ATE237592T1 - Akridinium derivate und deren konjugate - Google Patents

Akridinium derivate und deren konjugate

Info

Publication number
ATE237592T1
ATE237592T1 AT94101664T AT94101664T ATE237592T1 AT E237592 T1 ATE237592 T1 AT E237592T1 AT 94101664 T AT94101664 T AT 94101664T AT 94101664 T AT94101664 T AT 94101664T AT E237592 T1 ATE237592 T1 AT E237592T1
Authority
AT
Austria
Prior art keywords
group
specific binding
acridinium compounds
activity
conjugates
Prior art date
Application number
AT94101664T
Other languages
English (en)
Inventor
Naofumi Sato
Hiroshi Mochizuki
Toshinori Kanamori
Original Assignee
Mochida Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharm Co Ltd filed Critical Mochida Pharm Co Ltd
Application granted granted Critical
Publication of ATE237592T1 publication Critical patent/ATE237592T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
  • Luminescent Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT94101664T 1993-02-04 1994-02-03 Akridinium derivate und deren konjugate ATE237592T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP01746593A JP3584379B2 (ja) 1993-02-04 1993-02-04 アクリジニウム化合物およびアクリジニウム化合物複合体

Publications (1)

Publication Number Publication Date
ATE237592T1 true ATE237592T1 (de) 2003-05-15

Family

ID=11944776

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94101664T ATE237592T1 (de) 1993-02-04 1994-02-03 Akridinium derivate und deren konjugate

Country Status (7)

Country Link
US (2) US5438139A (de)
EP (1) EP0609885B1 (de)
JP (1) JP3584379B2 (de)
AT (1) ATE237592T1 (de)
CA (1) CA2114754A1 (de)
DE (1) DE69432497T2 (de)
ES (1) ES2196012T3 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6414152B1 (en) * 1981-12-11 2002-07-02 University Of Wales College Of Medicine Of Heath Park Luminescent labelling material and procedures
US7122671B1 (en) * 1979-07-19 2006-10-17 University College Cardiff Consultants Limited Luminescent labelling materials and procedures
ATE111083T1 (de) * 1986-10-22 1994-09-15 Abbott Lab Chemilumineszierende acridinium- und phenantridiniumsalze.
US5656426A (en) * 1988-08-01 1997-08-12 Chiron Diagnostics Corporation Functionaized hydrophilic acridinium esters
US5593845A (en) * 1993-05-17 1997-01-14 Lumigen, Inc. Aryl N-alkylacridancarboxylate derivatives useful for chemiluminescent detection
GB2282222A (en) * 1993-09-09 1995-03-29 Univ Nottingham Detecting genetic material using labelled DNA
GB2289334B (en) * 1994-05-10 1998-08-26 Molecular Light Technology Lim Enzyme linked chemiluminescent assay
US5731148A (en) * 1995-06-07 1998-03-24 Gen-Probe Incorporated Adduct protection assay
EP0761652A1 (de) * 1995-08-01 1997-03-12 Mochida Pharmaceutical Co., Ltd. Acridiniumverbindung mit mehreren lumineszierenden Gruppen und Bindungsgruppen und Konjugate derselben
US6165800A (en) * 1997-05-30 2000-12-26 Bayer Corporation Chemiluminescent energy transfer conjugates and their uses as labels in binding assays
EP1019379B1 (de) * 1997-08-21 2005-10-19 Maine Medical Center Auf peroxiden basierender chemilumineszenztest und chemilumineszente verbindungen die in diesem benutzt werden
AU5473999A (en) 1998-08-11 2000-03-06 Bayer Corporation Near infrared chemiluminescent acridinium compounds and uses thereof
US6673560B1 (en) 1998-11-25 2004-01-06 Bayer Corporation Measurement of hydride using chemiluminescent acridinium compounds and applications thereof
US6723851B2 (en) 2001-10-31 2004-04-20 Quest Diagnostics Investment Incorporated Chemiluminescent compounds and use thereof
GB0320236D0 (en) * 2003-08-29 2003-10-01 Molecular Light Tech Res Ltd Chemiluminescent compounds
JP5503969B2 (ja) * 2006-10-13 2014-05-28 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッド 迅速に発光する安定なアクリジニウムエステル
WO2009067417A1 (en) * 2007-11-20 2009-05-28 Siemens Heathcare Diagnostics Inc. Facile n-alkylation of acridine compounds in ionic liquids
CN114245830A (zh) * 2019-08-07 2022-03-25 深圳华大基因科技有限公司 含吖啶酯的化合物及将其用于基于化学发光的单色测序的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110932A (en) * 1986-10-06 1992-05-05 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
US4918192A (en) * 1986-10-06 1990-04-17 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
US4745181A (en) * 1986-10-06 1988-05-17 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
US5151518A (en) * 1987-10-02 1992-09-29 Abbott Laboratories N-arylation of isatins
NL8703075A (nl) * 1987-12-18 1989-07-17 Nederlanden Staat Acridiniumverbindingen als chemiluminescentie-merkstof.
US5283334A (en) * 1987-12-31 1994-02-01 London Diagnostics, Inc. Side-chain functional chemiluminescent labels and their conjugates, and assays therefrom
NZ227506A (en) * 1987-12-31 1992-06-25 London Diagnostics Inc Specific binding assays using chemiluminescent compounds
US5321136A (en) * 1987-12-31 1994-06-14 London Diagnostics, Inc. Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom
US4950613A (en) * 1988-02-26 1990-08-21 Gen-Probe Incorporated Proteted chemiluminescent labels
US5227489A (en) * 1988-08-01 1993-07-13 Ciba Corning Diagnostics Corp. Stable hydrophilic acridinium esters suitable for liposome encapsulation
US5241070A (en) * 1988-09-26 1993-08-31 Ciba Corning Diagnostics Corp. Nucleophilic polysubstituted aryl acridinium esters and uses thereof

Also Published As

Publication number Publication date
EP0609885A1 (de) 1994-08-10
DE69432497T2 (de) 2003-10-30
JPH06228102A (ja) 1994-08-16
JP3584379B2 (ja) 2004-11-04
US5594112A (en) 1997-01-14
ES2196012T3 (es) 2003-12-16
CA2114754A1 (en) 1994-08-05
DE69432497D1 (de) 2003-05-22
US5438139A (en) 1995-08-01
EP0609885B1 (de) 2003-04-16

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