KR890006706A - 무수물 공중합체 및 그의 제조방법 - Google Patents

무수물 공중합체 및 그의 제조방법 Download PDF

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Publication number
KR890006706A
KR890006706A KR1019870011521A KR870011521A KR890006706A KR 890006706 A KR890006706 A KR 890006706A KR 1019870011521 A KR1019870011521 A KR 1019870011521A KR 870011521 A KR870011521 A KR 870011521A KR 890006706 A KR890006706 A KR 890006706A
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South Korea
Prior art keywords
prepolymer
copolymer
anhydride
separately
acetic anhydride
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KR1019870011521A
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English (en)
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KR960006410B1 (ko
Inventor
제이. 돔 아브라함
에스. 랑거 로버어트
Original Assignee
죤 티. 프레스톤
매사츄세츠 인스티튜트 오브 테크놀로지
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25444276&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR890006706(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 죤 티. 프레스톤, 매사츄세츠 인스티튜트 오브 테크놀로지 filed Critical 죤 티. 프레스톤
Publication of KR890006706A publication Critical patent/KR890006706A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G67/00—Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing oxygen or oxygen and carbon, not provided for in groups C08G2/00 - C08G65/00
    • C08G67/04—Polyanhydrides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Polyethers (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

내용 없음

Description

무수물 공중합체 및 그의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제 1 도는 본발명에 의한 순수한 무수물 공중합체의 합성을 표시하고,
제 2 도는 종래방법에 의한 무수물 공중합체의 합성을 표시한다.

Claims (6)

  1. 적어도 두 2가산을 선정하여 개별적으로 합성, 정제하고, 각 2가산과 무수 아세트산을 별도로 반응시켜 프리폴리머를 형성하고, 무수 아세트산과 상기 2가산과의 반응에 의해 생성된 각 프리폴리머를 별도로 재결정시키고, 특정 비율로 상기 각 프리폴리머들을 조합하고, 상기 프리폴리머 혼합물을 중합하여 공중합체를 형성하는 단계로 되어 있는 것을 특징으로 하는 고순도 무수물 공중합체의 제조방법.
  2. 제1항에 있어서, 2가산이 세바스산, 비스(P-카르복시페녹시)프로판, 비스(P-카르복시페녹시)헥산, 이소프탈산, 1.4페닐렌 디프로피온산, 아디프산 및 도데칸디오산으로 구성된 군에서 선택되는 것을 특징으로하는 방법.
  3. 지방족과 방향족 2가산으로 구성된 군에서 선택된 단량체로 돠어 있으며, 공중합체가 무수아세트산과 별도로 반응된 각 단량체의 일정비율의 프리폴리머들의 혼합물로부터 중합되는 것을 특징으로 하는 고순도무수물 공중합체.
  4. 제3항에서 있어서, 상기 프리폴리머가 개별적 프리폴리머를 형성하기 위해 각 단량체를 무수 아세트산과 별도로 환류시키고, 과잉의 무수 아세트산을 제거하고, 그리고 프리폴리머를 재결정시키는 단계에 의해 형성되는 것을 특징으로 하는 무수물 공중합체.
  5. 제3항에 있어서, 공중합체가 재결정화에 의해 더욱 정제되는 것을 특징으로 하는 무수물 공중합체.
  6. 제3항에 있어서, 상기 공중합체가 촉매의 존재하에 상기 프리폴리머로 부터 중합되는 것을 특징으로하는 무수물 공중합체.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019870011521A 1986-10-17 1987-10-17 무수물 공중합체 및 그의 제조방법 KR960006410B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US920,724 1986-10-17
US06/920,724 US4789724A (en) 1986-10-17 1986-10-17 Preparation of anhydride copolymers
US86920724 1987-10-17

Publications (2)

Publication Number Publication Date
KR890006706A true KR890006706A (ko) 1989-06-15
KR960006410B1 KR960006410B1 (ko) 1996-05-15

Family

ID=25444276

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870011521A KR960006410B1 (ko) 1986-10-17 1987-10-17 무수물 공중합체 및 그의 제조방법

Country Status (7)

Country Link
US (1) US4789724A (ko)
EP (2) EP0266603A1 (ko)
JP (1) JP2626717B2 (ko)
KR (1) KR960006410B1 (ko)
AT (1) ATE285432T1 (ko)
CA (1) CA1278141C (ko)
DE (2) DE3752381T2 (ko)

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JP2626717B2 (ja) 1997-07-02
CA1278141C (en) 1990-12-18
EP0266603A1 (en) 1988-05-11
ATE285432T1 (de) 2005-01-15
DE3752381D1 (de) 2005-01-27
EP0692510B1 (en) 2004-12-22
JPS63199227A (ja) 1988-08-17
DE3752381T2 (de) 2005-11-10
KR960006410B1 (ko) 1996-05-15
US4789724A (en) 1988-12-06
DE266603T1 (de) 1989-02-16
EP0692510A1 (en) 1996-01-17

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