KR880001283A - 제약 조성물 - Google Patents

제약 조성물 Download PDF

Info

Publication number
KR880001283A
KR880001283A KR1019870007709A KR870007709A KR880001283A KR 880001283 A KR880001283 A KR 880001283A KR 1019870007709 A KR1019870007709 A KR 1019870007709A KR 870007709 A KR870007709 A KR 870007709A KR 880001283 A KR880001283 A KR 880001283A
Authority
KR
South Korea
Prior art keywords
aqueous solution
concentration
weight
taurolidine
polyol
Prior art date
Application number
KR1019870007709A
Other languages
English (en)
Other versions
KR950009096B1 (ko
Inventor
빌헬름 피트만 롤프
Original Assignee
원본미기재
에데. 가이스틀리히 존네 아.게.퓌어 케미쉐인두스트리
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 원본미기재, 에데. 가이스틀리히 존네 아.게.퓌어 케미쉐인두스트리 filed Critical 원본미기재
Publication of KR880001283A publication Critical patent/KR880001283A/ko
Application granted granted Critical
Publication of KR950009096B1 publication Critical patent/KR950009096B1/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

내용 없음

Description

제약 조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (10)

  1. 비경구적으로 허용되는 폴리올과 함께 유효 농도의 타우롤리딘 및(또는) 타우륨탐을 함유하는 수용액.
  2. 제1항에 있어서, 폴리올이 글리세롤, 당 또는 알코올인 수용액.
  3. 제2항에 있어서, 당 알코올이 소트비톨 또는 크실리톨인 수용액.
  4. 제1항에 있어서, 폴리올이 글루코오스인 수용액.
  5. 제1항에 있어서, 폴리올이 과당인 수용액.
  6. 전항 중 어느 하나의 항에 있어서, 타우롤리딘의 농도가 1 내지 50중량%이고(또는) 타우롤탐의 농도가 1내지 7.5중량%인 수용액.
  7. 전항 중 어느 하나의 항에 있어서, 타우롤리딘의 농도가 2 내지 3중량%이고(또는) 타우롤탐의 농도가 3 내지 5중량%인 수용액.
  8. 제7항에 있어서, 3 내지 4중량%의 농도의 타우롤리딘 및 15 내지 25중량% 농도의 글루코오스로 되는 수용액.
  9. 전항 중 어느 하나의 항에 있어서, 추가로 전해질 및(또는) 하나 이상의 아미노산 및(또는) 미량 원소 및 비타민으로 되는 수용액.
  10. 타우롤리딘 및(또는) 타우롤탐을 폴리올의 멸균 수용액 중에 용해시키는 것을 특징으로 하는 전항 중 어느 하나의 항의 수용액의 제조방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019870007709A 1986-07-17 1987-07-16 타우롤리딘 또는 타우룰탐 수용액 KR950009096B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB8617482 1986-07-17
GB86-17482 1986-07-17
GB868617482A GB8617482D0 (en) 1986-07-17 1986-07-17 Pharmaceutical composition

Publications (2)

Publication Number Publication Date
KR880001283A true KR880001283A (ko) 1988-04-22
KR950009096B1 KR950009096B1 (ko) 1995-08-14

Family

ID=10601226

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870007709A KR950009096B1 (ko) 1986-07-17 1987-07-16 타우롤리딘 또는 타우룰탐 수용액

Country Status (9)

Country Link
EP (1) EP0253662B1 (ko)
JP (1) JP2550356B2 (ko)
KR (1) KR950009096B1 (ko)
AT (1) ATE58294T1 (ko)
AU (1) AU604031B2 (ko)
CA (1) CA1287300C (ko)
DE (1) DE3766175D1 (ko)
ES (1) ES2026184T3 (ko)
GB (1) GB8617482D0 (ko)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU614170B2 (en) * 1988-08-26 1991-08-22 Minnesota Mining And Manufacturing Company A steam sensitive composition and a sterilization indicator composition containing the same
US6479481B1 (en) 1999-06-04 2002-11-12 Ed. Geistlich Soehne Ag Fur Chemische Industrie Methods and compositions for treating primary and secondary tumors of the central nervous system (CNS)
US20030027818A1 (en) 2001-04-03 2003-02-06 Redmond H. Paul Treatment of cancers
US8304390B2 (en) 1997-07-31 2012-11-06 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method of treatment for preventing or reducing tumor growth in the liver of patient
CA2306875C (en) * 1997-10-24 2011-01-04 John P. Blass Nutritional supplement for cerebral metabolic insufficiencies
FR2771928B1 (fr) * 1997-12-05 2001-04-13 Jean Noel Thorel Composition comprenant des derives de taurine ; son utilisation comme agent conservateur d'un produit alimentaire, ou pharmaceutique, topique ou cosmetique
US6117868A (en) * 1998-09-16 2000-09-12 Ed. Geistlich Sohne Ag Fur Chemische Industrie Treatment of gastrointestinal ulcers or gastritis caused by microbial infection
US6821968B2 (en) * 2001-09-26 2004-11-23 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Stable taurolidine electrolyte solutions
US7892530B2 (en) 1999-06-04 2011-02-22 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of tumor metastases and cancer
US8030301B2 (en) 1999-06-04 2011-10-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of cancers with methylol-containing compounds and at least one electrolyte
US7345039B2 (en) 1999-06-04 2008-03-18 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer
CA2696185C (en) 1999-12-06 2014-09-23 Geistlich Pharma Ag Use of taurolidine and derivatives thereof in the treatment of cancer by induction of apoptosis
CN100519525C (zh) 1999-12-06 2009-07-29 葛兰素集团有限公司 芳香砜类及其医疗用途
JP5280603B2 (ja) 2001-10-01 2013-09-04 ガイストリッヒ ファーマ アーゲー 転移阻害のための方法
DE07825069T1 (de) 2006-09-07 2010-04-08 Ed Geistlich Söhne Ag Für Chemische Industrie Verfahren zur behandlung von knochenkrebs
ES2644870T3 (es) 2012-06-18 2017-11-30 Geistlich Pharma Ag Derivados de oxatiazina como agentes antibacterianos y anticancerígenos
DK3233813T3 (da) 2014-12-19 2022-03-07 Geistlich Pharma Ag Fremgangsmåder til fremstilling af oxathiazin-lignende forbindelser
ES2945712T3 (es) 2016-03-18 2023-07-06 Geistlich Pharma Ag Método de tratamiento de cáncer de mama triple negativo
AU2022267897A1 (en) 2021-04-29 2023-11-02 Geistlich Pharma Ag Antimicrobial and anticancer agents
WO2024028846A1 (en) 2022-08-05 2024-02-08 Geistlich Pharma Ag Combination therapy for treating cancers

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH600878A5 (ko) * 1975-04-28 1978-06-30 Gaba Ag
DE2731013C2 (de) * 1977-07-08 1982-07-15 Lentia Gmbh Verfahren zur Herstellung einer wäßrigen Infusionslösung
US4296130A (en) * 1979-08-30 1981-10-20 Herschler R J Methylsulfonylmethane and methods of use
JPS58116413A (ja) * 1981-12-29 1983-07-11 Nippon Kayaku Co Ltd 静注用総合ビタミン剤
GB8328111D0 (en) * 1983-10-20 1983-11-23 Geistlich Soehne Ag Chemical compounds
JPS60246313A (ja) * 1984-05-22 1985-12-06 Yamanouchi Pharmaceut Co Ltd 塩酸ニカルジピンの注射剤およびその製法

Also Published As

Publication number Publication date
ES2026184T3 (es) 1992-04-16
DE3766175D1 (de) 1990-12-20
AU604031B2 (en) 1990-12-06
JP2550356B2 (ja) 1996-11-06
CA1287300C (en) 1991-08-06
EP0253662B1 (en) 1990-11-14
EP0253662A1 (en) 1988-01-20
AU7578587A (en) 1988-01-21
JPS6372626A (ja) 1988-04-02
KR950009096B1 (ko) 1995-08-14
GB8617482D0 (en) 1986-08-28
ATE58294T1 (de) 1990-11-15

Similar Documents

Publication Publication Date Title
KR880001283A (ko) 제약 조성물
ATE66614T1 (de) Insulinzubereitung fuer nicht-parenterale verabreichung.
KR830005849A (ko) 수중에서 이버멕틴의 용매화
FI880510A0 (fi) Menetelmä lääkeaineena käyttökelpoisen tiatsolidinonin johdannaisen valmistamiseksi
FI921087A0 (fi) Nya estrar av tienylkarboxylsyror och aminoalkoholer, deras kvaterniseringsprodukter och framstaellning och anvaendning av naemnda foereningar.
DK154987A (da) Farmaceutisk praeparat med forlaenget frigoerelse og fremstilling deraf
ES2130111T3 (es) Derivados de ciclohexano, preparaciones que los contienen y su utilizacion.
KR910005878A (ko) 미토마이신 c의 안정용액
BE905528A (fr) Compositions antibiotiques.
KR900006323A (ko) 시스 3-아미노-4-[2-(2-푸릴)에트-1-일]-1-메톡시카보닐메틸-아제티딘-2-온의 분할방법 및 그의 말산염.
KR900002774A (ko) 주사제
KR880005144A (ko) 올리고당의 제조법
DE3772403D1 (de) Zitronensaeurederivate als emulgatoren fuer die emulsationspolymerisation.
KR860002269A (ko) 비경구용 액제의 제조방법
BR8504700A (pt) Membrana incluindo uma folha elastomera de borracha liquida,processo para sua preparacao,composicao assim obtida bem como emprego da mesma
ES2037691T3 (es) Colirio liquido preparado con un contenido de acido cromoglicinico.
KR970027315A (ko) 글루타민산 나트륨의 제조 방법
KR890017325A (ko) 수정용액의 제조방법
KR910009258A (ko) 니트록시닐과 레바미솔 복합주사제의 제조방법
KR880000094A (ko) 위염치료제
KR910007856A (ko) 질산(12hno₃)을 이용한 수산[(cooh)₂₂2h₂o)]의 제조방법
KR870000917A (ko) 6-피페리디노(Piperidine)-2,4-디아미노피리미딘(diaminopyrimidinc)-3-옥사이드(oxide)의 외용액제 제조방법
KR860000873A (ko) 살균 소독용 의약품 제조방법
KR880000109A (ko) 내용 고형제(의약품)의 살균 저장방법
KR870010069A (ko) 모라노린 유도체의 제법

Legal Events

Date Code Title Description
E902 Notification of reason for refusal
A201 Request for examination
E902 Notification of reason for refusal
G160 Decision to publish patent application
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
LAPS Lapse due to unpaid annual fee