KR850006926A - N-[4-(3-아미노프로필)아미노부틸]-2, 2-디히드록시 에탄아미드의 제조방법 - Google Patents

N-[4-(3-아미노프로필)아미노부틸]-2, 2-디히드록시 에탄아미드의 제조방법 Download PDF

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KR850006926A
KR850006926A KR1019850001212A KR850001212A KR850006926A KR 850006926 A KR850006926 A KR 850006926A KR 1019850001212 A KR1019850001212 A KR 1019850001212A KR 850001212 A KR850001212 A KR 850001212A KR 850006926 A KR850006926 A KR 850006926A
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South Korea
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formula
group
compound
producing
compound represented
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KR1019850001212A
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KR900001076B1 (ko
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요시히사 우메다 (외 5)
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구기다 미노루
타카라 슈조오 가부시키 가이샤 (외 1)
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C233/05—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음

Description

N-〔4-(3-아미노프로필)아미노부틸〕-2,2-디히드록시 에탄아미드의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (5)

  1. 하기 일반식(Ⅰ)도 표시되는 화합물의 적당한 C-C결합을 선택적으로 산화분열시킴을 특징으로 하는 하기 구조식(Ⅱ)로 표시되는 N-〔4-(3-아미노프로필)아미노부틸〕-2,2-디하이드록시에탄아미드의 제조방법.
    상기식에서, R1은 히드록시기 또는 아미노기(단, R1은 모두 아미노기가 될 수 없음)이고, R2는 수소 원자, 치환가능한 알킬기, 카르복실기, 치환가능한 알콕시카르보닐기 또는 카르바모일기이다.
  2. 제1항에 있어서, 일반식(Ⅰ)로 표시되는 화합물이 하기 구조식의 화합물인 구조식(Ⅱ)의 화합물의 제조방법.
  3. 제1항에 있어서, 일반식 (Ⅰ)로 표시되는 화합물이 하기 구조식의 화합물인 구조식(Ⅱ)의 화합물의 제조방법.
  4. 제1항에 있어서, 일반식 (Ⅰ)로 표시되는 화합물이 하기 구조식의 화합물인 구조식(Ⅱ)의 화합물의 제조방법.
  5. 하기 일반식(Ⅰ)로 표시되는 화합물의 적당한 C-C결합을 선택적으로 산화분열시켜 제조되는 하기 구조식(Ⅱ)의 에탄아미드를 하기 구조식 (XVI)의 W-구아니디노 지방산 아미드와 축합시킴을 특징으로 하는 하기 일반식(XV)의 화합물의 제조방법.
    상기식들에 있어서, R1은 히드록시기 또는 아미노기(단, R1은 모두 아니노기가 될 수 없음)이고, R2는 수소 원자, 치환가능한 알킬기, 카르복실기, 치환 가능한 알콕시 카르보닐기 또는 카르바모일기이며, n은 6 내지 8의 정수이다.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019850001212A 1984-02-29 1985-02-27 N-[4-(3-아미노프로필)아미노부틸]-2,2-디히드록시에탄아미드의 제조방법 KR900001076B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP36263 1984-02-29
JP59036263A JPS60181056A (ja) 1984-02-29 1984-02-29 Ν−〔４−（３−アミノプロピル）アミノブチル〕−２，２−ジヒドロキシエタンアミドの製造法

Publications (2)

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KR850006926A true KR850006926A (ko) 1985-10-25
KR900001076B1 KR900001076B1 (ko) 1990-02-26

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ID=12464879

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KR1019850001212A KR900001076B1 (ko) 1984-02-29 1985-02-27 N-[4-(3-아미노프로필)아미노부틸]-2,2-디히드록시에탄아미드의 제조방법

Country Status (16)

Country Link
US (1) US4603015A (ko)
JP (1) JPS60181056A (ko)
KR (1) KR900001076B1 (ko)
AR (1) AR240553A1 (ko)
AU (1) AU564211B2 (ko)
CA (1) CA1226004A (ko)
CH (1) CH665635A5 (ko)
CS (1) CS268666B2 (ko)
DE (1) DE3506330A1 (ko)
DK (1) DK168762B1 (ko)
ES (1) ES8700652A1 (ko)
FR (1) FR2563829B1 (ko)
GB (1) GB2155013B (ko)
HU (1) HU193738B (ko)
IT (1) IT1208798B (ko)
SE (1) SE469130B (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4576757A (en) * 1984-04-26 1986-03-18 Johnson & Johnson Baby Products Company Process for the preparation of monoacyl polyalkylene polyamines
JPS61129119A (ja) * 1984-11-13 1986-06-17 Microbial Chem Res Found 新規免疫抑制剤
ES2039213T3 (es) * 1986-04-04 1993-09-16 Microbial Chemistry Research Foundation Procedimiento para producir nuevos compuestos relacionados con espergualina.
US5002756A (en) * 1988-04-04 1991-03-26 Zaidanhojin Biseibutsu Kagakukenkyukai Method for relieving radiogenic or drug-induced side effects
JPH0776204B2 (ja) * 1988-07-01 1995-08-16 寳酒造株式会社 スパガリン類の精製法
US5196453A (en) * 1989-05-29 1993-03-23 Takara Shuzo Co., Ltd. Crystalline deoxyspergualin, process for its preparation and suppository containing the same
JPH078846B2 (ja) * 1989-05-29 1995-02-01 寳酒造株式会社 塩酸デオキシスパガリンのβ型結晶及びその製造方法
US5352387A (en) * 1992-11-25 1994-10-04 Lever Brothers Company Alkyl glyceramide surfactants and compositions comprising these surfactants
US5352386A (en) * 1992-11-25 1994-10-04 Lever Brothers Company Compositions free of boron comprising N-alkylerythronamides and N-alkylxylonamides as surfactants

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2904490A1 (de) * 1979-02-07 1980-08-21 Bayer Ag Verfahren zur herstellung von alpha -hydroxycarbonsaeureamiden
DE2944456C2 (de) * 1979-11-03 1982-04-01 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von N-α -Alkoxyalkyl-carbonsäureamiden
JPS57192347A (en) * 1981-05-18 1982-11-26 Microbial Chem Res Found N-(4-(3-aminopropyl)aminobutyl)-2,2-dihydroxyethanamide and its synthesis
GB2100253B (en) * 1981-05-11 1985-03-06 Microbial Chem Res Found N-(4-(3-aminopropyl)aminobutyl)-2,2-dihydroxyethanamide
JPS57185254A (en) * 1981-05-11 1982-11-15 Microbial Chem Res Found Novel carcinostatic substances and their preparation
JPS5862152A (ja) * 1981-10-08 1983-04-13 Microbial Chem Res Found Ｎ−〔４−（３−アミノプロピル）アミノブチル〕−２−（ω−グアニジノ脂肪酸アミド）−２−ヒドロキシエタンアミドおよびその誘導体ならびにその製造法
JPS5952263A (ja) * 1982-09-18 1984-03-26 Minolta Camera Co Ltd 静電潜像現像装置
US4448905A (en) * 1982-09-30 1984-05-15 Gaf Corporation Alcohol substituted amides as chain extenders for polyurethanes

Also Published As

Publication number Publication date
HUT36781A (en) 1985-10-28
JPH0350749B2 (ko) 1991-08-02
DE3506330C2 (ko) 1989-10-26
DK168762B1 (da) 1994-06-06
GB2155013A (en) 1985-09-18
AU564211B2 (en) 1987-08-06
JPS60181056A (ja) 1985-09-14
IT1208798B (it) 1989-07-10
DK86485A (da) 1985-08-30
HU193738B (en) 1987-11-30
ES540729A0 (es) 1986-10-16
ES8700652A1 (es) 1986-10-16
FR2563829A1 (fr) 1985-11-08
GB2155013B (en) 1988-04-27
AR240553A1 (es) 1990-05-31
DE3506330A1 (de) 1985-08-29
SE8500845D0 (sv) 1985-02-21
CH665635A5 (de) 1988-05-31
DK86485D0 (da) 1985-02-26
AU3914485A (en) 1985-09-05
CS139285A2 (en) 1989-08-14
CS268666B2 (en) 1990-04-11
SE8500845L (sv) 1985-08-30
US4603015A (en) 1986-07-29
FR2563829B1 (fr) 1988-10-14
CA1226004A (en) 1987-08-25
IT8567205A0 (it) 1985-02-27
GB8505049D0 (en) 1985-03-27
KR900001076B1 (ko) 1990-02-26
SE469130B (sv) 1993-05-17

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