KR890000097A - 항레트로비루스 작용을 갖는 당단백질 처리 억제제 - Google Patents

항레트로비루스 작용을 갖는 당단백질 처리 억제제 Download PDF

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Publication number
KR890000097A
KR890000097A KR1019880006795A KR880006795A KR890000097A KR 890000097 A KR890000097 A KR 890000097A KR 1019880006795 A KR1019880006795 A KR 1019880006795A KR 880006795 A KR880006795 A KR 880006795A KR 890000097 A KR890000097 A KR 890000097A
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KR
South Korea
Prior art keywords
glycoprotein
glycoprotein treatment
antiretrovirus
treatment inhibitor
inhibitor
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Application number
KR1019880006795A
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English (en)
Inventor
피.순카라 사이
엘.보울린 테리
에스.리우 폴
Original Assignee
게리 디.스트리트
머렐 다우 파마슈티칼스인크
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Application filed by 게리 디.스트리트, 머렐 다우 파마슈티칼스인크 filed Critical 게리 디.스트리트
Publication of KR890000097A publication Critical patent/KR890000097A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

내용 없음

Description

항레트로비루스 작용을 갖는 당단백질 처리 억제제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (8)

  1. 카스타노스페르민, 스와인소닌, 데옥시노지리마이신, 데옥시만노지리마이신, 브로모콘두리톨 및 투니카마이신 중에서 선택된 당단백질 처리 억제제의 항레트로비루스 유효량을 환자에게 투여하는 것으로 되는 치료를 필요로 하는 환자의 레트로비루스 감염 치료 방법.
  2. 카스타노스페르민, 스와인소닌, 데옥시노지리마이신, 데옥시만노지리마이신, 브로모콘두리톨 및 투니카마이신 중에서 선택된 당단백질 처리 억제제의 항레트로비루스 유효량을 환자에게 투여하는 것으로 되는 치료를 필요로 하는 환자의 HIV 감염 치료 방법.
  3. 제1항 또는 2항중 어느 하나의 항에 있어서, 당단백질 처리 억제제가 카스타노스페르민인 방법.
  4. 제1항 또는 제2항중 어느 하나의 항에 있어서, 당단백질 처리 억제제가 스와인소닌인 방법.
  5. 제1항 또는 제2항중 어느 하나의 항에 있어서, 당단백질 처리 억제제가 데옥시노지리마이신인 방법.
  6. 제1항 또는 2항중 어느 하나의 항에 있어서, 당단백질 처리 억제제가 데옥시만노지리마이신인 방법.
  7. 제1항 또는 2항중 어느 하나의 항에 있어서, 당단백질 처리 억제제가 브로모콘두리톨인 방법.
  8. 제1항 또는 2항중 어느 하나의 항에 있어서, 당단백질 처리 억제제가 투니카마이신인 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880006795A 1987-06-08 1988-06-07 항레트로비루스 작용을 갖는 당단백질 처리 억제제 KR890000097A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5896287A 1987-06-08 1987-06-08
US058,962 1987-06-08

Publications (1)

Publication Number Publication Date
KR890000097A true KR890000097A (ko) 1989-03-11

Family

ID=22019972

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880006795A KR890000097A (ko) 1987-06-08 1988-06-07 항레트로비루스 작용을 갖는 당단백질 처리 억제제

Country Status (7)

Country Link
EP (1) EP0295538A3 (ko)
JP (1) JP2720169B2 (ko)
KR (1) KR890000097A (ko)
AU (1) AU608853B2 (ko)
DK (1) DK308488A (ko)
PH (1) PH25896A (ko)
ZA (1) ZA883925B (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0252962B1 (en) * 1985-12-23 1995-08-23 Fred Hutchinson Cancer Research Center Regulating retroviral replication, infection, and pathogenesis
US5004746A (en) * 1987-09-29 1991-04-02 Merrell Dow Pharmaceuticals Inc. Anti-retroviral castanospermine esters
US5192772A (en) * 1987-12-09 1993-03-09 Nippon Shinyaku Co. Ltd. Therapeutic agents
GB8827701D0 (en) * 1987-12-09 1988-12-29 Nippon Shinyaku Co Ltd Thrombolytic &c compositions
FR2632526B1 (fr) * 1988-06-10 1994-05-13 Pasteur Institut Composition pharmaceutique active sur les residus glucose de la glycoproteine gp 150
EP0430983B1 (en) * 1988-08-10 1994-04-20 The Australian National University Use of castanospermine as an anti-inflammatory and immunosuppressant agent
AU618838B2 (en) * 1988-08-10 1992-01-09 Praxis Pharmaceuticals, Inc. Use of castanospermine as an anti-inflammatory and immunosuppressant agent
US5650413A (en) * 1995-06-07 1997-07-22 Glycodesign Inc. Derivatives of swainsonine, processes for their preparation and their use as therapeutic agents
US5908867A (en) * 1996-07-18 1999-06-01 Henry; James P. Reduction of hair growth
CA2267412A1 (en) * 1996-10-01 1998-04-09 Glycodesign Inc. Novel 3, 5, and/or 6 substituted analogues of swainsonine, processes for their preparation and their use as therapeutic agents
US6395745B1 (en) 1997-04-15 2002-05-28 Glycodesign, Inc. Alkaloid halide salts of swainsonine and methods of use
JP2001521036A (ja) * 1997-10-24 2001-11-06 グリコデザイン インコーポレイテッド スワインソニン塩の合成
AU761748B2 (en) * 1997-12-11 2003-06-12 Chancellor, Masters And Scholars Of The University Of Oxford, The Inhibition of membrane-associated viral replication
US6670374B1 (en) * 2002-06-11 2003-12-30 The United States Of America As Represented By The Secretary Of Agriculture Swainsonine compounds as inhibitors of toxin receptor expression
GB0501352D0 (en) * 2005-01-21 2005-03-02 Slingsby Jason H Use of glycosylation modulators in combination with membrane fusion inhibitors for treatment of infections caused by viruses bearing glycosylated envelope
US20060194835A1 (en) * 2005-02-09 2006-08-31 Migenix Inc. Compositions and methods for treating or preventing flaviviridae infections

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0252962B1 (en) * 1985-12-23 1995-08-23 Fred Hutchinson Cancer Research Center Regulating retroviral replication, infection, and pathogenesis
EP0282618A1 (en) * 1987-03-18 1988-09-21 Vereniging Het Nederlands Kanker Instituut 1-Deoxynojirimycin as an anti-HIV therapeutic
IL88740A (en) * 1987-12-21 1993-01-31 Monsanto Co Pharmaceutical compositions containing n-n-butyl deoxynojirimycin for treating aids

Also Published As

Publication number Publication date
JPS63310819A (ja) 1988-12-19
AU608853B2 (en) 1991-04-18
PH25896A (en) 1991-12-19
AU1739788A (en) 1988-12-08
EP0295538A3 (en) 1991-04-03
DK308488A (da) 1988-12-09
ZA883925B (en) 1989-02-22
EP0295538A2 (en) 1988-12-21
JP2720169B2 (ja) 1998-02-25
DK308488D0 (da) 1988-06-07

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