KR870009729A - 재흡수성 다공질 인산 3칼슘의 제조방법 - Google Patents

재흡수성 다공질 인산 3칼슘의 제조방법 Download PDF

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Publication number
KR870009729A
KR870009729A KR870003588A KR870003588A KR870009729A KR 870009729 A KR870009729 A KR 870009729A KR 870003588 A KR870003588 A KR 870003588A KR 870003588 A KR870003588 A KR 870003588A KR 870009729 A KR870009729 A KR 870009729A
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South Korea
Prior art keywords
tricalcium phosphate
antibiotic
resorbable
filler
porous tricalcium
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KR870003588A
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English (en)
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KR950003699B1 (ko
Inventor
딩글다인 엘비라
바흐리크 헬무트
보쵸카우스키 맨프레트
모델모크 귄터
Original Assignee
감스
메르크 파텐트 게젤샤프트 미트 베슈랭크터 하프퉁
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Publication of KR870009729A publication Critical patent/KR870009729A/ko
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Publication of KR950003699B1 publication Critical patent/KR950003699B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/21—Acids
    • A61L2300/214—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Biomedical Technology (AREA)
  • Materials For Medical Uses (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Medicinal Preparation (AREA)
  • Aftertreatments Of Artificial And Natural Stones (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)

Abstract

내용 없음

Description

재흡수성 다공질 인산 3칼슘의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (8)

  1. 폴리아크릴레이트 및/또는 폴리메타아크릴레이트를 기재로한 삽입물질의 첨가재로서 적합하고, 기공을 체내에서 내성을 갖는 재흡수성 충전재로 채운 재흡수성 다공질 인산 3칼슘에 있어서, 충전재가 적어도 2종의 성불으로 구성되고, 이중 성분 1종은 항생물질인 것을 특징으로 하는 재흡수성 다공질 인산 3칼슘.
  2. 제1항에 있어서, 항생물질이외에, 아미노산을 함유하는 것을 특징으로 하는 재흡수성 다공질 인산 3칼슘.
  3. 제1항 또는 제2항에서 있어서, 항생물질로서 아미노들리시드 항생제를 함유하는 것을 특징으로 하는 제흡수성 다공질 인산 3칼슘.
  4. 폴리아크릴레이트 및/또는 폴리메타아크릴레이트를 기재로한 삽입물질용 첨가제로서 적합하고, 기공을 체내에서 내성을 갖는 재흡수성 충전재로 채운 재흡수성 다공질 인산 3칼슘의 제조방법에 있어서, 다공질 인산 3칼슘을 항생물질 및 다른 충전재의 용액과 접촉반응시키고 용매는 제거하는 것을 특징으로 하는 재흡수성 다공질 인산 3칼슘의 제조방법.
  5. 제4항에 있어서, 인산 3칼슘을 항생물질 및 다른 충전재의 용액에 현탁시키고 현탁액을 분무-건조하는 것을 특징으로 하는 재흡수성 다공질 인산 3칼슘의 제조방법.
  6. 제4항 또는 제5항에 있어서, 항생물질로서 아미노글리코시드 항생제를 사용하고 다른 충전재로서 아미노산을 사용하는 것을 특징으로 하는 재흡수성 다공질 인산 3칼슘의 제조방법.
  7. 폴리아크릴레이트 및/또는 폴리메타아크릴레이트를 기재로한 미분한 고체 성분 및 액체 모노머 성분을 즉시 사용 팩 유니트에 함유하는 골 시멘트 제조용 전구체에 있어서, 고체성분이 제1항에 따른 인산 3칼슘 5내지 30중량%를 함유하는 것을 특징으로 하는 전구체.
  8. 폴리아크리릴레이트 및/또는 폴리메타아크릴레이트를 기재로한 삽입물질, 특히 골 시멘트에 있어서, 이들이 제1항에 따른 인산 3칼슘 3내지 20중량%를 함유하는 것을 특징으로 하는 삽입물질.
    ※참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019870003588A 1986-04-18 1987-04-15 재흡수성 다공질 인산 3 칼슘의 제조방법 KR950003699B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863613213 DE3613213A1 (de) 1986-04-18 1986-04-18 Tricalciumphosphat fuer implantationsmaterialien
DE3613213.6 1986-04-18

Publications (2)

Publication Number Publication Date
KR870009729A true KR870009729A (ko) 1987-11-30
KR950003699B1 KR950003699B1 (ko) 1995-04-17

Family

ID=6299037

Family Applications (1)

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KR1019870003588A KR950003699B1 (ko) 1986-04-18 1987-04-15 재흡수성 다공질 인산 3 칼슘의 제조방법

Country Status (12)

Country Link
US (1) US4869906A (ko)
EP (1) EP0242672B1 (ko)
JP (1) JP2552483B2 (ko)
KR (1) KR950003699B1 (ko)
AT (1) ATE81785T1 (ko)
AU (1) AU603356B2 (ko)
CA (1) CA1276558C (ko)
DE (2) DE3613213A1 (ko)
ES (1) ES2044855T3 (ko)
HU (1) HU198384B (ko)
IE (1) IE59765B1 (ko)
ZA (1) ZA872762B (ko)

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Also Published As

Publication number Publication date
ZA872762B (en) 1987-11-25
ATE81785T1 (de) 1992-11-15
DE3782357D1 (en) 1992-12-03
EP0242672A3 (en) 1990-01-17
EP0242672A2 (de) 1987-10-28
KR950003699B1 (ko) 1995-04-17
JPS62254764A (ja) 1987-11-06
AU7116887A (en) 1987-10-22
EP0242672B1 (de) 1992-10-28
JP2552483B2 (ja) 1996-11-13
HU198384B (en) 1989-10-30
AU603356B2 (en) 1990-11-15
US4869906A (en) 1989-09-26
IE871019L (en) 1987-10-18
ES2044855T3 (es) 1994-01-16
IE59765B1 (en) 1994-03-23
CA1276558C (en) 1990-11-20
HUT44169A (en) 1988-02-29
DE3613213A1 (de) 1987-10-22

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