ATE70834T1 - Sulfamoyl-2-benzofurancarbonsaeure-derivate, ihre herstellung und ihre verwendung. - Google Patents
Sulfamoyl-2-benzofurancarbonsaeure-derivate, ihre herstellung und ihre verwendung.Info
- Publication number
- ATE70834T1 ATE70834T1 AT88309563T AT88309563T ATE70834T1 AT E70834 T1 ATE70834 T1 AT E70834T1 AT 88309563 T AT88309563 T AT 88309563T AT 88309563 T AT88309563 T AT 88309563T AT E70834 T1 ATE70834 T1 AT E70834T1
- Authority
- AT
- Austria
- Prior art keywords
- lower alkyl
- sulfamoyl
- acid derivatives
- hydrogen
- benzofurancarbonic
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- BRZBRJKXYHRDEH-UHFFFAOYSA-N 3-sulfamoyl-1-benzofuran-2-carboxylic acid Chemical class C1=CC=C2C(S(=O)(=O)N)=C(C(O)=O)OC2=C1 BRZBRJKXYHRDEH-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229940124567 diuretic antihypertensive agent Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000002171 loop diuretic Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cardiology (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62256890A JPH01100164A (ja) | 1987-10-12 | 1987-10-12 | スルファモイル−2−ベンゾフランカルボン酸誘導体 |
EP88309563A EP0312338B1 (de) | 1987-10-12 | 1988-10-12 | Sulfamoyl-2-benzofurancarbonsäure-Derivate, ihre Herstellung und ihre Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE70834T1 true ATE70834T1 (de) | 1992-01-15 |
Family
ID=17298833
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT88309563T ATE70834T1 (de) | 1987-10-12 | 1988-10-12 | Sulfamoyl-2-benzofurancarbonsaeure-derivate, ihre herstellung und ihre verwendung. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4918206A (de) |
EP (1) | EP0312338B1 (de) |
JP (1) | JPH01100164A (de) |
KR (1) | KR960011383B1 (de) |
AT (1) | ATE70834T1 (de) |
CA (1) | CA1333603C (de) |
DE (1) | DE3867202D1 (de) |
ES (1) | ES2039282T3 (de) |
GR (1) | GR3003762T3 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5387681A (en) * | 1992-08-19 | 1995-02-07 | Eli Lilly And Company | Synthesis of bicyclic aromatic sulfonic acids sulfonyl chlorides and sulfonamides |
JP6903576B2 (ja) * | 2014-12-10 | 2021-07-14 | トリシダ・インコーポレイテッドTricida, Inc. | 経口投与用プロトン結合ポリマー |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4085117A (en) * | 1976-10-18 | 1978-04-18 | Merck & Co., Inc. | 6,7-Disubstituted-5-(acyl)benzofuran-2-carboxylic acids |
US4663347A (en) * | 1983-10-31 | 1987-05-05 | Merck Frosst Canada, Inc. | Benzofuran 2-carboxylic acid esters useful as inhibitors of leukotriene biosynthesis |
JPS6163671A (ja) * | 1984-09-05 | 1986-04-01 | Shionogi & Co Ltd | 2,3−ジヒドロベンゾフラン−5−スルホンアミド誘導体および降圧利尿剤 |
CA1260947A (en) * | 1984-12-29 | 1989-09-26 | Yoshitaka Ohishi | Benzofuran derivative, process for preparing the same and pharmaceutical composition containing the same |
JP3095505B2 (ja) * | 1992-01-31 | 2000-10-03 | 沖電気工業株式会社 | 画像形成装置 |
-
1987
- 1987-10-12 JP JP62256890A patent/JPH01100164A/ja active Granted
-
1988
- 1988-09-16 US US07/245,294 patent/US4918206A/en not_active Expired - Fee Related
- 1988-09-16 CA CA000577580A patent/CA1333603C/en not_active Expired - Fee Related
- 1988-10-12 ES ES88309563T patent/ES2039282T3/es not_active Expired - Lifetime
- 1988-10-12 KR KR1019880013319A patent/KR960011383B1/ko active IP Right Grant
- 1988-10-12 DE DE8888309563T patent/DE3867202D1/de not_active Expired - Fee Related
- 1988-10-12 AT AT88309563T patent/ATE70834T1/de not_active IP Right Cessation
- 1988-10-12 EP EP88309563A patent/EP0312338B1/de not_active Expired - Lifetime
-
1992
- 1992-02-11 GR GR920400184T patent/GR3003762T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0312338A1 (de) | 1989-04-19 |
GR3003762T3 (de) | 1993-03-16 |
ES2039282T3 (es) | 1996-07-16 |
KR960011383B1 (ko) | 1996-08-22 |
US4918206A (en) | 1990-04-17 |
CA1333603C (en) | 1994-12-20 |
JPH01100164A (ja) | 1989-04-18 |
JPH0579069B2 (de) | 1993-11-01 |
KR890006609A (ko) | 1989-06-14 |
DE3867202D1 (de) | 1992-02-06 |
EP0312338B1 (de) | 1991-12-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |