische oder dermatologische Zubereitungen mit einem Gehalt an (1R,2S,5R)-2-Isopropyl-5-methyl-N-(2-(pyridyn-2-yl)ethyl-cyclohexancarboxamid und/oder (1R,2S,5R)-N-(4-(Cyanomethyl)-phenyl)-2-isopropyl-5- methylcyclohexancarboxamid mit Menthoxypropandiol |
| JP5584518B2 (ja) | 2009-05-28 | 2014-09-03 | 石原産業株式会社 | ジアミノトリフルオロメチルピリジン誘導体を含有する抗ショック剤 |
| WO2020230876A1 (ja) | 2019-05-15 | 2020-11-19 | 石原産業株式会社 | Ｎ－（２－エチルスルホニルアミノ－５－トリフルオロメチル－３－ピリジル）シクロヘキサンカルボキサミド・一ナトリウム塩の無水和物結晶体 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5229403A (en) * | 1990-07-10 | 1993-07-20 | Ishihara Sangyo Kaisha Ltd. | Diaminotrifluoromethylpyridine derivatives and phospholipase A2 inhibitor containing them |
| DE69127595T2 (de) * | 1990-07-10 | 1998-01-22 | Ishihara Sangyo Kaisha | Diaminotrifluoromethylpyrimidinderivate, Verfahren zu ihrer Herstellung und diese enthaltende Phospholipase-A2-Inhibitoren |
-
1998
- 1998-02-20 ZA ZA981430A patent/ZA981430B/xx unknown
- 1998-02-20 TW TW087102406A patent/TW415843B/zh not_active IP Right Cessation
- 1998-02-26 CA CA002280744A patent/CA2280744A1/en not_active Abandoned
- 1998-02-26 DE DE69828390T patent/DE69828390T2/de not_active Expired - Lifetime
- 1998-02-26 EP EP98905653A patent/EP0971711B1/de not_active Expired - Lifetime
- 1998-02-26 AU AU61163/98A patent/AU731274B2/en not_active Ceased
- 1998-02-26 CN CN98802776A patent/CN1111407C/zh not_active Expired - Fee Related
- 1998-02-26 KR KR1019997007841A patent/KR20000075769A/ko not_active Ceased
- 1998-02-26 US US09/355,957 patent/US6197796B1/en not_active Expired - Lifetime
- 1998-02-26 WO PCT/JP1998/000776 patent/WO1998037887A1/en not_active Ceased
- 1998-02-26 AT AT98905653T patent/ATE285771T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU6116398A (en) | 1998-09-18 |
| AU731274B2 (en) | 2001-03-29 |
| ZA981430B (en) | 1998-08-24 |
| EP0971711A1 (de) | 2000-01-19 |
| CN1111407C (zh) | 2003-06-18 |
| WO1998037887A1 (en) | 1998-09-03 |
| DE69828390D1 (de) | 2005-02-03 |
| DE69828390T2 (de) | 2005-06-02 |
| KR20000075769A (ko) | 2000-12-26 |
| CN1248166A (zh) | 2000-03-22 |
| US6197796B1 (en) | 2001-03-06 |
| EP0971711B1 (de) | 2004-12-29 |
| TW415843B (en) | 2000-12-21 |
| CA2280744A1 (en) | 1998-09-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |