DE69432497D1 - Akridinium Derivate und deren Konjugate - Google Patents

Akridinium Derivate und deren Konjugate

Info

Publication number
DE69432497D1
DE69432497D1 DE69432497T DE69432497T DE69432497D1 DE 69432497 D1 DE69432497 D1 DE 69432497D1 DE 69432497 T DE69432497 T DE 69432497T DE 69432497 T DE69432497 T DE 69432497T DE 69432497 D1 DE69432497 D1 DE 69432497D1
Authority
DE
Germany
Prior art keywords
group
specific binding
acridinium compounds
activity
conjugates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69432497T
Other languages
English (en)
Other versions
DE69432497T2 (de
Inventor
Naofumi Sato
Hiroshi Mochizuki
Toshinori Kanamori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mochida Pharmaceutical Co Ltd
Original Assignee
Mochida Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharmaceutical Co Ltd filed Critical Mochida Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69432497D1 publication Critical patent/DE69432497D1/de
Publication of DE69432497T2 publication Critical patent/DE69432497T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
DE69432497T 1993-02-04 1994-02-03 Akridinium Derivate und deren Konjugate Expired - Fee Related DE69432497T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP01746593A JP3584379B2 (ja) 1993-02-04 1993-02-04 アクリジニウム化合物およびアクリジニウム化合物複合体

Publications (2)

Publication Number Publication Date
DE69432497D1 true DE69432497D1 (de) 2003-05-22
DE69432497T2 DE69432497T2 (de) 2003-10-30

Family

ID=11944776

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69432497T Expired - Fee Related DE69432497T2 (de) 1993-02-04 1994-02-03 Akridinium Derivate und deren Konjugate

Country Status (7)

Country Link
US (2) US5438139A (de)
EP (1) EP0609885B1 (de)
JP (1) JP3584379B2 (de)
AT (1) ATE237592T1 (de)
CA (1) CA2114754A1 (de)
DE (1) DE69432497T2 (de)
ES (1) ES2196012T3 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7122671B1 (en) * 1979-07-19 2006-10-17 University College Cardiff Consultants Limited Luminescent labelling materials and procedures
US6414152B1 (en) * 1981-12-11 2002-07-02 University Of Wales College Of Medicine Of Heath Park Luminescent labelling material and procedures
EP0273115B1 (de) * 1986-10-22 1994-09-07 Abbott Laboratories Chemilumineszierende Acridinium- und Phenantridiniumsalze
US5656426A (en) * 1988-08-01 1997-08-12 Chiron Diagnostics Corporation Functionaized hydrophilic acridinium esters
US5593845A (en) * 1993-05-17 1997-01-14 Lumigen, Inc. Aryl N-alkylacridancarboxylate derivatives useful for chemiluminescent detection
GB2282222A (en) * 1993-09-09 1995-03-29 Univ Nottingham Detecting genetic material using labelled DNA
GB2289334B (en) * 1994-05-10 1998-08-26 Molecular Light Technology Lim Enzyme linked chemiluminescent assay
US5731148A (en) * 1995-06-07 1998-03-24 Gen-Probe Incorporated Adduct protection assay
EP0761652A1 (de) * 1995-08-01 1997-03-12 Mochida Pharmaceutical Co., Ltd. Acridiniumverbindung mit mehreren lumineszierenden Gruppen und Bindungsgruppen und Konjugate derselben
US6165800A (en) * 1997-05-30 2000-12-26 Bayer Corporation Chemiluminescent energy transfer conjugates and their uses as labels in binding assays
EP1019379B1 (de) * 1997-08-21 2005-10-19 Maine Medical Center Auf peroxiden basierender chemilumineszenztest und chemilumineszente verbindungen die in diesem benutzt werden
ATE423101T1 (de) 1998-08-11 2009-03-15 Siemens Healthcare Diagnostics Im nahen infrarot chemilumineszente akridinium derivate und ihre verwendung
US6673560B1 (en) 1998-11-25 2004-01-06 Bayer Corporation Measurement of hydride using chemiluminescent acridinium compounds and applications thereof
US6723851B2 (en) * 2001-10-31 2004-04-20 Quest Diagnostics Investment Incorporated Chemiluminescent compounds and use thereof
GB0320236D0 (en) * 2003-08-29 2003-10-01 Molecular Light Tech Res Ltd Chemiluminescent compounds
ES2392900T3 (es) * 2006-10-13 2012-12-14 Siemens Healthcare Diagnostics Inc. Ésteres de acridinio estables con emisión de luz rápida
EP2215063B1 (de) * 2007-11-20 2013-10-30 Siemens Healthcare Diagnostics Inc. Einfache n-alkylierung von acridinverbindungen in ionischen flüssigkeiten
CN114245830A (zh) * 2019-08-07 2022-03-25 深圳华大基因科技有限公司 含吖啶酯的化合物及将其用于基于化学发光的单色测序的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110932A (en) * 1986-10-06 1992-05-05 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
US4918192A (en) * 1986-10-06 1990-04-17 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
US4745181A (en) * 1986-10-06 1988-05-17 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
US5151518A (en) * 1987-10-02 1992-09-29 Abbott Laboratories N-arylation of isatins
NL8703075A (nl) * 1987-12-18 1989-07-17 Nederlanden Staat Acridiniumverbindingen als chemiluminescentie-merkstof.
US5284951A (en) * 1987-12-31 1994-02-08 London Diagnostics, Inc. Hydrolytically stable chemiluminescent labels and their conjugates, and assays therefrom
US5321136A (en) * 1987-12-31 1994-06-14 London Diagnostics, Inc. Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom
NZ227506A (en) * 1987-12-31 1992-06-25 London Diagnostics Inc Specific binding assays using chemiluminescent compounds
US4950613A (en) * 1988-02-26 1990-08-21 Gen-Probe Incorporated Proteted chemiluminescent labels
US5227489A (en) * 1988-08-01 1993-07-13 Ciba Corning Diagnostics Corp. Stable hydrophilic acridinium esters suitable for liposome encapsulation
US5241070A (en) * 1988-09-26 1993-08-31 Ciba Corning Diagnostics Corp. Nucleophilic polysubstituted aryl acridinium esters and uses thereof

Also Published As

Publication number Publication date
US5438139A (en) 1995-08-01
ES2196012T3 (es) 2003-12-16
ATE237592T1 (de) 2003-05-15
EP0609885A1 (de) 1994-08-10
EP0609885B1 (de) 2003-04-16
US5594112A (en) 1997-01-14
DE69432497T2 (de) 2003-10-30
JPH06228102A (ja) 1994-08-16
JP3584379B2 (ja) 2004-11-04
CA2114754A1 (en) 1994-08-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee