KR860008139A - 2,3- 디페닐- 치환된 γ- 니트릴- 에스테르의 폐환생성물을 제조하는 방법 - Google Patents
2,3- 디페닐- 치환된 γ- 니트릴- 에스테르의 폐환생성물을 제조하는 방법 Download PDFInfo
- Publication number
- KR860008139A KR860008139A KR1019860002571A KR860002571A KR860008139A KR 860008139 A KR860008139 A KR 860008139A KR 1019860002571 A KR1019860002571 A KR 1019860002571A KR 860002571 A KR860002571 A KR 860002571A KR 860008139 A KR860008139 A KR 860008139A
- Authority
- KR
- South Korea
- Prior art keywords
- alkyl
- nitrile
- diphenyl
- ester
- substituted
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title claims 2
- 238000007363 ring formation reaction Methods 0.000 title claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- 239000001257 hydrogen Substances 0.000 claims 5
- 229910052784 alkaline earth metal Inorganic materials 0.000 claims 3
- 150000002431 hydrogen Chemical group 0.000 claims 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 2
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 claims 2
- 150000001342 alkaline earth metals Chemical class 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 2
- 125000004769 (C1-C4) alkylsulfonyl group Chemical group 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 125000004423 acyloxy group Chemical group 0.000 claims 1
- 239000003513 alkali Substances 0.000 claims 1
- 229910052783 alkali metal Inorganic materials 0.000 claims 1
- 150000001340 alkali metals Chemical class 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- -1 phenoxy, benzyloxy Chemical group 0.000 claims 1
- 230000002685 pulmonary effect Effects 0.000 claims 1
- 239000007858 starting material Substances 0.000 claims 1
- 239000002699 waste material Substances 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8505123 | 1985-04-04 | ||
| FR8505123A FR2587339B1 (fr) | 1985-04-04 | 1985-04-04 | Nouveaux medicaments constitues par des derives-2,3 ou -3,4 diphenyles des esters g-nitriles ou leurs produits de cyclisation et procedes pour les preparer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR860008139A true KR860008139A (ko) | 1986-11-12 |
Family
ID=9317941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019860002571A KR860008139A (ko) | 1985-04-04 | 1986-04-04 | 2,3- 디페닐- 치환된 γ- 니트릴- 에스테르의 폐환생성물을 제조하는 방법 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4785007A (es) |
| EP (1) | EP0203308A2 (es) |
| JP (1) | JPS61229854A (es) |
| KR (1) | KR860008139A (es) |
| AU (1) | AU5561786A (es) |
| DK (1) | DK151586A (es) |
| ES (4) | ES8802219A1 (es) |
| FR (1) | FR2587339B1 (es) |
| GR (1) | GR860891B (es) |
| PT (1) | PT82333B (es) |
| ZA (1) | ZA862458B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI875101A (fi) * | 1986-12-03 | 1988-06-04 | Tanabe Seiyaku Co | Laktamderivat och preparat innehaollande dessa. |
| JP4943429B2 (ja) * | 2005-07-22 | 2012-05-30 | メルク・シャープ・エンド・ドーム・コーポレイション | カリウムチャネル阻害剤 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE765203C (de) * | 1939-08-02 | 1953-06-01 | Ig Farbenindustrie Ag | Verfahren zur Herstellung von Piperidonen und Piperidinen |
| US3468893A (en) * | 1966-03-14 | 1969-09-23 | Ciba Geigy Corp | 1-substituted-diphenyl-azacycloalkenes |
| US3956314A (en) * | 1970-07-24 | 1976-05-11 | U.C.B., Societe Anonyme | Derivatives of 2-pyrrolidinone |
| US3814771A (en) * | 1970-11-19 | 1974-06-04 | T Shen | 5-phenyl-2-piperidones and 5-phenyl-2-thiopiperidones |
| US3718743A (en) * | 1970-11-19 | 1973-02-27 | Merck & Co Inc | 5-phenyl-2-piperidones and 5-phenyl-2-thiopiperidones in compositions and methods for treating pain, fever and inflammation |
| AU518986B2 (en) * | 1977-10-11 | 1981-10-29 | Takeda Chemical Industries Ltd. | Lactams |
-
1985
- 1985-04-04 FR FR8505123A patent/FR2587339B1/fr not_active Expired
-
1986
- 1986-03-27 EP EP86104231A patent/EP0203308A2/de not_active Withdrawn
- 1986-04-02 US US06/847,255 patent/US4785007A/en not_active Expired - Fee Related
- 1986-04-02 ES ES553642A patent/ES8802219A1/es not_active Expired
- 1986-04-03 GR GR860891A patent/GR860891B/el unknown
- 1986-04-03 JP JP61075679A patent/JPS61229854A/ja active Pending
- 1986-04-03 ZA ZA862458A patent/ZA862458B/xx unknown
- 1986-04-03 PT PT82333A patent/PT82333B/pt unknown
- 1986-04-03 DK DK151586A patent/DK151586A/da not_active IP Right Cessation
- 1986-04-03 AU AU55617/86A patent/AU5561786A/en not_active Abandoned
- 1986-04-04 KR KR1019860002571A patent/KR860008139A/ko not_active Application Discontinuation
-
1987
- 1987-07-16 ES ES557625A patent/ES8802490A1/es not_active Expired
- 1987-07-16 ES ES557626A patent/ES8802491A1/es not_active Expired
-
1988
- 1988-01-15 ES ES557801A patent/ES8802221A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GR860891B (en) | 1986-08-04 |
| ES8802219A1 (es) | 1988-04-16 |
| ES557625A0 (es) | 1988-07-01 |
| ES557626A0 (es) | 1988-07-01 |
| ES557801A0 (es) | 1988-04-16 |
| ES8802221A1 (es) | 1988-04-16 |
| ES553642A0 (es) | 1988-04-16 |
| DK151586A (da) | 1986-10-05 |
| JPS61229854A (ja) | 1986-10-14 |
| FR2587339B1 (fr) | 1988-08-05 |
| PT82333A (fr) | 1986-05-01 |
| US4785007A (en) | 1988-11-15 |
| ZA862458B (en) | 1986-11-26 |
| FR2587339A1 (fr) | 1987-03-20 |
| ES8802491A1 (es) | 1988-07-01 |
| EP0203308A2 (de) | 1986-12-03 |
| AU5561786A (en) | 1986-10-09 |
| PT82333B (fr) | 1988-04-07 |
| ES8802490A1 (es) | 1988-07-01 |
| DK151586D0 (da) | 1986-04-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |