ATE159427T1 - Anwendung des n-n-butyl-derivates von desoxynojirimycin zur herstellung eines arzneimittels zur inhibierung von hiv-virus - Google Patents

Anwendung des n-n-butyl-derivates von desoxynojirimycin zur herstellung eines arzneimittels zur inhibierung von hiv-virus

Info

Publication number
ATE159427T1
ATE159427T1 AT88870191T AT88870191T ATE159427T1 AT E159427 T1 ATE159427 T1 AT E159427T1 AT 88870191 T AT88870191 T AT 88870191T AT 88870191 T AT88870191 T AT 88870191T AT E159427 T1 ATE159427 T1 AT E159427T1
Authority
AT
Austria
Prior art keywords
desoxynojirimycin
medicine
production
hiv virus
inhibiting hiv
Prior art date
Application number
AT88870191T
Other languages
English (en)
Inventor
Raymond Allen Dwek
George William John Fleet
Thomas William Rademacher
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/248,461 external-priority patent/US4849430A/en
Application filed by Monsanto Co filed Critical Monsanto Co
Application granted granted Critical
Publication of ATE159427T1 publication Critical patent/ATE159427T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT88870191T 1987-12-21 1988-12-20 Anwendung des n-n-butyl-derivates von desoxynojirimycin zur herstellung eines arzneimittels zur inhibierung von hiv-virus ATE159427T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13622487A 1987-12-21 1987-12-21
US16606588A 1988-03-09 1988-03-09
US07/248,461 US4849430A (en) 1988-03-09 1988-09-23 Method of inhibiting virus

Publications (1)

Publication Number Publication Date
ATE159427T1 true ATE159427T1 (de) 1997-11-15

Family

ID=27384837

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88870191T ATE159427T1 (de) 1987-12-21 1988-12-20 Anwendung des n-n-butyl-derivates von desoxynojirimycin zur herstellung eines arzneimittels zur inhibierung von hiv-virus

Country Status (15)

Country Link
EP (1) EP0324328B1 (de)
JP (1) JPH01203326A (de)
KR (1) KR910010020B1 (de)
AT (1) ATE159427T1 (de)
AU (1) AU605661B2 (de)
CA (1) CA1316459C (de)
DE (1) DE3856052T2 (de)
DK (1) DK175094B1 (de)
ES (1) ES2108680T3 (de)
GR (1) GR3025518T3 (de)
IE (1) IE81173B1 (de)
IL (1) IL88740A (de)
NZ (1) NZ227411A (de)
OA (1) OA09027A (de)
PT (1) PT89266B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA883925B (en) * 1987-06-08 1989-02-22 Merrell Dow Pharma Inhibitors of glycoprotein processing having anti-retroviral activity
US5144037A (en) * 1988-11-03 1992-09-01 G. D. Searle & Co. 1,5-dideoxy-1,5-imino-d-glucitol derivatives
US20030100532A1 (en) 1997-02-14 2003-05-29 Gary S. Jacob Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections
DK1030839T3 (da) * 1997-11-10 2004-05-03 Searle & Co Anvendelse af alkylerede iminosukkere til behandling af multidrugresistens
US6809083B1 (en) 1998-02-12 2004-10-26 Richard A. Mueller Use of N-substituted-1, 5-dideoxy-1, 5-imino-D-glucitol compounds for treating hepatitis virus infections
US6689759B1 (en) 1998-02-12 2004-02-10 G. D. Searle & Co. Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy
AU3858600A (en) 1999-02-12 2001-02-19 G.D. Searle & Co. Glucamine compounds for treating hepatitis virus infections
ATE402701T1 (de) 1999-02-12 2008-08-15 United Therapeutics Corp N-(8,8,8-trifluorooctyl)-1,5-dideoxy-1,5-imino- - glucitol zur behandlung von hepatitis-virus- infektionen
EP2356990A3 (de) * 2006-08-02 2011-10-19 University of Oxford Liposomen-Behandlung von Virusinfektionen
CN115806913B (zh) * 2022-10-21 2023-09-08 福建省农业科学院植物保护研究所 野尻链霉菌（Streptomyces nojiriensis）菌株9-13及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065562A (en) * 1975-12-29 1977-12-27 Nippon Shinyaku Co., Ltd. Method and composition for reducing blood glucose levels
JPS5311800A (en) * 1976-07-20 1978-02-02 Asahi Chemical Ind Method of well preserving and transporting live fish and apparatus therefor
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
DE3737523A1 (de) * 1987-11-05 1989-05-18 Bayer Ag Verwendung von substituierten hydroxypiperidinen als antivirale mittel

Also Published As

Publication number Publication date
IL88740A (en) 1993-01-31
DE3856052T2 (de) 1998-02-19
DK707988D0 (da) 1988-12-20
PT89266A (pt) 1989-12-29
OA09027A (fr) 1991-03-31
JPH01203326A (ja) 1989-08-16
NZ227411A (en) 1997-03-24
AU605661B2 (en) 1991-01-17
ES2108680T3 (es) 1998-01-01
KR910010020B1 (ko) 1991-12-10
DK175094B1 (da) 2004-06-01
IL88740A0 (en) 1989-07-31
DE3856052D1 (de) 1997-11-27
IE883793L (en) 1989-06-21
DK707988A (da) 1989-06-22
EP0324328A3 (de) 1990-06-20
KR890009401A (ko) 1989-08-01
EP0324328A2 (de) 1989-07-19
IE81173B1 (en) 2000-05-31
EP0324328B1 (de) 1997-10-22
CA1316459C (en) 1993-04-20
GR3025518T3 (en) 1998-02-27
PT89266B (pt) 1993-11-30
AU2706788A (en) 1989-06-22
JPH0521891B2 (de) 1993-03-25

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee