KR900003457B1 - 암민-지환식아민-백금 착화합물 및 항종양제 - Google Patents

암민-지환식아민-백금 착화합물 및 항종양제 Download PDF

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Publication number
KR900003457B1
KR900003457B1 KR1019870014490A KR870014490A KR900003457B1 KR 900003457 B1 KR900003457 B1 KR 900003457B1 KR 1019870014490 A KR1019870014490 A KR 1019870014490A KR 870014490 A KR870014490 A KR 870014490A KR 900003457 B1 KR900003457 B1 KR 900003457B1
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KR
South Korea
Prior art keywords
compound
platinum
mmol
ammine
solution
Prior art date
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Expired
Application number
KR1019870014490A
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English (en)
Korean (ko)
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KR880007552A (ko
Inventor
데쓰시 도따니
가쓰또시 아오노
야스꼬 아다찌
Original Assignee
시오노기세이야꾸 가부시끼가이샤
요시또시 가즈오
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Publication of KR880007552A publication Critical patent/KR880007552A/ko
Application granted granted Critical
Publication of KR900003457B1 publication Critical patent/KR900003457B1/ko
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00—Metallocenes
    • C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Catalysts (AREA)
KR1019870014490A 1986-12-18 1987-12-18 암민-지환식아민-백금 착화합물 및 항종양제 Expired KR900003457B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP61-303529 1986-12-18
JP30352986 1986-12-18
JP303529/86 1986-12-18

Publications (2)

Publication Number Publication Date
KR880007552A KR880007552A (ko) 1988-08-27
KR900003457B1 true KR900003457B1 (ko) 1990-05-19

Family

ID=17922086

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870014490A Expired KR900003457B1 (ko) 1986-12-18 1987-12-18 암민-지환식아민-백금 착화합물 및 항종양제

Country Status (8)

Country Link
US (1) US4902797A (enExample)
EP (1) EP0273315B1 (enExample)
KR (1) KR900003457B1 (enExample)
AT (1) ATE73814T1 (enExample)
CA (1) CA1327039C (enExample)
DE (1) DE3777583D1 (enExample)
ES (1) ES2032430T3 (enExample)
GR (1) GR3004629T3 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4970324A (en) * 1985-12-24 1990-11-13 Hoeschele James D Aminoalkyl-substituted azetidine platinum(II) complexes
JPH01294683A (ja) * 1988-02-04 1989-11-28 Kanebo Ltd 新規白金錯体および該化合物を有効成分とする抗腫瘍剤並びに該化合物製造用中間体
DE3834098A1 (de) * 1988-10-07 1990-04-19 Behringwerke Ag Cis-platin-komplexe mit einem 1,3-diaminopropan-derivat als liganden, verfahren zu ihrer herstellung und diese verbindung enthaltende pharmazeutische mittel
GB9502799D0 (en) * 1995-02-14 1995-04-05 Johnson Matthey Plc Improvements in platinum complexes
CZ288406B6 (en) * 1998-05-27 2001-06-13 Lachema Np Platinum complex of oxidation number II, process for preparing such complex, the complex functioning as medicament and pharmaceutical composition in which the complex is comprised
GB0011903D0 (en) * 2000-05-18 2000-07-05 Astrazeneca Ab Combination chemotherapy
US6806289B1 (en) * 2000-07-14 2004-10-19 Stephen J. Lippard Coordination complexes, and methods for preparing by combinatorial methods, assaying and using the same
EP1420775B1 (en) * 2001-08-23 2010-02-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Platinum complexes and their uses in therapy
JP2006504691A (ja) * 2002-09-11 2006-02-09 ボード オブ リージェンツ ザ ユニバーシティー オブ テキサス システム 生化学的調節と組合せた抗腫瘍剤としての白金錯体
ES2257178B1 (es) * 2004-09-30 2007-08-16 Universidad Autonoma De Madrid Compuestos de platino de formula trans-(ptc12(isopropilamina)(4-(hidroximetil)-piridina)) y trans-(ptc12(isopropilamina)(3-hidroximetil)-piridina y su aplicacion como farmaco antitumoral.
US8168661B2 (en) * 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8173686B2 (en) 2006-11-06 2012-05-08 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8178564B2 (en) * 2006-11-06 2012-05-15 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168662B1 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US20110033528A1 (en) * 2009-08-05 2011-02-10 Poniard Pharmaceuticals, Inc. Stabilized picoplatin oral dosage form
US20100260832A1 (en) * 2007-06-27 2010-10-14 Poniard Pharmaceuticals, Inc. Combination therapy for ovarian cancer
TW200916094A (en) * 2007-06-27 2009-04-16 Poniard Pharmaceuticals Inc Stabilized picoplatin dosage form
US20100310661A1 (en) * 2007-07-16 2010-12-09 Poniard Pharmaceuticals, Inc. Oral formulations for picoplatin
EP2249827A4 (en) * 2008-02-08 2012-05-30 Poniard Pharmaceuticals Inc USE OF PICOPLATIN AND CETUXIMAB IN THE TREATMENT OF COLORECTAL CANCER

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57123198A (en) * 1981-01-23 1982-07-31 Shionogi & Co Ltd Novel platinum complex
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes

Also Published As

Publication number Publication date
DE3777583D1 (de) 1992-04-23
US4902797A (en) 1990-02-20
GR3004629T3 (enExample) 1993-04-28
EP0273315A1 (en) 1988-07-06
CA1327039C (en) 1994-02-15
KR880007552A (ko) 1988-08-27
EP0273315B1 (en) 1992-03-18
ES2032430T3 (es) 1993-02-16
ATE73814T1 (de) 1992-04-15

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