KR880001638B1 - 항종양성 항생물질 루조펩틴 e₂ 및 그 제조방법 - Google Patents

항종양성 항생물질 루조펩틴 e₂ 및 그 제조방법 Download PDF

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Publication number
KR880001638B1
KR880001638B1 KR1019840000383A KR840000383A KR880001638B1 KR 880001638 B1 KR880001638 B1 KR 880001638B1 KR 1019840000383 A KR1019840000383 A KR 1019840000383A KR 840000383 A KR840000383 A KR 840000383A KR 880001638 B1 KR880001638 B1 KR 880001638B1
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KR
South Korea
Prior art keywords
luzopeptin
methionine
cysteine
strain
medium
Prior art date
Application number
KR1019840000383A
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English (en)
Korean (ko)
Other versions
KR840007106A (ko
Inventor
에이. 클라리즈 차알스
슈미츠 헨리
더블유. 도일 테렌스
에프. 컴머 마리안
Original Assignee
브리스톨-마이어즈 컴페니
아이삭 자아코브스키
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 브리스톨-마이어즈 컴페니, 아이삭 자아코브스키 filed Critical 브리스톨-마이어즈 컴페니
Publication of KR840007106A publication Critical patent/KR840007106A/ko
Application granted granted Critical
Publication of KR880001638B1 publication Critical patent/KR880001638B1/ko

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019840000383A 1983-01-31 1984-01-28 항종양성 항생물질 루조펩틴 e₂ 및 그 제조방법 KR880001638B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46257783A 1983-01-31 1983-01-31
US462.577 1983-01-31
US462577 1983-01-31

Publications (2)

Publication Number Publication Date
KR840007106A KR840007106A (ko) 1984-12-05
KR880001638B1 true KR880001638B1 (ko) 1988-09-03

Family

ID=23836950

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840000383A KR880001638B1 (ko) 1983-01-31 1984-01-28 항종양성 항생물질 루조펩틴 e₂ 및 그 제조방법

Country Status (15)

Country Link
JP (1) JPH0645638B2 (sv)
KR (1) KR880001638B1 (sv)
AU (1) AU566569B2 (sv)
BE (1) BE898807A (sv)
CA (1) CA1220746A (sv)
CH (1) CH663415A5 (sv)
DE (1) DE3403125A1 (sv)
FR (1) FR2540116B1 (sv)
GB (1) GB2134119B (sv)
GR (1) GR81749B (sv)
IT (1) IT1175927B (sv)
MY (1) MY8800015A (sv)
NL (1) NL8400237A (sv)
SE (1) SE464582B (sv)
ZA (1) ZA84613B (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643871A (en) * 1993-11-23 1997-07-01 Bristol-Meyers Squibb Company Antitumor antibiotics
GB2294265A (en) * 1994-10-20 1996-04-24 Merck & Co Inc Cyclic depsipeptides obtained from Actinomycete sp.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2050384B (en) * 1979-04-02 1983-04-07 Bristol Myers Co Antitumor antibacterial agents

Also Published As

Publication number Publication date
SE464582B (sv) 1991-05-13
JPS59173091A (ja) 1984-09-29
JPH0645638B2 (ja) 1994-06-15
SE8400450L (sv) 1984-08-01
GR81749B (sv) 1984-12-12
GB2134119A (en) 1984-08-08
DE3403125A1 (de) 1984-10-31
AU566569B2 (en) 1987-10-22
FR2540116B1 (fr) 1989-08-18
CH663415A5 (de) 1987-12-15
SE8400450D0 (sv) 1984-01-30
NL8400237A (nl) 1984-08-16
IT1175927B (it) 1987-08-12
IT8419348A0 (it) 1984-01-27
BE898807A (fr) 1984-07-31
GB2134119B (en) 1986-04-30
ZA84613B (en) 1984-09-26
FR2540116A1 (fr) 1984-08-03
CA1220746A (en) 1987-04-21
AU2372184A (en) 1984-08-02
MY8800015A (en) 1988-12-31
GB8402410D0 (en) 1984-02-29
KR840007106A (ko) 1984-12-05

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