KR890006609A - 술파모일-2-벤조푸란카르복실산 유도체 - Google Patents

술파모일-2-벤조푸란카르복실산 유도체 Download PDF

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Publication number
KR890006609A
KR890006609A KR1019880013319A KR880013319A KR890006609A KR 890006609 A KR890006609 A KR 890006609A KR 1019880013319 A KR1019880013319 A KR 1019880013319A KR 880013319 A KR880013319 A KR 880013319A KR 890006609 A KR890006609 A KR 890006609A
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KR
South Korea
Prior art keywords
benzofurancarboxylic acid
dimethylsulfamoyl
dichloro
compound
hydrogen
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KR1019880013319A
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English (en)
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KR960011383B1 (ko
Inventor
히로시 하라다
요시히로 마쯔시따
마즈히사 나까무라
유끼오 요네따니
Original Assignee
요시또시 가즈오
시오노기 세이야꾸 가부시끼 가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 요시또시 가즈오, 시오노기 세이야꾸 가부시끼 가이샤 filed Critical 요시또시 가즈오
Publication of KR890006609A publication Critical patent/KR890006609A/ko
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Publication of KR960011383B1 publication Critical patent/KR960011383B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Diabetes (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

내용 없음

Description

술파모일-2-벤조푸란카르복실산 유도체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (7)

  1. 하기 일반식의 화합물:
    (상기식 중, R은 수소 및 보호기이고; R1및 R2는 동일 또는 상이하며 각각 수소, 저급 알킬기, 4-내지 7-원 시클로 알킬, 임의로 치환된 페닐, 페닐-저급 알킬, 저급 알콕시 카르보닐, 또는 모르폴리노 저급 알킬이거나, R1및 R2는 인접한 질소 원자와 함께 추가로 하나 또는 그 이상의 헤테로 원자를 가질 수 있는 임의 치환된 5- 또는 6-원 헤테로 사이클을 형성할 수 있으며; X 및 X'는 각각 수소 또는 할로겐이다.
  2. 제1항에 있어서, 6,7-디클로로-5-(N,N-디메틸술파모일)-2-벤조푸란카르복실산인 화합물.
  3. 제1항에 있어서, 6,7-디클로로-5-(N,N-디메틸술파모일)-2-벤조푸란카르복실산인 화합물.
  4. 제1항에 있어서, 6,7-디클로로-5-(N,N-디메틸술파모일)-2-벤조푸란카르복실산인 화합물.
  5. 제1항에 있어서, 6,7-디클로로-5-(N,N-디메틸술파모일)-2-벤조푸란카르복실산인 화합물.
  6. 제1항에 있어서, 6,7-디클로로-5-(N,N-디메틸술파모일)-2-벤조푸란카르복실산인 화합물.
  7. 제1항에 있어서, 6,7-디클로로-5-(N,N-디메틸술파모일)-2-벤조푸란카르복실산인 화합물.
KR1019880013319A 1987-10-12 1988-10-12 술파모일-2-벤조푸란카르복실산 유도체 KR960011383B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP62256890A JPH01100164A (ja) 1987-10-12 1987-10-12 スルファモイル−２−ベンゾフランカルボン酸誘導体
JP256890/1987 1987-10-12
JP62-256890 1987-10-12

Publications (2)

Publication Number Publication Date
KR890006609A true KR890006609A (ko) 1989-06-14
KR960011383B1 KR960011383B1 (ko) 1996-08-22

Family

ID=17298833

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880013319A KR960011383B1 (ko) 1987-10-12 1988-10-12 술파모일-2-벤조푸란카르복실산 유도체

Country Status (9)

Country Link
US (1) US4918206A (ko)
EP (1) EP0312338B1 (ko)
JP (1) JPH01100164A (ko)
KR (1) KR960011383B1 (ko)
AT (1) ATE70834T1 (ko)
CA (1) CA1333603C (ko)
DE (1) DE3867202D1 (ko)
ES (1) ES2039282T3 (ko)
GR (1) GR3003762T3 (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170095269A (ko) * 2014-12-10 2017-08-22 트리시다, 인크. 경구 투여용 양성자-결합 폴리머

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5387681A (en) * 1992-08-19 1995-02-07 Eli Lilly And Company Synthesis of bicyclic aromatic sulfonic acids sulfonyl chlorides and sulfonamides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4085117A (en) * 1976-10-18 1978-04-18 Merck & Co., Inc. 6,7-Disubstituted-5-(acyl)benzofuran-2-carboxylic acids
US4663347A (en) * 1983-10-31 1987-05-05 Merck Frosst Canada, Inc. Benzofuran 2-carboxylic acid esters useful as inhibitors of leukotriene biosynthesis
JPS6163671A (ja) * 1984-09-05 1986-04-01 Shionogi & Co Ltd ２，３−ジヒドロベンゾフラン−５−スルホンアミド誘導体および降圧利尿剤
ES8705871A1 (es) * 1984-12-29 1987-05-16 Kaken Pharma Co Ltd Un procedimiento para preparar un derivado de benzofurano
JP3095505B2 (ja) * 1992-01-31 2000-10-03 沖電気工業株式会社 画像形成装置

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170095269A (ko) * 2014-12-10 2017-08-22 트리시다, 인크. 경구 투여용 양성자-결합 폴리머

Also Published As

Publication number Publication date
CA1333603C (en) 1994-12-20
EP0312338B1 (en) 1991-12-27
KR960011383B1 (ko) 1996-08-22
ATE70834T1 (de) 1992-01-15
EP0312338A1 (en) 1989-04-19
DE3867202D1 (de) 1992-02-06
JPH01100164A (ja) 1989-04-18
GR3003762T3 (ko) 1993-03-16
US4918206A (en) 1990-04-17
JPH0579069B2 (ko) 1993-11-01
ES2039282T3 (es) 1996-07-16

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