ATE237592T1 - Akridinium derivate und deren konjugate - Google Patents
Akridinium derivate und deren konjugateInfo
- Publication number
- ATE237592T1 ATE237592T1 AT94101664T AT94101664T ATE237592T1 AT E237592 T1 ATE237592 T1 AT E237592T1 AT 94101664 T AT94101664 T AT 94101664T AT 94101664 T AT94101664 T AT 94101664T AT E237592 T1 ATE237592 T1 AT E237592T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- specific binding
- acridinium compounds
- activity
- conjugates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP01746593A JP3584379B2 (ja) | 1993-02-04 | 1993-02-04 | アクリジニウム化合物およびアクリジニウム化合物複合体 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE237592T1 true ATE237592T1 (de) | 2003-05-15 |
Family
ID=11944776
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94101664T ATE237592T1 (de) | 1993-02-04 | 1994-02-03 | Akridinium derivate und deren konjugate |
Country Status (7)
Country | Link |
---|---|
US (2) | US5438139A (de) |
EP (1) | EP0609885B1 (de) |
JP (1) | JP3584379B2 (de) |
AT (1) | ATE237592T1 (de) |
CA (1) | CA2114754A1 (de) |
DE (1) | DE69432497T2 (de) |
ES (1) | ES2196012T3 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6414152B1 (en) * | 1981-12-11 | 2002-07-02 | University Of Wales College Of Medicine Of Heath Park | Luminescent labelling material and procedures |
US7122671B1 (en) * | 1979-07-19 | 2006-10-17 | University College Cardiff Consultants Limited | Luminescent labelling materials and procedures |
ES2063735T3 (es) * | 1986-10-22 | 1995-01-16 | Abbott Lab | Sales de acridinio quimioluminiscentes. |
US5656426A (en) * | 1988-08-01 | 1997-08-12 | Chiron Diagnostics Corporation | Functionaized hydrophilic acridinium esters |
US5593845A (en) * | 1993-05-17 | 1997-01-14 | Lumigen, Inc. | Aryl N-alkylacridancarboxylate derivatives useful for chemiluminescent detection |
GB2282222A (en) * | 1993-09-09 | 1995-03-29 | Univ Nottingham | Detecting genetic material using labelled DNA |
GB2289334B (en) * | 1994-05-10 | 1998-08-26 | Molecular Light Technology Lim | Enzyme linked chemiluminescent assay |
US5731148A (en) * | 1995-06-07 | 1998-03-24 | Gen-Probe Incorporated | Adduct protection assay |
EP0761652A1 (de) * | 1995-08-01 | 1997-03-12 | Mochida Pharmaceutical Co., Ltd. | Acridiniumverbindung mit mehreren lumineszierenden Gruppen und Bindungsgruppen und Konjugate derselben |
US6165800A (en) * | 1997-05-30 | 2000-12-26 | Bayer Corporation | Chemiluminescent energy transfer conjugates and their uses as labels in binding assays |
AU9110698A (en) * | 1997-08-21 | 1999-03-08 | Capricorn Products, Inc. | Peroxide-based chemiluminescent assays and chemiluminescent compounds used ther ein |
WO2000009487A1 (en) | 1998-08-11 | 2000-02-24 | Bayer Corporation | Near infrared chemiluminescent acridinium compounds and uses thereof |
US6673560B1 (en) | 1998-11-25 | 2004-01-06 | Bayer Corporation | Measurement of hydride using chemiluminescent acridinium compounds and applications thereof |
US6723851B2 (en) | 2001-10-31 | 2004-04-20 | Quest Diagnostics Investment Incorporated | Chemiluminescent compounds and use thereof |
GB0320236D0 (en) * | 2003-08-29 | 2003-10-01 | Molecular Light Tech Res Ltd | Chemiluminescent compounds |
US8119422B2 (en) * | 2006-10-13 | 2012-02-21 | Siemens Healthcare Diagnostics Inc. | Stable acridinium esters with fast light emission |
JP5395803B2 (ja) * | 2007-11-20 | 2014-01-22 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッド | イオン液体中でのアクリジン化合物の容易なn−アルキル化 |
EP4010484A4 (de) * | 2019-08-07 | 2024-02-07 | MGI Holdings Co., Limited | Acridinium-esterhaltige verbindungen und verfahren zu deren verwendung zur chemilumineszenz-basierten einfarbensequenzierung |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4745181A (en) * | 1986-10-06 | 1988-05-17 | Ciba Corning Diagnostics Corp. | Polysubstituted aryl acridinium esters |
US5110932A (en) * | 1986-10-06 | 1992-05-05 | Ciba Corning Diagnostics Corp. | Polysubstituted aryl acridinium esters |
US4918192A (en) * | 1986-10-06 | 1990-04-17 | Ciba Corning Diagnostics Corp. | Polysubstituted aryl acridinium esters |
US5151518A (en) * | 1987-10-02 | 1992-09-29 | Abbott Laboratories | N-arylation of isatins |
NL8703075A (nl) * | 1987-12-18 | 1989-07-17 | Nederlanden Staat | Acridiniumverbindingen als chemiluminescentie-merkstof. |
NZ227506A (en) * | 1987-12-31 | 1992-06-25 | London Diagnostics Inc | Specific binding assays using chemiluminescent compounds |
US5290936A (en) * | 1987-12-31 | 1994-03-01 | London Diagnostics, Inc. | Nitro substituted chemiluminescent labels and their conjugates, and assays therefrom |
US5321136A (en) * | 1987-12-31 | 1994-06-14 | London Diagnostics, Inc. | Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom |
US4950613A (en) * | 1988-02-26 | 1990-08-21 | Gen-Probe Incorporated | Proteted chemiluminescent labels |
US5227489A (en) * | 1988-08-01 | 1993-07-13 | Ciba Corning Diagnostics Corp. | Stable hydrophilic acridinium esters suitable for liposome encapsulation |
US5241070A (en) * | 1988-09-26 | 1993-08-31 | Ciba Corning Diagnostics Corp. | Nucleophilic polysubstituted aryl acridinium esters and uses thereof |
-
1993
- 1993-02-04 JP JP01746593A patent/JP3584379B2/ja not_active Expired - Fee Related
-
1994
- 1994-01-31 US US08/188,724 patent/US5438139A/en not_active Expired - Fee Related
- 1994-02-02 CA CA002114754A patent/CA2114754A1/en not_active Abandoned
- 1994-02-03 DE DE69432497T patent/DE69432497T2/de not_active Expired - Fee Related
- 1994-02-03 AT AT94101664T patent/ATE237592T1/de not_active IP Right Cessation
- 1994-02-03 ES ES94101664T patent/ES2196012T3/es not_active Expired - Lifetime
- 1994-02-03 EP EP94101664A patent/EP0609885B1/de not_active Expired - Lifetime
-
1995
- 1995-04-28 US US08/430,866 patent/US5594112A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69432497T2 (de) | 2003-10-30 |
US5594112A (en) | 1997-01-14 |
JP3584379B2 (ja) | 2004-11-04 |
EP0609885B1 (de) | 2003-04-16 |
JPH06228102A (ja) | 1994-08-16 |
US5438139A (en) | 1995-08-01 |
CA2114754A1 (en) | 1994-08-05 |
DE69432497D1 (de) | 2003-05-22 |
ES2196012T3 (es) | 2003-12-16 |
EP0609885A1 (de) | 1994-08-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0609885 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |