KR890011589A - 벤즈아미드의 용도 - Google Patents

벤즈아미드의 용도 Download PDF

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Publication number
KR890011589A
KR890011589A KR1019890000867A KR890000867A KR890011589A KR 890011589 A KR890011589 A KR 890011589A KR 1019890000867 A KR1019890000867 A KR 1019890000867A KR 890000867 A KR890000867 A KR 890000867A KR 890011589 A KR890011589 A KR 890011589A
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KR
South Korea
Prior art keywords
intelligent
dementia
benzamide
disorder
morpholinoethyl
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KR1019890000867A
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English (en)
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KR960016203B1 (ko
Inventor
암라인 로만
아난트 라비
Original Assignee
쟝-자끄 오가이, 프리돌린 클라우스너
에프. 호프만-라 로슈 앤드 캄파니 아크티엔게젤샤프트
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Application filed by 쟝-자끄 오가이, 프리돌린 클라우스너, 에프. 호프만-라 로슈 앤드 캄파니 아크티엔게젤샤프트 filed Critical 쟝-자끄 오가이, 프리돌린 클라우스너
Publication of KR890011589A publication Critical patent/KR890011589A/ko
Application granted granted Critical
Publication of KR960016203B1 publication Critical patent/KR960016203B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음

Description

벤즈아미드의 용도
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (12)

  1. 지능 장해의 치료 또는 예방을 위한 P-클로로-N-(2-몰폴리노에틸)-벤즈아미드의 용도.
  2. 지능 장해의 치료 또는 예방용 약제를 제조하기 위한 P-클로로-N-(2-몰폴리노에틸)-벤즈아미드의 용도.
  3. 제1항 또는 제2항에 있어서, 지능 장해가 노령기에 유발되는 용도.
  4. 제3항에 있어서, 지능 장해가 기억력 감퇴인 용도.
  5. 제1항 또는 제2항에 있어서, 지능 장해가 퇴행성 치매인 용도.
  6. 제5항에 있어서, 지능 치매가 알자이머(A'lzheimer)형 치매 또는 다-경색 유도된 치매인 용도.
  7. 상기에 언급된 본 발명.
  8. 지능 장해의 치료 및 예방이 필요한 환자에게 유효량의 P-클로로-N-(2-몰폴리노에틸)-벤즈아미드를 투여시킴을 특징으로 하여, 지능 장해를 치료 또는 예방하는 방법.
  9. 제8항에 있어서, 노령기에 유발된 지능장해를 치료 또는 예방하는 방법.
  10. 제9항에 있어서, 기억력 감퇴를 치료 또는 예방하는 방법.
  11. 제8항에 있어서, 퇴행성 치매를 치료 또는 예방하는 방법.
  12. 제11항에 있어서, 알자이머형 치매 또는 다-경색 유발된 치매를 치료 또는 예방하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890000867A 1988-01-28 1989-01-27 벤즈아미드를 포함하는 약제학적 조성물 KR960016203B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH29888 1988-01-28
CH00298/88-2 1988-01-28
CH298/88 1988-01-28

Publications (2)

Publication Number Publication Date
KR890011589A true KR890011589A (ko) 1989-08-21
KR960016203B1 KR960016203B1 (ko) 1996-12-06

Family

ID=4183804

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890000867A KR960016203B1 (ko) 1988-01-28 1989-01-27 벤즈아미드를 포함하는 약제학적 조성물

Country Status (15)

Country Link
US (1) US4906626A (ko)
EP (1) EP0326023B1 (ko)
JP (1) JPH07116043B2 (ko)
KR (1) KR960016203B1 (ko)
AT (1) ATE113207T1 (ko)
AU (1) AU620584B2 (ko)
CA (1) CA1332151C (ko)
DE (1) DE58908544D1 (ko)
DK (1) DK171094B1 (ko)
ES (1) ES2063060T3 (ko)
HU (1) HU203042B (ko)
IE (1) IE65409B1 (ko)
IL (1) IL89031A (ko)
PH (1) PH26030A (ko)
ZA (1) ZA89523B (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0279990B1 (en) * 1986-12-17 1995-07-12 Glaxo Group Limited Use of heterocyclic derivatives in the treatment of cognitive disorders
FR2645742A1 (fr) * 1989-04-12 1990-10-19 Delagrange Laboratoires Application de derives de 2-methoxy 4-(4,5-dihydro 2-imidazolyl (ou 2-oxazolyl) amino) 5-chloro benzamide dans le traitement des troubles de la fonction cognitive
JP3172202B2 (ja) * 1990-11-29 2001-06-04 エフ．ホフマン−ラ ロシュ アーゲー 不安の障害の処置剤
US6951884B2 (en) * 2002-06-12 2005-10-04 Hoffmann-La Roche Inc. Fluorobenzamides and uses thereof
BRPI0415842A (pt) * 2003-10-23 2007-01-02 Hoffmann La Roche derivativos de benzapepina como inibidores de mao-b
EP1713486A4 (en) * 2003-12-02 2009-04-29 Sheldon Leslie James COMBINED THERAPY FOR THE TREATMENT OF DEMENTIA, DEPRESSION AND APATHY
EP2612854B1 (en) 2005-10-25 2015-04-29 Shionogi&Co., Ltd. Aminothiazolidine and aminotetrahydrothiazepine derivatives as BACE 1 inhibitors
TW200902526A (en) * 2007-04-24 2009-01-16 Shionogi & Amp Co Ltd Aminodihydrothiazin derivative substituted with a cyclic group
JP5383483B2 (ja) 2007-04-24 2014-01-08 塩野義製薬株式会社 アルツハイマー症治療用医薬組成物
NZ589590A (en) 2008-06-13 2012-05-25 Shionogi & Co Sulfur-containing heterocyclic derivative having beta-secretase-inhibiting activity
JPWO2010047372A1 (ja) * 2008-10-22 2012-03-22 塩野義製薬株式会社 Ｂａｃｅ１阻害活性を有する２−アミノピリミジン−４−オンおよび２−アミノピリジン誘導体
US8999980B2 (en) 2009-12-11 2015-04-07 Shionogi & Co., Ltd. Oxazine derivatives
US9018219B2 (en) 2010-10-29 2015-04-28 Shionogi & Co., Ltd. Fused aminodihydropyrimidine derivative
EP2634186A4 (en) 2010-10-29 2014-03-26 Shionogi & Co naphthyridine
WO2012147763A1 (ja) 2011-04-26 2012-11-01 塩野義製薬株式会社 オキサジン誘導体およびそれを含有するｂａｃｅ１阻害剤
JP2016501827A (ja) 2012-10-24 2016-01-21 塩野義製薬株式会社 Ｂａｃｅ１阻害作用を有するジヒドロオキサジンまたはオキサゼピン誘導体
US10599006B2 (en) 2016-04-12 2020-03-24 E-Vision Smart Optics, Inc. Electro-active lenses with raised resistive bridges
CN114815435A (zh) 2016-04-12 2022-07-29 E-视觉智能光学公司 具有凸起电阻性桥的电活性透镜

Also Published As

Publication number Publication date
IE890273L (en) 1989-07-28
ZA89523B (en) 1989-09-27
CA1332151C (en) 1994-09-27
DK36889D0 (da) 1989-01-27
PH26030A (en) 1992-01-29
HUT50042A (en) 1989-12-28
EP0326023A2 (de) 1989-08-02
IL89031A (en) 1995-07-31
ES2063060T3 (es) 1995-01-01
AU2883689A (en) 1989-08-03
US4906626A (en) 1990-03-06
AU620584B2 (en) 1992-02-20
IE65409B1 (en) 1995-10-18
JPH07116043B2 (ja) 1995-12-13
HU203042B (en) 1991-05-28
JPH01224318A (ja) 1989-09-07
DK171094B1 (da) 1996-06-03
IL89031A0 (en) 1989-08-15
EP0326023B1 (de) 1994-10-26
DE58908544D1 (de) 1994-12-01
ATE113207T1 (de) 1994-11-15
DK36889A (da) 1989-07-29
KR960016203B1 (ko) 1996-12-06
EP0326023A3 (en) 1990-09-05

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