KR880002708B1 - 4-아로일이미다졸리딘-2-온의 제조방법 - Google Patents

4-아로일이미다졸리딘-2-온의 제조방법 Download PDF

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Publication number
KR880002708B1
KR880002708B1 KR8204952A KR820004952A KR880002708B1 KR 880002708 B1 KR880002708 B1 KR 880002708B1 KR 8204952 A KR8204952 A KR 8204952A KR 820004952 A KR820004952 A KR 820004952A KR 880002708 B1 KR880002708 B1 KR 880002708B1
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KR
South Korea
Prior art keywords
hydrogen
substituted
oxygen atom
lower alkyl
compound
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Expired
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KR8204952A
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English (en)
Korean (ko)
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KR840002362A (ko
Inventor
안셀름 슈네틀러 리챠드
사이러스 데이지 리챠드
마틴 그리사 죠안
Original Assignee
메이나드 알.죤슨
메렐 다우 파마슈티칼스 인코포레이티드
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Publication of KR840002362A publication Critical patent/KR840002362A/ko
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Publication of KR880002708B1 publication Critical patent/KR880002708B1/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Supplying Of Containers To The Packaging Station (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
KR8204952A 1981-11-04 1982-11-03 4-아로일이미다졸리딘-2-온의 제조방법 Expired KR880002708B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/317,963 US4410540A (en) 1981-11-04 1981-11-04 Cardiotonic 4-aroylimidazolidin-2-ones
US317963 1981-11-04

Publications (2)

Publication Number Publication Date
KR840002362A KR840002362A (ko) 1984-06-25
KR880002708B1 true KR880002708B1 (ko) 1988-12-26

Family

ID=23236021

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8204952A Expired KR880002708B1 (ko) 1981-11-04 1982-11-03 4-아로일이미다졸리딘-2-온의 제조방법

Country Status (18)

Country Link
US (1) US4410540A (enExample)
EP (1) EP0079050B1 (enExample)
JP (1) JPS5885865A (enExample)
KR (1) KR880002708B1 (enExample)
AT (1) ATE26443T1 (enExample)
AU (1) AU552310B2 (enExample)
CA (1) CA1175829A (enExample)
DE (1) DE3275995D1 (enExample)
DK (1) DK488482A (enExample)
ES (1) ES517042A0 (enExample)
GB (1) GB2110669B (enExample)
GR (1) GR77375B (enExample)
IE (1) IE54265B1 (enExample)
IL (1) IL67133A0 (enExample)
NO (1) NO823648L (enExample)
NZ (1) NZ202350A (enExample)
PH (1) PH19029A (enExample)
ZA (1) ZA827974B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4709043A (en) * 1984-07-09 1987-11-24 Schering A.G. Process for the preparation of imidazolonecarbonylarylimidazoles
US4999365A (en) * 1987-03-20 1991-03-12 Merrell Dow Pharmaceuticals Inc. Method of reducing reperfusion injury with imidazol-2-thiones
US6159990A (en) * 1997-06-18 2000-12-12 Synaptic Pharmaceutical Corporation Oxazolidinones as α1A receptor antagonists
EP0988295A4 (en) * 1997-06-18 2003-08-13 Synaptic Pharma Corp PIPERIDINE SUBSTITUTED BY A HETEROCYCLIC REST AND THEIR USE
US7091238B1 (en) 1999-06-21 2006-08-15 University Of Maryland Thienylhydrazon with digitalis-like properties (positive inotropic effects)
EP1532140A1 (en) * 1999-06-21 2005-05-25 University of Maryland, Baltimore Thienylhydrazon with digitalis-like properties ( positive inotropic effects )
ES2157822B1 (es) * 1999-08-17 2002-04-16 Kylolab S L Procedimiento para la sintesis de 2-imidazolidinonas poli-sustituidas.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1184709A (fr) * 1957-09-21 1959-07-24 Cfmc Nouveaux dérivés imidazoliques, utilisables comme agents de protection contre les rayons ultra-violets et leurs procédés de fabrication
US3337580A (en) * 1964-12-31 1967-08-22 Robins Co Inc A H 1-hydrocarbon-3 aryl-4-substituted ethyl-2-imidazolidinones
NZ193935A (en) * 1979-06-18 1985-05-31 Richardson Merrell Inc 4-aroyl-imidazol-2-one derivatives;pharmaceutical compositions
PH18106A (en) * 1981-02-18 1985-03-21 Merrell Dow Pharma Novel-4-aroylimidazol-2-ones

Also Published As

Publication number Publication date
GB2110669B (en) 1985-04-11
DK488482A (da) 1983-05-05
DE3275995D1 (de) 1987-05-14
IE54265B1 (en) 1989-08-02
IL67133A0 (en) 1983-03-31
ES8405374A1 (es) 1984-06-16
KR840002362A (ko) 1984-06-25
ES517042A0 (es) 1984-06-16
EP0079050B1 (en) 1987-04-08
CA1175829A (en) 1984-10-09
JPS5885865A (ja) 1983-05-23
GR77375B (enExample) 1984-09-11
US4410540A (en) 1983-10-18
NO823648L (no) 1983-05-05
AU9011182A (en) 1983-05-12
GB2110669A (en) 1983-06-22
ATE26443T1 (de) 1987-04-15
NZ202350A (en) 1986-04-11
JPH0435465B2 (enExample) 1992-06-11
IE822621L (en) 1983-05-04
EP0079050A1 (en) 1983-05-18
PH19029A (en) 1985-12-06
ZA827974B (en) 1983-08-31
AU552310B2 (en) 1986-05-29

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