KR880000970B1 - 생물학적 유용성이 높은 경구용 약학적 조성물의 제조방법 - Google Patents

생물학적 유용성이 높은 경구용 약학적 조성물의 제조방법 Download PDF

Info

Publication number
KR880000970B1
KR880000970B1 KR8203134A KR820003134A KR880000970B1 KR 880000970 B1 KR880000970 B1 KR 880000970B1 KR 8203134 A KR8203134 A KR 8203134A KR 820003134 A KR820003134 A KR 820003134A KR 880000970 B1 KR880000970 B1 KR 880000970B1
Authority
KR
South Korea
Prior art keywords
water
drug
oil
unsaturated fatty
fatty acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR8203134A
Other languages
English (en)
Korean (ko)
Other versions
KR840000233A (ko
Inventor
시메수 모또야마
사또시 사또
세이이찌 우메다
히로쓰네 야수미
에미꼬 수도
다꾸이찌 쯔지노
아끼라 아까자와
Original Assignee
후꾸시마 야스유기
후로인트 산교 가부시끼 가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP10977781A external-priority patent/JPS5813508A/ja
Priority claimed from JP17516881A external-priority patent/JPS5877810A/ja
Application filed by 후꾸시마 야스유기, 후로인트 산교 가부시끼 가이샤 filed Critical 후꾸시마 야스유기
Publication of KR840000233A publication Critical patent/KR840000233A/ko
Application granted granted Critical
Publication of KR880000970B1 publication Critical patent/KR880000970B1/ko
Expired legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR8203134A 1981-07-14 1982-07-14 생물학적 유용성이 높은 경구용 약학적 조성물의 제조방법 Expired KR880000970B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP109777/81 1981-07-14
JP10977781A JPS5813508A (ja) 1981-07-14 1981-07-14 ポリグリセロール飽和脂肪酸エステルを含む経口薬剤組成物
JP109777/81? 1981-07-14
JP17516881A JPS5877810A (ja) 1981-11-01 1981-11-01 ポリグリセロ−ル不飽和脂肪酸エステルを含む経口薬剤組成物
JP175168/81 1981-11-01
JP175168/81? 1981-11-11

Publications (2)

Publication Number Publication Date
KR840000233A KR840000233A (ko) 1984-02-18
KR880000970B1 true KR880000970B1 (ko) 1988-06-07

Family

ID=26449492

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8203134A Expired KR880000970B1 (ko) 1981-07-14 1982-07-14 생물학적 유용성이 높은 경구용 약학적 조성물의 제조방법

Country Status (4)

Country Link
US (1) US4751241A (enExample)
KR (1) KR880000970B1 (enExample)
CH (1) CH652307A5 (enExample)
DE (1) DE3224619A1 (enExample)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3582439D1 (de) * 1984-01-28 1991-05-16 Roshdy Ismail Mittel zur behandlung von herzerkrankungen.
US5948769A (en) * 1984-01-28 1999-09-07 Ismail; Roshdy Agent for treating heart diseases
US5229164A (en) * 1985-12-19 1993-07-20 Capsoid Pharma Gmbh Process for producing individually dosed administration forms
SE457693B (sv) * 1986-07-01 1989-01-23 Drilletten Ab Komposition med reglerad frigoering vari ett biologiskt material aer loest eller dispergerat i en l2-fas
JP2643217B2 (ja) * 1988-01-22 1997-08-20 エーザイ株式会社 脂溶性物質水性液
AU645003B2 (en) * 1988-11-08 1994-01-06 Takeda Chemical Industries Ltd. Sustained release preparations
JP2893191B2 (ja) * 1988-11-08 1999-05-17 武田薬品工業株式会社 放出制御性マトリックス剤
JPH02188523A (ja) * 1989-01-13 1990-07-24 M S C:Kk 睡眠時無呼吸症治療薬
ATE104862T1 (de) * 1989-08-03 1994-05-15 Hisamitsu Pharmaceutical Co Hautcremezubereitung zur aeusserlichen verwendung.
IE65045B1 (en) * 1990-04-28 1995-10-04 Takeda Chemical Industries Ltd Granulated preparations and method of producing the same
US5179122A (en) * 1991-02-11 1993-01-12 Eastman Kodak Company Nutritional supplement containing vitamin e
DE69324523T2 (de) * 1992-06-12 1999-09-09 Kao Corp. Badezusatzzusammensetzung enthaltend oberflächenaktive Mittel enthaltende nahtlose Kapsel und Verfahren zur Herrstellung der Kapsel
IT1256386B (it) * 1992-11-13 1995-12-04 Luigi Boltri Composizioni farmaceutiche comprendenti un farmaco,una sostanza polimerica reticolata,un olio ed un agente tensioattivo
AU5832794A (en) * 1993-01-06 1994-08-15 T.S. Consult Aps Medium comprising a pharmacological/biological active substance
DE19647352C2 (de) * 1996-11-15 2000-06-29 Aqua Nova Getraenketechnologie Nicht alkoholisches Getränk mit einem Gehalt an Q 10
DE19722405A1 (de) * 1997-05-28 1998-12-03 Ifac Inst Fuer Angewandte Coll Einkapseln von wasserunlöslichen Wirkstoffen mit amphiphilem Charakter
US6531150B1 (en) * 1997-10-30 2003-03-11 Morishita Jintan Co., Ltd. Encapsulated unsaturated fatty acid substance and method for producing the same
DE69942205D1 (de) 1998-08-13 2010-05-12 Cima Labs Inc Microemulsionen als feste dosisformen zur oralen verabreichung
IT1304406B1 (it) * 1998-10-21 2001-03-19 Danital Italia S R L Preparazione per la veicolazione di principi attivi basata su acidigrassi polinsaturi del gruppo omega 3.
CN1402629A (zh) 1999-12-23 2003-03-12 辉瑞产品公司 提供提高的药物浓度的药物组合物
US6692771B2 (en) * 2001-02-23 2004-02-17 Cima Labs Inc. Emulsions as solid dosage forms for oral administration
DE10133305B4 (de) * 2001-07-12 2004-06-03 Aquanova German Solubilisate Technologies (Agt) Gmbh Ubichinon Konzentrat
JP3549197B2 (ja) * 2001-08-10 2004-08-04 日清ファルマ株式会社 ユビキノン含有製剤
TW200302056A (en) * 2002-01-18 2003-08-01 Kaneka Corp Method for stabilizing reduced coenzyme Q10 and composition therefor
KR100724326B1 (ko) * 2003-01-17 2007-06-04 타이요 카가꾸 가부시키가이샤 코엔자임 ｑ10 함유 조성물
ES2665464T3 (es) * 2003-03-28 2018-04-25 Sigmoid Pharma Limited Forma de dosificación oral sólida que contiene microcápsulas sin costuras
EP1802287A2 (en) * 2004-09-27 2007-07-04 Sigmoid Biotechnologies Limited Minicapsule formulations
US8480797B2 (en) 2005-09-12 2013-07-09 Abela Pharmaceuticals, Inc. Activated carbon systems for facilitating use of dimethyl sulfoxide (DMSO) by removal of same, related compounds, or associated odors
AU2006291134C1 (en) 2005-09-12 2013-08-15 Abela Pharmaceuticals, Inc. Systems for removing dimethyl sulfoxide (DMSO) or related compounds, or odors associated with same
US8435224B2 (en) 2005-09-12 2013-05-07 Abela Pharmaceuticals, Inc. Materials for facilitating administration of dimethyl sulfoxide (DMSO) and related compounds
WO2007033082A2 (en) 2005-09-12 2007-03-22 Abela Pharmaceuticals, Inc. Compositions comprising dimethyl sulfoxide (dmso)
US8506956B2 (en) * 2005-10-31 2013-08-13 Kaneka Corporation Method for stabilizing reduced coenzyme Q10
JP5128801B2 (ja) * 2006-10-16 2013-01-23 フロイント産業株式会社 高水分散性粉末とその製造方法
ES2393814T3 (es) 2007-04-04 2012-12-28 Sigmoid Pharma Limited Una composición farmacéutica oral
CA2685118C (en) * 2007-04-26 2016-11-01 Sigmoid Pharma Limited Manufacture of multiple minicapsules
WO2008132712A2 (en) * 2007-05-01 2008-11-06 Sigmoid Pharma Limited Combination pharmaceutical compositions
WO2009001786A1 (ja) * 2007-06-22 2008-12-31 Kaneka Corporation 生理活性物質含有組成物
US20110123505A1 (en) * 2007-08-22 2011-05-26 Kaneka Corporation Method of producing reduced coenzyme q10 and method of stabilizing the same
JPWO2009025372A1 (ja) * 2007-08-23 2010-11-25 株式会社カネカ 還元型補酵素ｑ１０含有組成物及びその安定化方法
BRPI0921494A2 (pt) * 2008-11-03 2018-10-30 Prad Reasearch And Development Ltd método de planejamento de uma operação de amostragem para uma formação subterrãnea, método de contolar uma operação de amostragem de formação subterrânea, método de controlar uma operação de perfuração para uma formação subterrãnea, e método de realizar uma amostragem durante a operação de perfuração.
ES2530049T3 (es) 2009-05-18 2015-02-26 Sigmoid Pharma Limited Composición que comprende gotas de aceite
CN102573802A (zh) 2009-08-12 2012-07-11 希格默伊德药业有限公司 包含聚合物基质和油相的免疫调节组合物
US9839609B2 (en) 2009-10-30 2017-12-12 Abela Pharmaceuticals, Inc. Dimethyl sulfoxide (DMSO) and methylsulfonylmethane (MSM) formulations to treat osteoarthritis
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
BR112016018561A2 (pt) * 2014-02-13 2017-08-08 Clariant Int Ltd Preparação de poligliceróis
JP6716582B2 (ja) 2014-11-07 2020-07-01 サブリミティ・セラピューティクス・リミテッドＳｕｂｌｉｍｉｔｙ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｌｉｍｉｔｅｄ シクロスポリンを含む組成物
JP7560982B2 (ja) * 2020-09-18 2024-10-03 日清ファルマ株式会社 コエンザイムｑ１０含有水溶性組成物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932634A (en) * 1973-06-28 1976-01-13 Pfizer Inc. High potency vitamin water dispersible formulations
US3966632A (en) * 1974-06-06 1976-06-29 G. D. Searle & Co. Vegetable oil emulsion
US4073943A (en) * 1974-09-11 1978-02-14 Apoteksvarucentralen Vitrum Ab Method of enhancing the administration of pharmalogically active agents
US3996355A (en) * 1975-01-02 1976-12-07 American Home Products Corporation Permanent suspension pharmaceutical dosage form
DE2907460A1 (de) * 1978-03-07 1979-09-13 Sandoz Ag Neue resorbierbare galenische kompositionen
JPS574916A (en) * 1980-05-28 1982-01-11 Furointo Sangyo Kk Activation of medical preparation
US4327076A (en) * 1980-11-17 1982-04-27 Life Savers, Inc. Compressed chewable antacid tablet and method for forming same
US4327077A (en) * 1981-05-29 1982-04-27 Life Savers, Inc. Compressed chewable antacid tablet and method for forming same

Also Published As

Publication number Publication date
DE3224619C2 (enExample) 1990-10-04
US4751241A (en) 1988-06-14
KR840000233A (ko) 1984-02-18
CH652307A5 (de) 1985-11-15
DE3224619A1 (de) 1983-05-19

Similar Documents

Publication Publication Date Title
KR880000970B1 (ko) 생물학적 유용성이 높은 경구용 약학적 조성물의 제조방법
US5672358A (en) Controlled release aqueous emulsion
JPS5813508A (ja) ポリグリセロール飽和脂肪酸エステルを含む経口薬剤組成物
AU648573B2 (en) Self-emulsifying glasses
JP2006511536A (ja) 水貧溶性薬物のバイオアベイラビリティーを改善する自由流動性固形製剤およびその製造方法
KR100425226B1 (ko) 아세클로페낙을 함유하는 경제적인 경구용 제제의 조성 및제법
JPS6230965B2 (enExample)
EP0985411B1 (en) Sterol esters in tableted solid dosage forms
KR100887034B1 (ko) 부틸프탈라이드 자가 에멀젼화 약물 전달 시스템, 그 제조방법 및 응용
CN112353845B (zh) 含中药挥发油的热熔挤出组合物及其制备方法和药物制剂
US5189066A (en) Pharmaceutical compositions of tebufelone
EP0431659B1 (en) Pharmaceutical compositions of tebufelone
TW202128150A (zh) ３＇—［（２ｚ）—［１—（３，４—二甲基苯基）—１，５—二氫—３—甲基—５—側氧基—４ｈ—吡唑—４—亞基］肼基］—２＇—羥基—［１，１＇—聯苯基］—３—甲酸及其鹽配製物
MXPA99008044A (en) Sterol esters in solid dose forms as table

Legal Events

Date Code Title Description
PA0109 Patent application

St.27 status event code: A-0-1-A10-A12-nap-PA0109

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

PG1605 Publication of application before grant of patent

St.27 status event code: A-2-2-Q10-Q13-nap-PG1605

PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U11-oth-PR1002

Fee payment year number: 1

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 7

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 8

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 9

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 10

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 11

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 12

PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20000608

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20000608

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000