KR880010737A - 반투성 신경유도 채널 - Google Patents
반투성 신경유도 채널 Download PDFInfo
- Publication number
- KR880010737A KR880010737A KR1019880003342A KR880003342A KR880010737A KR 880010737 A KR880010737 A KR 880010737A KR 1019880003342 A KR1019880003342 A KR 1019880003342A KR 880003342 A KR880003342 A KR 880003342A KR 880010737 A KR880010737 A KR 880010737A
- Authority
- KR
- South Korea
- Prior art keywords
- membrane
- semipermeable
- tubular
- nerve
- microns
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B17/1128—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis of nerves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/26—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00491—Surgical glue applicators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/30199—Three-dimensional shapes
- A61F2002/30224—Three-dimensional shapes cylindrical
- A61F2002/30235—Three-dimensional shapes cylindrical tubular, e.g. sleeves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/32—Materials or treatment for tissue regeneration for nerve reconstruction
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제 1 도는 반투성, 전투성 및 불투성 신경 유도물질의 재생능력(신경섬유화된 축색돌기의 수로 판정)을 비교한 그래프이다.
제 2 도는 반투성 및 불투성 신경 유도물질의 재생 능력(상이한 신경 케이블 성분의 상대적 횡단면적을 백분율로 표시)을 비교한 챠트이다.
Claims (10)
- 모세혈관이 안쪽으로 성장하도록 하는 다공성 외막 표면 및 막을 통해 손상된 신경의 재생이 가능하도록 하는 매끄로운 내막 표면을 지님을 특징으로 하는, 손상된 신경의 말단을 수용하기에 적합한 개방부를 지닌 관상 반투성 막을 함유하는, 손상된 신경을 재생시키는데 사용하는 의료장치.
- 제 1 항에 있어서, 막의 두께가 약 0.05 내지 약 1.0mm 범위내임을 특징으로 하는 장치.
- 제 1 항에 있어서, 장치의 관강(lumen)의 직경이 약 0.5mm 내지 약 2cm 범위내임에 특징으로 하는 장치.
- 제 1 항에 있어서, 막이 약 100,000달톤 이하의 분자량을 갖는 용질에 대해 투과성임을 특지응로 하는 장치.
- 제 1 항에 있어서, 막이 섬유아세포 및 그밖의 반흔-형성 결합 조직세포에 대해 불투성임을 특징으로 하는 장치.
- 제 1 항에 있어서, 외막표면이 크기가 약 1 내지 약 20마이크론 범위내인 포어(pore)를 지님을 특징으로 하는 장치.
- 제 1 항에 있어서, 내막표면이 크기가 약 20 내지 2000Å 범위내인 포어를 지님을 특징으로 하는 장치.
- 제 1 항에 있어서, 막이 외막 및 내막표면 사이에 위치하는 상호소통을 위한 방사상 공극의 망상구조를 포함함을 특징으로 하는 장치.
- 제 1 항에 있어서, 막이 외막 및 내막 표면 사이에 위치하는 세로 방향으로 배향된 트라베쿨라(trabeculae)의 명상구조를 포함함을 특징으로 하는 장치.
- 제 1 항에 있어서, 막이 아크릴 공중합체, 폴리비닐리덴 플루오라이드 및 폴리우레탄 이소시아네이트로 구성된 그룹 중에서 선택된 중합체 물질을 함유함을 특징으로 하는 장치.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US032489 | 1987-03-30 | ||
US32489 | 1987-03-30 | ||
US07/032,489 US4877029A (en) | 1987-03-30 | 1987-03-30 | Semipermeable nerve guidance channels |
Publications (2)
Publication Number | Publication Date |
---|---|
KR880010737A true KR880010737A (ko) | 1988-10-24 |
KR900000845B1 KR900000845B1 (ko) | 1990-02-17 |
Family
ID=21865200
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019880003342A KR900000845B1 (ko) | 1987-03-30 | 1988-03-28 | 반투성 신경 유도 채널 |
Country Status (15)
Country | Link |
---|---|
US (1) | US4877029A (ko) |
EP (1) | EP0286284B1 (ko) |
KR (1) | KR900000845B1 (ko) |
AT (1) | ATE69710T1 (ko) |
AU (1) | AU597811B2 (ko) |
BR (1) | BR8801435A (ko) |
CA (1) | CA1293596C (ko) |
DE (2) | DE3866399D1 (ko) |
DK (1) | DK172888A (ko) |
FI (1) | FI881473A (ko) |
IL (1) | IL85839A0 (ko) |
NO (1) | NO166832C (ko) |
NZ (1) | NZ224064A (ko) |
PT (1) | PT87106B (ko) |
ZA (1) | ZA882234B (ko) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
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WO1988006866A1 (en) * | 1987-03-13 | 1988-09-22 | Brown University Research Foundation, Inc. | Piezolectric nerve guidance channels |
US4955893A (en) * | 1988-05-09 | 1990-09-11 | Massachusetts Institute Of Technologh | Prosthesis for promotion of nerve regeneration |
US5011486A (en) * | 1988-11-18 | 1991-04-30 | Brown University Research Foundation | Composite nerve guidance channels |
US5026381A (en) * | 1989-04-20 | 1991-06-25 | Colla-Tec, Incorporated | Multi-layered, semi-permeable conduit for nerve regeneration comprised of type 1 collagen, its method of manufacture and a method of nerve regeneration using said conduit |
DE3941873A1 (de) * | 1989-12-19 | 1991-06-20 | Jakob Dr Bodziony | Hohlfaser mit der beschichtung von zellen, die mehrjaehrige implantation in arterien und venen ermoeglichen |
DE4002559A1 (de) * | 1990-01-18 | 1991-10-02 | Jakob Dr Bodziony | Ein extrakorporales oder ein implantierbares und biologisch aktive substanzen sezernierendes bio-artifizielles organ |
DE4001319A1 (de) * | 1990-01-18 | 1991-07-25 | Jakob Dr Bodziony | Ein implantierbares und biologisch aktive substanzen sezernierendes bioartifizielles organ |
DE4012079C2 (de) * | 1990-04-14 | 1997-11-06 | Jakob Dr Bodziony | Implantierbare Austausch- und Diffusionskammer |
US5344454A (en) * | 1991-07-24 | 1994-09-06 | Baxter International Inc. | Closed porous chambers for implanting tissue in a host |
US5545223A (en) * | 1990-10-31 | 1996-08-13 | Baxter International, Inc. | Ported tissue implant systems and methods of using same |
JP3508023B2 (ja) * | 1990-10-31 | 2004-03-22 | バクスター、インターナショナル、インコーポレイテッド | 密接血管化埋め込み材料 |
US5713888A (en) * | 1990-10-31 | 1998-02-03 | Baxter International, Inc. | Tissue implant systems |
US5314471A (en) * | 1991-07-24 | 1994-05-24 | Baxter International Inc. | Tissue inplant systems and methods for sustaining viable high cell densities within a host |
US6102921A (en) * | 1990-12-21 | 2000-08-15 | University Of New Mexico | Nerve anastomosis sling and method |
US6773458B1 (en) | 1991-07-24 | 2004-08-10 | Baxter International Inc. | Angiogenic tissue implant systems and methods |
US5453278A (en) * | 1991-07-24 | 1995-09-26 | Baxter International Inc. | Laminated barriers for tissue implants |
DE69215053T2 (de) * | 1991-09-26 | 1997-04-03 | United States Surgical Corp | Vorrichtung zum Reparieren von Nerven |
FI922517A (fi) * | 1992-05-29 | 1993-11-30 | Paeivi Liesi | Nervrepareringsmedel och dess anvaendning |
CA2148354A1 (en) * | 1993-09-24 | 1995-03-30 | Laura A. Martinson | Methods for enhancing vascularization of implant devices |
US6551618B2 (en) * | 1994-03-15 | 2003-04-22 | University Of Birmingham | Compositions and methods for delivery of agents for neuronal regeneration and survival |
US6156305A (en) * | 1994-07-08 | 2000-12-05 | Baxter International Inc. | Implanted tumor cells for the prevention and treatment of cancer |
US20050152950A1 (en) * | 1995-11-13 | 2005-07-14 | Saffran Bruce N. | Method and apparatus for macromolecular delivery using a coated membrane |
US6106558A (en) * | 1997-09-15 | 2000-08-22 | Applied Medical Research, Inc. | Neuro decompression device |
DE19750043A1 (de) * | 1997-11-12 | 1999-05-20 | Johann W Prof Dr Bartha | Neuartige Cuff-Elektrode und Verfahren zur Erzeugung dieser |
US6221109B1 (en) * | 1999-09-15 | 2001-04-24 | Ed. Geistlich Söhne AG fur Chemische Industrie | Method of protecting spinal area |
CZ301649B6 (cs) * | 2000-06-28 | 2010-05-12 | Ed. Geistlich Soehne Ag Fur Chemische Industrie Incorporated Under The Laws Of Switzerland | Trubice pro regeneraci nervu a zpusob jejich výroby |
US6716225B2 (en) * | 2001-08-02 | 2004-04-06 | Collagen Matrix, Inc. | Implant devices for nerve repair |
IL160188A0 (en) * | 2001-08-13 | 2004-07-25 | Univ Florida | Materials and methods to promote repair of nerve tissue |
TWI264301B (en) * | 2002-03-11 | 2006-10-21 | Ind Tech Res Inst | Multi-channel bioresorbable nerve regeneration conduit and preparation method for the same |
US7147647B2 (en) * | 2002-04-26 | 2006-12-12 | Medtronic, Inc. | Sintered titanium tube for the management of spinal cord injury |
WO2005046457A2 (en) * | 2003-11-05 | 2005-05-26 | Texas Scottish Rite Hospital For Children | A biomimetic biosynthetic nerve implant |
US20070100358A2 (en) * | 2002-08-01 | 2007-05-03 | Texas Scottish Rite Hospital For Children | A Biomimetic Synthetic Nerve Implant |
US9050393B2 (en) | 2005-02-08 | 2015-06-09 | Bruce N. Saffran | Medical devices and methods for modulation of physiology using device-based surface chemistry |
EP2131919A4 (en) * | 2007-04-02 | 2010-10-20 | Georgia Tech Res Inst | IMPLANT BRAKING DEVICE FOR COMMUNICATING WITH BIOLOGICAL TISSUE |
WO2016004283A1 (en) * | 2014-07-02 | 2016-01-07 | The Cleveland Clinic Foundation | Anastomosis devices and methods of using same |
US11179157B2 (en) | 2016-12-02 | 2021-11-23 | Integra Lifesciences Corporation | Devices and methods for nerve regeneration |
EP3638325A1 (en) * | 2017-06-13 | 2020-04-22 | Anatoli D. Dosta | Implant for injured nerve tissue prosthetics, method of surgical treatment for injured nerve tissue and use of porous polytetrafluorethylene |
RU2697775C1 (ru) * | 2018-03-23 | 2019-08-19 | Общество с ограниченной ответственностью "Линтекс" | Трубчатый имплантат в качестве направляющей оболочки нерва и способ регенерации нерва |
CA3159546A1 (en) * | 2019-11-01 | 2021-05-06 | Allegro 3D, Inc. | 3d-bioprinted scaffolds for tissue regeneration |
ES2961367T3 (es) | 2020-04-06 | 2024-03-11 | Integra Lifesciences Corp | Dispositivos y métodos para la regeneración de nervios |
CN111956869B (zh) * | 2020-08-07 | 2024-03-08 | 中南大学湘雅医院 | 一种缓慢促进神经生长的泵 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
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US3786817A (en) * | 1972-06-01 | 1974-01-22 | Palma J | Method and apparatus for aiding severed nerves to join |
US3833002A (en) * | 1973-09-10 | 1974-09-03 | J Palma | Apparatus for aiding severed nerves to join |
US3916905A (en) * | 1973-11-09 | 1975-11-04 | William E Kuhn | Method and means for the repair of severed peripheral nerves |
US4033938A (en) * | 1974-01-21 | 1977-07-05 | American Cyanamid Company | Polymers of unsymmetrically substituted 1,4-dioxane-2,5-diones |
US3960152A (en) * | 1974-01-21 | 1976-06-01 | American Cyanamid Company | Surgical sutures of unsymmetrically substituted 1,4-dioxane-2,5-diones |
US3988411A (en) * | 1974-02-11 | 1976-10-26 | American Cyanamid Company | Spinning and shaping poly-(N-acetyl-D-glucosamine) |
US4074713A (en) * | 1975-03-14 | 1978-02-21 | American Cyanamid Company | Poly(N-acetyl-D-glucosamine) products |
GB1537448A (en) * | 1976-08-20 | 1978-12-29 | Sumitomo Electric Industries | Vascular prostheses and process for production thereof |
JPS6037733B2 (ja) * | 1978-10-12 | 1985-08-28 | 住友電気工業株式会社 | 管状臓器補綴材及びその製造方法 |
DE2947743C2 (de) * | 1978-11-30 | 1983-12-08 | Sumitomo Electric Industries, Ltd., Osaka | Einheitliches, poröses röhrenförmiges Gebilde aus Polytetrafluoräthylen |
JPS57144756A (en) * | 1981-03-04 | 1982-09-07 | Koken Kk | Impermeable laminated film |
US4534349A (en) * | 1983-02-02 | 1985-08-13 | Minnesota Mining And Manufacturing Company | Absorbable sutureless nerve repair device |
US4481353A (en) * | 1983-10-07 | 1984-11-06 | The Children's Medical Center Corporation | Bioresorbable polyesters and polyester composites |
US4774967A (en) * | 1986-09-09 | 1988-10-04 | American Biointerface Corporation | Method and apparatus for mammalian nerve regeneration |
-
1987
- 1987-03-30 US US07/032,489 patent/US4877029A/en not_active Expired - Lifetime
-
1988
- 1988-03-23 IL IL85839A patent/IL85839A0/xx unknown
- 1988-03-25 DE DE8888302678T patent/DE3866399D1/de not_active Expired - Fee Related
- 1988-03-25 EP EP88302678A patent/EP0286284B1/en not_active Expired - Lifetime
- 1988-03-25 AT AT88302678T patent/ATE69710T1/de not_active IP Right Cessation
- 1988-03-28 KR KR1019880003342A patent/KR900000845B1/ko not_active IP Right Cessation
- 1988-03-28 PT PT87106A patent/PT87106B/pt not_active IP Right Cessation
- 1988-03-28 CA CA000562663A patent/CA1293596C/en not_active Expired - Lifetime
- 1988-03-29 BR BR8801435A patent/BR8801435A/pt unknown
- 1988-03-29 NO NO881382A patent/NO166832C/no unknown
- 1988-03-29 ZA ZA882234A patent/ZA882234B/xx unknown
- 1988-03-29 NZ NZ224064A patent/NZ224064A/xx unknown
- 1988-03-29 AU AU13829/88A patent/AU597811B2/en not_active Ceased
- 1988-03-29 DK DK172888A patent/DK172888A/da active IP Right Grant
- 1988-03-29 FI FI881473A patent/FI881473A/fi not_active IP Right Cessation
- 1988-03-30 DE DE8804334U patent/DE8804334U1/de not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FI881473A (fi) | 1988-10-01 |
KR900000845B1 (ko) | 1990-02-17 |
PT87106B (pt) | 1995-03-01 |
DK172888A (da) | 1988-09-30 |
EP0286284B1 (en) | 1991-11-27 |
CA1293596C (en) | 1991-12-31 |
AU597811B2 (en) | 1990-06-07 |
DK172888D0 (da) | 1988-03-29 |
IL85839A0 (en) | 1988-09-30 |
US4877029A (en) | 1989-10-31 |
JPS642637A (en) | 1989-01-06 |
DE8804334U1 (ko) | 1988-08-04 |
EP0286284A1 (en) | 1988-10-12 |
ATE69710T1 (de) | 1991-12-15 |
FI881473A0 (fi) | 1988-03-29 |
ZA882234B (en) | 1990-02-28 |
DE3866399D1 (de) | 1992-01-09 |
AU1382988A (en) | 1988-09-29 |
NZ224064A (en) | 1990-10-26 |
JPH0478301B2 (ko) | 1992-12-10 |
NO881382L (no) | 1988-10-03 |
NO166832C (no) | 1991-09-11 |
PT87106A (pt) | 1989-03-30 |
BR8801435A (pt) | 1988-11-01 |
NO166832B (no) | 1991-06-03 |
NO881382D0 (no) | 1988-03-29 |
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