KR900001650A - 치환된 구아닐티오우레아의 제조방법 - Google Patents

치환된 구아닐티오우레아의 제조방법 Download PDF

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Publication number
KR900001650A
KR900001650A KR1019890010276A KR890010276A KR900001650A KR 900001650 A KR900001650 A KR 900001650A KR 1019890010276 A KR1019890010276 A KR 1019890010276A KR 890010276 A KR890010276 A KR 890010276A KR 900001650 A KR900001650 A KR 900001650A
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KR
South Korea
Prior art keywords
formula
carbon atoms
guanylthiourea
reaction
alkyl
Prior art date
Application number
KR1019890010276A
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English (en)
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KR920000375B1 (ko
Inventor
알란 라이터 로우렌스
Original Assignee
윌리암 데이비스 현
화이자 인코포레이티드
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Application filed by 윌리암 데이비스 현, 화이자 인코포레이티드 filed Critical 윌리암 데이비스 현
Publication of KR900001650A publication Critical patent/KR900001650A/ko
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Publication of KR920000375B1 publication Critical patent/KR920000375B1/ko

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/24Derivatives of thiourea containing any of the groups, X being a hetero atom, Y being any atom
    • C07C335/28Y being a hetero atom, e.g. thiobiuret
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/40Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

Abstract

내용 없음.

Description

치환된 구아닐티오우레아의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 하기 일반식(A)의 S-알킬디티오비우렛티움을 반응-불활성 용매중에서 적어도 1몰 당량의 하기 일반식(B)의 아민과 함께 가열시킴을 포함하는 하기 일반식(Ⅱ)의 화합물의 제조방법.
    상기식에서, R은 탄소수 1 내지 6의 알킬 또는 벤질이고, R1은 탄소수 1 내지 3의 알킬이다.
  2. 제1항에 있어서, R이 n-펜틸이고, R1이 메틸인 방법.
  3. 제2항에 있어서, 상기 반응-불활성 용매가 탄소수 1 내지 3의 알칸올인 방법.
  4. 제3항에 있어서, 상기 반응-불활성 용매가 i-프로판올인 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890010276A 1988-07-21 1989-07-20 치환된 구아닐티오우레아의 제조방법 KR920000375B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22313288A 1988-07-21 1988-07-21
US223,132 1988-07-21

Publications (2)

Publication Number Publication Date
KR900001650A true KR900001650A (ko) 1990-02-27
KR920000375B1 KR920000375B1 (ko) 1992-01-13

Family

ID=22835175

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890010276A KR920000375B1 (ko) 1988-07-21 1989-07-20 치환된 구아닐티오우레아의 제조방법

Country Status (18)

Country Link
EP (1) EP0357192B1 (ko)
JP (1) JPH0273055A (ko)
KR (1) KR920000375B1 (ko)
AT (1) ATE75730T1 (ko)
AU (1) AU598714B2 (ko)
CA (1) CA1316940C (ko)
DE (1) DE68901431D1 (ko)
DK (1) DK170470B1 (ko)
ES (1) ES2030974T3 (ko)
FI (1) FI893505A (ko)
GR (1) GR3004520T3 (ko)
HU (1) HU201909B (ko)
IE (1) IE60446B1 (ko)
IL (1) IL90953A0 (ko)
NO (1) NO169649C (ko)
NZ (1) NZ230004A (ko)
PT (1) PT91217B (ko)
ZA (1) ZA895526B (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6686350B1 (en) 1996-07-25 2004-02-03 Biogen, Inc. Cell adhesion inhibitors
KR100720907B1 (ko) 1999-08-13 2007-05-25 바이오겐 아이덱 엠에이 인코포레이티드 세포 유착 억제제
US7196112B2 (en) 2004-07-16 2007-03-27 Biogen Idec Ma Inc. Cell adhesion inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4560690A (en) * 1984-04-30 1985-12-24 Pfizer Inc. 2-(N-substituted guanidino)-4-hetero-arylthiazole antiulcer agents

Also Published As

Publication number Publication date
FI893505A (fi) 1990-01-22
NO892973D0 (no) 1989-07-20
GR3004520T3 (ko) 1993-04-28
DE68901431D1 (de) 1992-06-11
IL90953A0 (en) 1990-02-09
PT91217B (pt) 1995-03-01
FI893505A0 (fi) 1989-07-20
IE892355L (en) 1990-01-21
PT91217A (pt) 1990-02-08
JPH0273055A (ja) 1990-03-13
KR920000375B1 (ko) 1992-01-13
NO169649C (no) 1992-07-22
ZA895526B (en) 1991-03-27
AU3882889A (en) 1990-01-25
AU598714B2 (en) 1990-06-28
NO169649B (no) 1992-04-13
HU201909B (en) 1991-01-28
ES2030974T3 (es) 1992-11-16
IE60446B1 (en) 1994-07-13
EP0357192A1 (en) 1990-03-07
ATE75730T1 (de) 1992-05-15
DK359589D0 (da) 1989-07-20
NZ230004A (en) 1990-07-26
JPH0585545B2 (ko) 1993-12-07
DK359589A (da) 1990-01-22
HUT50760A (en) 1990-03-28
EP0357192B1 (en) 1992-05-06
CA1316940C (en) 1993-04-27
NO892973L (no) 1990-01-22
DK170470B1 (da) 1995-09-11

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