KR880009649A - 과유지질혈증 및 아테롬성 동맥경화증의 방지 및 치료에서의 피리독신 유도체의 사용 - Google Patents
과유지질혈증 및 아테롬성 동맥경화증의 방지 및 치료에서의 피리독신 유도체의 사용 Download PDFInfo
- Publication number
- KR880009649A KR880009649A KR1019880001692A KR880001692A KR880009649A KR 880009649 A KR880009649 A KR 880009649A KR 1019880001692 A KR1019880001692 A KR 1019880001692A KR 880001692 A KR880001692 A KR 880001692A KR 880009649 A KR880009649 A KR 880009649A
- Authority
- KR
- South Korea
- Prior art keywords
- pyridoxine
- atherosclerosis
- treatment
- derivatives
- hyperlipidemia
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
Abstract
내용 없음.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (9)
- DE 24 61 742 C2에 따른 피리독신-5-'-인산에스테르글루타민산염 및 아스파라긴산염을 제외한 피리독신 유도체와 이들의 염의 과유지질혈증 및 아테롬성 동맥경화증의 예방 및 치료용 용도.
- 제1항에 있어서, 피리독살 및/또는 피리독살인산염 및/또는 피리독사민 및/또는 피리독사민인산염을 사용하는 것을 특징으로 하는 피리독신 유도체의 용도.
- 제1항에 있어서, 생리학적으로 흠잡을데 없는 제약학적 부형제와 보조제를 피리독신 유도체 또는 여러 유도체에 첨가하는 것을 특징으로 하는 피리독신 유도체의 용도.
- 제1항 내지 제3항에 있어서, 피리독신 유도체를 과유지질혈증과 아테롬성 동맥경화증 또는 부수되는 질병을 치료하는데 다른 활성성분과 똑같이 병용으로 사용하는 것을 특징으로 하는 피리독신 유도체의 용도.
- DE 24 61 742 C2 에 따른 피리독신-5'-인산에스테르 글루타민산염 및 아스파라긴산염을 제외한 피리독신 유도체 또는 이들의 염의 과유지질혈증 및 아테롬성 동맥경화증의 예방 및 치료용 용도.
- 피리독살 및/또는 피리독살 인산염 및/또는 피리독사민 및/또는 피리독사민인산염 또는 이들의 염의 과유지질혈증 및 아테롬성 동맥경화증의 예방 및 치료용 약제 제조용 용도.
- 제5항에 있어서, 피리독신 유도체를 제약학적으로 안전한 부형제 및/또는 보조제와 함께 고체형태 또는 수용액으로서 제조하는 것을 특징으로 하는 피리독신 유도체의 용도.
- 제1항에 있어서, 구강 사용을 위하여 생리학적으로 흠잡을데 없는 제약학적 담체 및 보조제로서 제조하는 것을 특징으로 하는 피리독신 유도체의 용도.
- 제1항 내지 제7항에 있어서, 위장 쥬스에 저항하는 형태로된 생리학적으로 흠잡을데 없는 제약학적 담체와 보조제로 제조하는 것을 특징으로 하는 피리독신 유도체의 용도.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEP3705549.6 | 1987-02-18 | ||
DE19873705549 DE3705549A1 (de) | 1987-02-18 | 1987-02-18 | Verwendung von pyridoxin-derivaten bei der prophylaxe und therapie von hyperlipidaemien und atherosklerose |
Publications (2)
Publication Number | Publication Date |
---|---|
KR880009649A true KR880009649A (ko) | 1988-10-04 |
KR950009094B1 KR950009094B1 (ko) | 1995-08-14 |
Family
ID=6321453
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019880001692A KR950009094B1 (ko) | 1987-02-18 | 1988-02-17 | 과유지질혈증 및 아테롬성 동맥경화증의 방지 및 치료용 피리독신 유도체를 함유한 제약학적 조성물 |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0282696B1 (ko) |
JP (2) | JPH0710777B2 (ko) |
KR (1) | KR950009094B1 (ko) |
AT (1) | ATE82125T1 (ko) |
CA (1) | CA1340246C (ko) |
DE (2) | DE3705549A1 (ko) |
DK (1) | DK55888A (ko) |
EG (1) | EG18335A (ko) |
ES (1) | ES2052609T3 (ko) |
GR (1) | GR3006693T3 (ko) |
HU (1) | HUT47850A (ko) |
ZA (1) | ZA88577B (ko) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6716858B1 (en) | 1995-08-28 | 2004-04-06 | Kansas University Medical Center | Methods for inhibiting diabetic complications |
US6740668B1 (en) | 1995-08-28 | 2004-05-25 | Kansas University Medical Center | Methods for inhibiting diabetic complications |
US6228858B1 (en) | 1995-09-12 | 2001-05-08 | University Of Kansas Medical Center | Advanced glycation end-product intermediaries and post-amadori inhibition |
US6750209B1 (en) | 1995-09-12 | 2004-06-15 | Kansas University Medical Center | Advanced glycation end-product intermediaries and post-amadori inhibition |
US5744451A (en) | 1995-09-12 | 1998-04-28 | Warner-Lambert Company | N-substituted glutamic acid derivatives with interleukin-1 β converting enzyme inhibitory activity |
US6730686B1 (en) | 1995-09-12 | 2004-05-04 | Kansas University Medical Center | Methods for inhibiting oxidative modification of proteins |
US7030146B2 (en) | 1996-09-10 | 2006-04-18 | University Of South Carolina | Methods for treating diabetic neuropathy |
US6043259A (en) * | 1998-07-09 | 2000-03-28 | Medicure Inc. | Treatment of cardiovascular and related pathologies |
AU1444600A (en) * | 1998-10-09 | 2000-05-01 | Kansas University Medical Center | Methods for inhibiting oxidative modification of proteins |
AU763464B2 (en) | 1999-03-08 | 2003-07-24 | Medicure Inc. | Pyridoxal analogues for vitamin B-6 disorders |
CA2376029A1 (en) | 1999-07-13 | 2001-01-18 | Medicure Inc. | Use of pyridoxin derivatives for the treatment of diabetes and related complications |
WO2001013900A2 (en) | 1999-08-24 | 2001-03-01 | Medicure International Inc. | Compositions for the treatment of cardiovascular diseases containing pyridoxal compounds and cardiovascular compounds |
AU2001237185B2 (en) | 2000-02-29 | 2006-02-02 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
CA2404329A1 (en) | 2000-03-28 | 2001-10-04 | Medicure International Inc. | Treatment of cerebrovascular disease |
JP2004502757A (ja) | 2000-07-07 | 2004-01-29 | メディキュア インターナショナル インコーポレイテッド | ピリドキシンおよびピリドキサール類縁体:心血管系治療薬 |
US6897228B2 (en) | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
US6548519B1 (en) | 2001-07-06 | 2003-04-15 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: novel uses |
WO2004084895A2 (en) * | 2003-03-27 | 2004-10-07 | Medicure, Inc. | Modulation of cell death |
EP1817288A4 (en) | 2004-10-28 | 2009-08-26 | Medicure Int Inc | DUAL ANTIPLÄTTCHEN / ANTIKOAGULANS PYRIDOXINANALOGE |
CA2593793A1 (en) * | 2005-01-05 | 2006-07-13 | Medicure International Inc. | Compounds and methods for regulating triglyceride levels |
FR3038227B1 (fr) | 2015-06-30 | 2018-08-17 | Assistance Publique - Hopitaux De Paris | Formulation effervescente a base de pyridoxal-5-phosphate |
WO2020003363A1 (ja) * | 2018-06-25 | 2020-01-02 | 学校法人近畿大学 | ニコチン摂取の影響による血管の劣化を防止するための健康食品または医薬組成物 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3373E (fr) | 1904-02-26 | 1904-10-27 | Joseph Louis Felix Garrigou | Procédé de traitement des vidanges et déchets organiques, et appareil d'ensemble permettant sa mise en oeuvre |
FR6707M (ko) * | 1966-04-29 | 1969-02-17 | ||
GB1070120A (en) * | 1966-05-06 | 1967-05-24 | Tanabe Seiyaku Co | Pyridoxine derivative and the preparation thereof |
FR7238M (ko) * | 1968-03-27 | 1969-09-01 | ||
FR2035765A1 (en) | 1969-03-06 | 1970-12-24 | Inst Rech Scient | Medicaments contg pyridoxine heparinates or - other vitamin b6 heparinates |
JPS5347110B2 (ko) * | 1971-11-02 | 1978-12-19 | ||
FR2176509A2 (en) | 1972-03-21 | 1973-11-02 | Inst Rech Scient | Pyridoxine p-chlorophenoxyisobutyrate prodn - giving very pure product from corresp acid and pyridoxine |
JPS5018470A (ko) * | 1973-05-31 | 1975-02-26 | ||
FR2260330A1 (en) | 1974-02-07 | 1975-09-05 | Innothera Lab Sa | Pyridoxine N-oxy nicotinate - hypolipaemiant and hypocholesterolemiant of good therapeutic index |
CH607773A5 (en) | 1974-12-24 | 1978-10-31 | Steigerwald Arzneimittelwerk | Process for the preparation of novel pyridoxine derivatives |
DE2461742C2 (de) | 1974-12-28 | 1983-01-27 | Steigerwald Arzneimittelwerk Gmbh, 6100 Darmstadt | Pyridoxin-5'-phosphorsäureester-Derivate sowie deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
FR2349330A1 (fr) * | 1976-04-29 | 1977-11-25 | Savini Emile | Composition destinee au traitement des hyperlipidemies |
JPS5347110A (en) * | 1976-10-12 | 1978-04-27 | Osaka Bosui Kensetsusha Kk | Impermeable wall forming method |
-
1987
- 1987-02-18 DE DE19873705549 patent/DE3705549A1/de not_active Withdrawn
-
1988
- 1988-01-20 DE DE8888100747T patent/DE3875760D1/de not_active Expired - Fee Related
- 1988-01-20 EP EP88100747A patent/EP0282696B1/de not_active Expired - Lifetime
- 1988-01-20 AT AT88100747T patent/ATE82125T1/de not_active IP Right Cessation
- 1988-01-20 ES ES88100747T patent/ES2052609T3/es not_active Expired - Lifetime
- 1988-01-28 ZA ZA880577A patent/ZA88577B/xx unknown
- 1988-02-01 EG EG53/88A patent/EG18335A/xx active
- 1988-02-03 DK DK055888A patent/DK55888A/da not_active Application Discontinuation
- 1988-02-16 HU HU88723A patent/HUT47850A/hu unknown
- 1988-02-17 JP JP63032943A patent/JPH0710777B2/ja not_active Expired - Lifetime
- 1988-02-17 KR KR1019880001692A patent/KR950009094B1/ko not_active IP Right Cessation
- 1988-02-18 CA CA000559285A patent/CA1340246C/en not_active Expired - Fee Related
-
1992
- 1992-12-28 GR GR920403159T patent/GR3006693T3/el unknown
-
1994
- 1994-09-02 JP JP6209830A patent/JP2588686B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0282696A3 (en) | 1989-06-14 |
JP2588686B2 (ja) | 1997-03-05 |
KR950009094B1 (ko) | 1995-08-14 |
DK55888D0 (da) | 1988-02-03 |
GR3006693T3 (ko) | 1993-06-30 |
ES2052609T3 (es) | 1994-07-16 |
ZA88577B (en) | 1988-07-28 |
EP0282696A2 (de) | 1988-09-21 |
HUT47850A (en) | 1989-04-28 |
EG18335A (en) | 1992-09-30 |
JPS63203621A (ja) | 1988-08-23 |
DE3875760D1 (de) | 1992-12-17 |
JPH0710777B2 (ja) | 1995-02-08 |
JPH07238020A (ja) | 1995-09-12 |
DE3705549A1 (de) | 1988-09-01 |
EP0282696B1 (de) | 1992-11-11 |
DK55888A (da) | 1988-08-19 |
CA1340246C (en) | 1998-12-15 |
ATE82125T1 (de) | 1992-11-15 |
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