KR880006213A - 치환된 하이드록시프로필아민의 사카린염 - Google Patents

치환된 하이드록시프로필아민의 사카린염 Download PDF

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KR880006213A
KR880006213A KR870013009A KR870013009A KR880006213A KR 880006213 A KR880006213 A KR 880006213A KR 870013009 A KR870013009 A KR 870013009A KR 870013009 A KR870013009 A KR 870013009A KR 880006213 A KR880006213 A KR 880006213A
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methyl
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크래머 볼프강
바이스뮐러 요아힘
라이넥케 파울
핸슬러 게르트
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클라우스 댄너, 칼-루드비히 슈미트
바이엘 아크티엔게젤샤프트
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
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    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain

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Abstract

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Description

치환된 하이드록시프로필아민의 사카린염
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (10)

  1. 다음 일반식(I)의 치환된 하이드록시프로필아민의 사카린염.
    상기식에서, R1은 각각의 경우에 임의로 치환된 페닐, 페녹시, 페닐티오, 페닐알킬, 페녹시알킬 또는 페닐티오알킬을 나타내거나, 각각의 경우에 임의로 치환된 사이클로헥실, 사이클로헥실옥시, 사이클로헥실티오, 사이클로헥실알킬, 사이클로헥실옥시알킬 또는 사이클로헥실티오알킬을 나타내고, R2는 수소 또는 메틸을 나타내며, R3은 메틸 또는 에틸을 나타내고, R4및 R5는 각각 독립적으로 일킬 또는 알케닐을 나타내거나, R4및 R5는 이들이 결합된 질소원자와 함께 임의로 추가의 헤테로원자를 함유할 수 있는 임의로 치환된 포화 헤테로사이클릭 라디칼을 나타낸다.
  2. 제1항에 있어서, R1은 각각의 경우에 알킬부분에 1 또는 2개의 탄소원자를 가지며 각각의 경우에 동일하거나 상이한 치환체로 임의로 일-, 이-, 삼-, 사- 또는 오치환된 페닐, 페녹시, 페닐티오, 페닐알킬, 페녹시알킬 또는 페닐티오 알킬(여기서, 각각의 경우에 페닐상에 존재가능한 치환체는 할로겐, 각각의 경우에 1내지 5개의 탄소원자를 갖는 직쇄 또는 측쇄 알킬, 알콕시 및 알킬티오, 및 각각의 경우에 1내지 2개의 탄소원자와 1 내지 5개의 동일하거나 상이한 할로겐원자를 갖는 할로게노알킬, 할로게노알콕시 및 할로게노알킬티오이다)을 나타내거나, 각각에 경우에 알킬부분에 1 또는 2개의 탄소원자를 가지며 각각의 경우에 동일하거나 상이한 치환체로 임의로 일치환 또는 다치환된 사이클로헥실, 사이클로헥실옥시, 사이클로헥실티오, 사이클로헥실알킬, 사이클로헥실옥시알킬 또는 사이클로헥실티오알킬(여기서, 각각의 경우에 사이클로헥실상에 존재가능한 치환체는 각각의 경우에 1내지 5개의 탄소 원자를 갖는 직쇄 또는 측쇄 알킬 및 알콕시, 트리플루오로메틸 및 트리플루오로메톡시이다)을 나타내고, R2는 수소 또는 메틸을 나타내며, R3은 메틸 또는 에틸을 나타내고, R4및 R5는 각각 독립적으로 C1내지 C8의 직쇄 또는 측쇄 알킬 또는 C3내지 C8의 직쇄 또는 측쇄 알케닐을 나타내거나, R4및 R5는 이들이 결합하는 질소원자와 함께 1 또는 2개의 헤테로원자를 가지며 동일하거나 상이한 치환체(여기서, 존재가능한 치환체는 메틸, 에틸 및 하이드록시메틸이다)로 임의로 일-, 이-, 삼-, 사-, 오-, 육-, 칠-, 팔-, 구- 또는 십치환된 5- 내지 7-원 포화 헤테로사이클릭 라디칼을 나타내는 일반식(I)의 치환된 하이드록시프로필아민의 사카린염.
  3. 제1항에 있어서, R1은 각각의 경우에 동일하거나 상이한 치환체로 임의로 일-, 이- 또는 삼치환된 페닐, 페닐메틸, 페녹시메틸, 페닐티오메틸, 페녹시 또는 페닐티오(여기서, 페닐상에 존재가능한 치환체는 각각의 경우에 불소, 염소, 브롬, 메틸, 에틸, n-프로필, i-프로필, n-, i-, s- 또는 3급-부틸, n-펜틸, 2-메틸-2-부틸, 메톡시, 에톡시, n-또는 i-프로폭시, 3급-부톡시, 트리플루오로메틸, 트리플루오로메톡시 및 트리플루오로메틸티오이다)를 나타내거나, 각각의 경우에 동일하거나 상이한 치환체로 임의로 일-, 이- 또는 삼치환된 사이클로헥실, 사이클로헥실메틸, 사이클로헥실옥시메틸, 사이클로헥실티오메틸, 사이클로헥실옥시 또는 사이클로헥실티오(여기서, 사이클로헥실상에 존재가능한 치환체는 각각의 경우에 메틸, 에틸, n- 또는 i-프로필, n-, i-, s- 또는 3급-부틸, n-펜틸, 2-메틸-2-부틸, 메톡시, 에톡시, n-또는 i-프로폭시, 3급-부톡시, 트리플루오로메틸 및 트리플루오로메톡시이다)를 나타내고, R2는 수소 또는 메틸을 나타내며, R3은 메틸 또는 에틸을 나타내고, R4및 R5는 각각 독립적으로 메틸, 에틸, n- 또는 i-프로필, n-, i-, s- 또는 3급-부틸, n-펜틸, 알릴, 2-부테닐 또는 3-메틸-2-부테닐을 나타내거나, R4및 R5는 이들이 결합되어 있는 질소원자와 함께 각각의 경우에 메틸, 에틸 및 하이드록시메틸로 이루어진 그룹중에서 선택된 동일하거나 상이한 치환체로 임의로 일-, 이- 또는 삼치환된 1-필로리디닐, 1-피페리디닐, 1-피페라지닐, 4-모르폴리닐 또는 1-헥사하이드로아제피닐을 나타내는 일반식(I)의 치환된 하이드록시프로필아민의 사카린염.
  4. 제1항에 있어서, R1은 각각의 경우에 염소, 메틸, 3급-부틸 및 트리플루오로메톡시로 이루어진 그룹중에서 선택된 동일하거나 상이한 치환체로 임의로 일- 또는 이치환된 페닐, 페녹시, 페녹시메틸, 페닐티오메틸, 페닐티오, 사이클로헥실옥시, 사이클로헥실메틸 또는 사이클로헥실옥시메틸을 나타내고, R2는 수소 또는 메틸을 나타내며, R3은 메틸을 나타내고, R4및 R5는 이들이 결합된 질소원자와 함께 임의로 메틸에 의해 일-, 이- 또는 삼치환된 1- 피페리디닐, 4-모르폴리닐 또는 1- 헥사하이드로아제피닐을 나타내는 일반식(I)의 치환된 하이드록시프로필아민의 사카린염.
  5. 다음 일반식(Ⅱ)의 치환된 하이드록시프로필아민을, 경우에 따라, 희석제의 존재하에서 사카린과 반응시킴을 특징으로하여 다음 일반식(I)의 치환된 하이드록시프로필아민의 사카린염을 제조하는 방법.
    상기식에서, R1은 각각의 경우에 임의로 치환된 페닐, 페녹시, 페닐티오, 페닐아킬, 페녹시알킬 또는 페닐티오알킬을 나타내거나, 각각의 경우에 임의로 치환된 사이클로헥실, 사이클로헥실옥시, 사이클로헥실티오, 사이클로헥실알킬, 사이클로헥실옥시알킬 또는 사이클로헥실티오알킬을 나타내고, R2는 수소 또는 메틸을 나타내며, R3은 메틸 또는 에틸을 나타내고, R4및 R5는 각각 독립적으로 알킬 또는 알케닐을 나타내거나, R4및 R5는 이들이 결합된 질소원자와 함께 임의로 추가의 헤테로원자를 함유할 수 있는 임의로 치환된 포화 헤테로사이클릭 라디칼을 나타낸다.
  6. 적어도 하나의, 제1항 및 제5항에 따르는 일반식 (I)의 치환된 하이드록시프로필아민의 사카린염을 함유함을 특징으로하는 해충방제용 약제.
  7. 해충을 방제하기 위한 제1항 및 제5항에 따르는 일반식 (I)의 치환된 하이드록시프로필아민의 사카린염의 용도.
  8. 제1항 및 제5항에 따른 일반식(I)의 치환된 하이드록시프로필아민의 사카린염을 해충 또는 해충의환경에 작용시킴을 특징으로 하여 해충을 방제하는 제조하는 방법.
  9. 제1항 및 제5항에 따른 일반식(I)의 치환된 하이드록시프로필아민의 사카린염을 중량제 및/또는 계면활성제와 혼합함을 특징으로 하여 해충방제용 약제를 제조하는 방법.
  10. 제7항에 있어서, 진균을 방제하기 위한 일반식 (I)의 치환된 하이드록시프로필아민의 사카린염의 용도.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR870013009A 1986-11-22 1987-11-19 치환된 하이드록시프로필아민의 사카린염 KR880006213A (ko)

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DEP3639902.7 1986-11-22
DE19863639902 DE3639902A1 (de) 1986-11-22 1986-11-22 Saccharin-salze von substituierten hydroxypropylaminen

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GB9608771D0 (en) * 1996-04-27 1996-07-03 Agrevo Uk Ltd Pyrimethanil salts
US20050176790A1 (en) 2001-02-28 2005-08-11 Johannes Bartholomaus Pharmaceutical salts
DE10109763A1 (de) * 2001-02-28 2002-09-05 Gruenenthal Gmbh Pharmazeutische Salze
US7407518B2 (en) * 2002-04-23 2008-08-05 Diolen Industrial Fibers Gmbh Method for production of seat belt webbing
WO2009017813A1 (en) * 2007-08-02 2009-02-05 Teva Pharmaceutical Industries Ltd. O-desmethyl venlafaxine saccharinate
WO2011121452A2 (en) * 2010-03-29 2011-10-06 Pliva Hrvatska D.O.O. Crystal forms of o-desmethylvenlafaxine fumarate

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US2538645A (en) * 1948-10-18 1951-01-16 William F Hamilton Vasoconstrictor compounds of saccharin and pharmaceutical compositions produced therefrom
US3567723A (en) * 1966-05-21 1971-03-02 Meiji Seika Kaisha Tertiary aminoalkyl pentachlorophenyl ethers
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