ES2052609T3 - Utilizacion de derivados de piridoxina en la profilaxis y terapia de hiperlipidemias y aterosclerosis. - Google Patents

Utilizacion de derivados de piridoxina en la profilaxis y terapia de hiperlipidemias y aterosclerosis.

Info

Publication number
ES2052609T3
ES2052609T3 ES88100747T ES88100747T ES2052609T3 ES 2052609 T3 ES2052609 T3 ES 2052609T3 ES 88100747 T ES88100747 T ES 88100747T ES 88100747 T ES88100747 T ES 88100747T ES 2052609 T3 ES2052609 T3 ES 2052609T3
Authority
ES
Spain
Prior art keywords
prophylaxis
atherosclerosis
derivatives
piridoxine
hyperlipidemia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88100747T
Other languages
English (en)
Inventor
Ulrich Speck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Steigerwald Arzneimittelwerk GmbH
Original Assignee
Steigerwald Arzneimittelwerk GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Steigerwald Arzneimittelwerk GmbH filed Critical Steigerwald Arzneimittelwerk GmbH
Application granted granted Critical
Publication of ES2052609T3 publication Critical patent/ES2052609T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)

Abstract

SE DESCRIBE LA APLICACION DEL DERIVADO DE PIRIDOXINA Y SUS SALES COMO PIRIDOXAL, FOSFATO DE PIRIDOXAL, PIRIDOXAMINA Y FOSFATO DE PIRIDOXAMINA EN LA PROFILAXIS Y TERAPIA DE LA OBESIDAD Y ARTEREOESCLEROSIS. LOS DERIVADOS SON GLUTIMINATO Y ASPARAGINATO DEL ESTER DEL ACIDO FOSFORICO - 5'' - PIRIDOXINA QUE SE DESCRIBEN EN LA PATENTE DE 2461742 C2. SE EMPLEAN SUBSTANCIAS QUIMICAS, ESTABLES NATURALES, TOLERANTES Y QUE TIENEN UNA GRAN EFECTIVIDAD PARA LA DISPOSICION DE LA TERAPIA A LARGO PLAZO. TIENE UNA FORMA PARA SU APLICACION BUCAL Y PRODUCE FORMAS RESISTENTES AL JUGO GASTRICO.
ES88100747T 1987-02-18 1988-01-20 Utilizacion de derivados de piridoxina en la profilaxis y terapia de hiperlipidemias y aterosclerosis. Expired - Lifetime ES2052609T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873705549 DE3705549A1 (de) 1987-02-18 1987-02-18 Verwendung von pyridoxin-derivaten bei der prophylaxe und therapie von hyperlipidaemien und atherosklerose

Publications (1)

Publication Number Publication Date
ES2052609T3 true ES2052609T3 (es) 1994-07-16

Family

ID=6321453

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88100747T Expired - Lifetime ES2052609T3 (es) 1987-02-18 1988-01-20 Utilizacion de derivados de piridoxina en la profilaxis y terapia de hiperlipidemias y aterosclerosis.

Country Status (12)

Country Link
EP (1) EP0282696B1 (es)
JP (2) JPH0710777B2 (es)
KR (1) KR950009094B1 (es)
AT (1) ATE82125T1 (es)
CA (1) CA1340246C (es)
DE (2) DE3705549A1 (es)
DK (1) DK55888A (es)
EG (1) EG18335A (es)
ES (1) ES2052609T3 (es)
GR (1) GR3006693T3 (es)
HU (1) HUT47850A (es)
ZA (1) ZA88577B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6716858B1 (en) 1995-08-28 2004-04-06 Kansas University Medical Center Methods for inhibiting diabetic complications
US6740668B1 (en) 1995-08-28 2004-05-25 Kansas University Medical Center Methods for inhibiting diabetic complications
US6228858B1 (en) 1995-09-12 2001-05-08 University Of Kansas Medical Center Advanced glycation end-product intermediaries and post-amadori inhibition
US6750209B1 (en) 1995-09-12 2004-06-15 Kansas University Medical Center Advanced glycation end-product intermediaries and post-amadori inhibition
US5744451A (en) 1995-09-12 1998-04-28 Warner-Lambert Company N-substituted glutamic acid derivatives with interleukin-1 β converting enzyme inhibitory activity
US6730686B1 (en) 1995-09-12 2004-05-04 Kansas University Medical Center Methods for inhibiting oxidative modification of proteins
US7030146B2 (en) 1996-09-10 2006-04-18 University Of South Carolina Methods for treating diabetic neuropathy
US6043259A (en) * 1998-07-09 2000-03-28 Medicure Inc. Treatment of cardiovascular and related pathologies
AU1444600A (en) * 1998-10-09 2000-05-01 Kansas University Medical Center Methods for inhibiting oxidative modification of proteins
AU763464B2 (en) 1999-03-08 2003-07-24 Medicure Inc. Pyridoxal analogues for vitamin B-6 disorders
CA2376029A1 (en) 1999-07-13 2001-01-18 Medicure Inc. Use of pyridoxin derivatives for the treatment of diabetes and related complications
WO2001013900A2 (en) 1999-08-24 2001-03-01 Medicure International Inc. Compositions for the treatment of cardiovascular diseases containing pyridoxal compounds and cardiovascular compounds
AU2001237185B2 (en) 2000-02-29 2006-02-02 Medicure International Inc. Cardioprotective phosphonates and malonates
CA2404329A1 (en) 2000-03-28 2001-10-04 Medicure International Inc. Treatment of cerebrovascular disease
JP2004502757A (ja) 2000-07-07 2004-01-29 メディキュア　インターナショナル　インコーポレイテッド ピリドキシンおよびピリドキサール類縁体：心血管系治療薬
US6897228B2 (en) 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses
WO2004084895A2 (en) * 2003-03-27 2004-10-07 Medicure, Inc. Modulation of cell death
EP1817288A4 (en) 2004-10-28 2009-08-26 Medicure Int Inc DUAL ANTIPLÄTTCHEN / ANTIKOAGULANS PYRIDOXINANALOGE
CA2593793A1 (en) * 2005-01-05 2006-07-13 Medicure International Inc. Compounds and methods for regulating triglyceride levels
FR3038227B1 (fr) 2015-06-30 2018-08-17 Assistance Publique - Hopitaux De Paris Formulation effervescente a base de pyridoxal-5-phosphate
WO2020003363A1 (ja) * 2018-06-25 2020-01-02 学校法人近畿大学 ニコチン摂取の影響による血管の劣化を防止するための健康食品または医薬組成物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3373E (fr) 1904-02-26 1904-10-27 Joseph Louis Felix Garrigou Procédé de traitement des vidanges et déchets organiques, et appareil d'ensemble permettant sa mise en oeuvre
FR6707M (es) * 1966-04-29 1969-02-17
GB1070120A (en) * 1966-05-06 1967-05-24 Tanabe Seiyaku Co Pyridoxine derivative and the preparation thereof
FR7238M (es) * 1968-03-27 1969-09-01
FR2035765A1 (en) 1969-03-06 1970-12-24 Inst Rech Scient Medicaments contg pyridoxine heparinates or - other vitamin b6 heparinates
JPS5347110B2 (es) * 1971-11-02 1978-12-19
FR2176509A2 (en) 1972-03-21 1973-11-02 Inst Rech Scient Pyridoxine p-chlorophenoxyisobutyrate prodn - giving very pure product from corresp acid and pyridoxine
JPS5018470A (es) * 1973-05-31 1975-02-26
FR2260330A1 (en) 1974-02-07 1975-09-05 Innothera Lab Sa Pyridoxine N-oxy nicotinate - hypolipaemiant and hypocholesterolemiant of good therapeutic index
CH607773A5 (en) 1974-12-24 1978-10-31 Steigerwald Arzneimittelwerk Process for the preparation of novel pyridoxine derivatives
DE2461742C2 (de) 1974-12-28 1983-01-27 Steigerwald Arzneimittelwerk Gmbh, 6100 Darmstadt Pyridoxin-5'-phosphorsäureester-Derivate sowie deren Herstellung und diese Verbindungen enthaltende Arzneimittel
FR2349330A1 (fr) * 1976-04-29 1977-11-25 Savini Emile Composition destinee au traitement des hyperlipidemies
JPS5347110A (en) * 1976-10-12 1978-04-27 Osaka Bosui Kensetsusha Kk Impermeable wall forming method

Also Published As

Publication number Publication date
EP0282696A3 (en) 1989-06-14
JP2588686B2 (ja) 1997-03-05
KR950009094B1 (ko) 1995-08-14
DK55888D0 (da) 1988-02-03
GR3006693T3 (es) 1993-06-30
ZA88577B (en) 1988-07-28
EP0282696A2 (de) 1988-09-21
HUT47850A (en) 1989-04-28
EG18335A (en) 1992-09-30
KR880009649A (ko) 1988-10-04
JPS63203621A (ja) 1988-08-23
DE3875760D1 (de) 1992-12-17
JPH0710777B2 (ja) 1995-02-08
JPH07238020A (ja) 1995-09-12
DE3705549A1 (de) 1988-09-01
EP0282696B1 (de) 1992-11-11
DK55888A (da) 1988-08-19
CA1340246C (en) 1998-12-15
ATE82125T1 (de) 1992-11-15

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