KR860001790A - 프로카테롤 안정화 방법 - Google Patents
프로카테롤 안정화 방법 Download PDFInfo
- Publication number
- KR860001790A KR860001790A KR1019850005890A KR850005890A KR860001790A KR 860001790 A KR860001790 A KR 860001790A KR 1019850005890 A KR1019850005890 A KR 1019850005890A KR 850005890 A KR850005890 A KR 850005890A KR 860001790 A KR860001790 A KR 860001790A
- Authority
- KR
- South Korea
- Prior art keywords
- procaterol
- group
- ropo
- roso
- ammonium
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Quinoline Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (5)
- (1)산 대기하에서, 프로카테롤 및 그것의 제약학적으로 허용가능한 염으로 구성되는 그룹에서 선택된 최소한 하나의 반응물을, RCOOX, ROPO3X 및 ROSO3X(식중 R은 C5-20유기 래디칼이고 X는 일가금속 또는 암모늄)로 구성되는 그룹에서 선택된 최소한 안정화 시약과 접촉하고, (2)다음 일반식을 갖는 유도체를 회수하는〔식중 Y는 RCOOH, ROPO3H, ROSO3H에서 선택되고, R은 C5-20유기 래디칼〕것으로 구성된 프로카테롤의 내산화성 및 내습성 유도체를 생성하는 방법.
- 제1항에 있어서, R이 C10-15탄화수소 래디칼인 방법.
- 제2항에 있어서, X가 나트륨 및 암모늄에서 선택된 최소한 하나인 방법.
- 제3항에 있어서, R이 라우릴 그룹인 방법.
- 제4항에 있어서, 안정화 시약이 나트륨 라우릴 황산염인 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/641,631 US4616022A (en) | 1984-08-17 | 1984-08-17 | Procaterol stabilization |
US641,631 | 1984-08-17 | ||
US641.631 | 1984-08-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR860001790A true KR860001790A (ko) | 1986-03-22 |
KR900001175B1 KR900001175B1 (ko) | 1990-02-27 |
Family
ID=24573198
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019850005890A KR900001175B1 (ko) | 1984-08-17 | 1985-08-16 | 프로카테롤 안정화 방법 |
Country Status (14)
Country | Link |
---|---|
US (1) | US4616022A (ko) |
EP (1) | EP0171969A3 (ko) |
JP (1) | JPS6153267A (ko) |
KR (1) | KR900001175B1 (ko) |
AU (1) | AU572306B2 (ko) |
CA (1) | CA1265142A (ko) |
DK (1) | DK275885A (ko) |
ES (1) | ES8701164A1 (ko) |
FI (1) | FI852431L (ko) |
GR (1) | GR851649B (ko) |
NZ (1) | NZ212531A (ko) |
PH (1) | PH20805A (ko) |
PT (1) | PT80952B (ko) |
ZA (1) | ZA854636B (ko) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA875317B (en) * | 1986-08-01 | 1988-01-25 | Warner-Lambert Company | Transdermal compositions |
US4687776A (en) * | 1986-10-24 | 1987-08-18 | Warner-Lambert Company | Drug stabilization |
WO1988007036A1 (en) * | 1987-03-16 | 1988-09-22 | University Of Florida | LABILE KETONE DERIVATIVES OF 3-SUBSTITUTED-1-ALKYLAMINO-2-PROPANOLS AND THEIR USE AS beta-ADRENERGIC BLOCKERS |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1108320A (en) * | 1965-10-07 | 1968-04-03 | Shionogi & Co | Improvements in or relating to anti-microbial compositions |
FR5129M (fr) * | 1966-01-18 | 1967-06-05 | Olivier Paul Gaudin | Medicaments a base d'alkylsulfate d'homomyrtenyloxy-2 diethylamino-1 ethane |
US4022776A (en) * | 1974-01-31 | 1977-05-10 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxycarbostyril derivatives |
BE896423A (fr) * | 1983-04-11 | 1983-08-01 | Ct Europ De Rech S Therapeutiq | Nouveaux sels liposolubles de doxycycline et leur preparation |
-
1984
- 1984-08-17 US US06/641,631 patent/US4616022A/en not_active Expired - Fee Related
-
1985
- 1985-06-18 CA CA000484326A patent/CA1265142A/en not_active Expired - Fee Related
- 1985-06-18 DK DK275885A patent/DK275885A/da not_active Application Discontinuation
- 1985-06-19 ZA ZA854636A patent/ZA854636B/xx unknown
- 1985-06-19 FI FI852431A patent/FI852431L/fi not_active Application Discontinuation
- 1985-06-20 AU AU43881/85A patent/AU572306B2/en not_active Ceased
- 1985-06-24 NZ NZ212531A patent/NZ212531A/en unknown
- 1985-06-26 ES ES544571A patent/ES8701164A1/es not_active Expired
- 1985-07-04 GR GR851649A patent/GR851649B/el unknown
- 1985-07-10 JP JP60150329A patent/JPS6153267A/ja active Pending
- 1985-07-30 EP EP85305425A patent/EP0171969A3/en not_active Withdrawn
- 1985-08-14 PT PT80952A patent/PT80952B/pt not_active IP Right Cessation
- 1985-08-14 PH PH32630A patent/PH20805A/en unknown
- 1985-08-16 KR KR1019850005890A patent/KR900001175B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
GR851649B (ko) | 1985-11-26 |
NZ212531A (en) | 1988-02-12 |
KR900001175B1 (ko) | 1990-02-27 |
AU4388185A (en) | 1986-02-20 |
FI852431L (fi) | 1986-02-18 |
AU572306B2 (en) | 1988-05-05 |
CA1265142A (en) | 1990-01-30 |
FI852431A0 (fi) | 1985-06-19 |
ES8701164A1 (es) | 1986-11-16 |
ES544571A0 (es) | 1986-11-16 |
PH20805A (en) | 1987-04-21 |
DK275885A (da) | 1986-02-18 |
DK275885D0 (da) | 1985-06-18 |
EP0171969A3 (en) | 1987-11-04 |
US4616022A (en) | 1986-10-07 |
ZA854636B (en) | 1986-02-26 |
PT80952B (pt) | 1987-11-11 |
JPS6153267A (ja) | 1986-03-17 |
PT80952A (en) | 1985-09-01 |
EP0171969A2 (en) | 1986-02-19 |
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G160 | Decision to publish patent application | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
LAPS | Lapse due to unpaid annual fee |