DE3777583D1 - Ammine-n-heterocyclische platinkomplexe und antitumormittel. - Google Patents

Ammine-n-heterocyclische platinkomplexe und antitumormittel.

Info

Publication number
DE3777583D1
DE3777583D1 DE8787118819T DE3777583T DE3777583D1 DE 3777583 D1 DE3777583 D1 DE 3777583D1 DE 8787118819 T DE8787118819 T DE 8787118819T DE 3777583 T DE3777583 T DE 3777583T DE 3777583 D1 DE3777583 D1 DE 3777583D1
Authority
DE
Germany
Prior art keywords
ammine
heterocyclic
platinum complexes
alkyl
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787118819T
Other languages
English (en)
Inventor
Tetsushi Totani
Katsutoshi Aono
Yasuko Adachi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of DE3777583D1 publication Critical patent/DE3777583D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00—Metallocenes
    • C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic System
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
DE8787118819T 1986-12-18 1987-12-18 Ammine-n-heterocyclische platinkomplexe und antitumormittel. Expired - Fee Related DE3777583D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP30352986 1986-12-18

Publications (1)

Publication Number Publication Date
DE3777583D1 true DE3777583D1 (de) 1992-04-23

Family

ID=17922086

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787118819T Expired - Fee Related DE3777583D1 (de) 1986-12-18 1987-12-18 Ammine-n-heterocyclische platinkomplexe und antitumormittel.

Country Status (8)

Country Link
US (1) US4902797A (de)
EP (1) EP0273315B1 (de)
KR (1) KR900003457B1 (de)
AT (1) ATE73814T1 (de)
CA (1) CA1327039C (de)
DE (1) DE3777583D1 (de)
ES (1) ES2032430T3 (de)
GR (1) GR3004629T3 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4970324A (en) * 1985-12-24 1990-11-13 Hoeschele James D Aminoalkyl-substituted azetidine platinum(II) complexes
JPH01294683A (ja) * 1988-02-04 1989-11-28 Kanebo Ltd 新規白金錯体および該化合物を有効成分とする抗腫瘍剤並びに該化合物製造用中間体
DE3834098A1 (de) * 1988-10-07 1990-04-19 Behringwerke Ag Cis-platin-komplexe mit einem 1,3-diaminopropan-derivat als liganden, verfahren zu ihrer herstellung und diese verbindung enthaltende pharmazeutische mittel
GB9502799D0 (en) * 1995-02-14 1995-04-05 Johnson Matthey Plc Improvements in platinum complexes
CZ288406B6 (en) * 1998-05-27 2001-06-13 Lachema Np Platinum complex of oxidation number II, process for preparing such complex, the complex functioning as medicament and pharmaceutical composition in which the complex is comprised
GB0011903D0 (en) * 2000-05-18 2000-07-05 Astrazeneca Ab Combination chemotherapy
US6806289B1 (en) * 2000-07-14 2004-10-19 Stephen J. Lippard Coordination complexes, and methods for preparing by combinatorial methods, assaying and using the same
JP2005501859A (ja) * 2001-08-23 2005-01-20 イサム・リサーチ・デベロツプメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシテイ・オブ・エルサレム 白金錯体及びガンの処置におけるそれらの使用
US7271161B2 (en) * 2002-09-11 2007-09-18 Board Of Regents, The University Of Texas System Platinum complexes as antitumor agents in combination with biochemical modulation
ES2257178B1 (es) * 2004-09-30 2007-08-16 Universidad Autonoma De Madrid Compuestos de platino de formula trans-(ptc12(isopropilamina)(4-(hidroximetil)-piridina)) y trans-(ptc12(isopropilamina)(3-hidroximetil)-piridina y su aplicacion como farmaco antitumoral.
US8168662B1 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8178564B2 (en) * 2006-11-06 2012-05-15 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8173686B2 (en) 2006-11-06 2012-05-08 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168661B2 (en) * 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US20110033528A1 (en) * 2009-08-05 2011-02-10 Poniard Pharmaceuticals, Inc. Stabilized picoplatin oral dosage form
US20100260832A1 (en) * 2007-06-27 2010-10-14 Poniard Pharmaceuticals, Inc. Combination therapy for ovarian cancer
TW200916094A (en) * 2007-06-27 2009-04-16 Poniard Pharmaceuticals Inc Stabilized picoplatin dosage form
EP2178893A4 (de) * 2007-07-16 2012-09-19 Poniard Pharmaceuticals Inc Orale formulierungen für picoplatin
CA2715353A1 (en) * 2008-02-08 2009-08-13 Poniard Pharmaceuticals, Inc. Use of picoplatin and cetuximab to treat colorectal cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57123198A (en) * 1981-01-23 1982-07-31 Shionogi & Co Ltd Novel platinum complex
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes

Also Published As

Publication number Publication date
US4902797A (en) 1990-02-20
CA1327039C (en) 1994-02-15
KR900003457B1 (ko) 1990-05-19
KR880007552A (ko) 1988-08-27
GR3004629T3 (de) 1993-04-28
EP0273315A1 (de) 1988-07-06
EP0273315B1 (de) 1992-03-18
ATE73814T1 (de) 1992-04-15
ES2032430T3 (es) 1993-02-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee