KR840007439A - 폐염간군으로부터 추출한 면역-자극 아실당 단백질의 제조방법 - Google Patents

폐염간군으로부터 추출한 면역-자극 아실당 단백질의 제조방법 Download PDF

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Publication number
KR840007439A
KR840007439A KR1019840000357A KR840000357A KR840007439A KR 840007439 A KR840007439 A KR 840007439A KR 1019840000357 A KR1019840000357 A KR 1019840000357A KR 840000357 A KR840000357 A KR 840000357A KR 840007439 A KR840007439 A KR 840007439A
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South Korea
Prior art keywords
stimulating
ultrafilter
molecular weight
protein extracted
glycoprotein
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KR1019840000357A
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KR910009162B1 (ko
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스메쯔(외 1) 삐에르
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허버트 후리텔
로우셀 우크라프
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/26—Klebsiella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • A61K2039/55594—Adjuvants of undefined constitution from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

내용 없음.

Description

폐염간군으로부터 추출한 면역-자극 아실당 단백질의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (6)

  1. 폐염간균의 배양액의 분해물을 추출하여 투석여과함에 의해 얻어진 정제 당단백질 용액을 4급암모늄으로 처리하고 얻어진 침전물을 제거함에 의해 상청액을 분리하게 되는 당단백질의 제조방법에 있어 상기 공정은 그 상정액을, 분자들을 선택하기 위한 적어도 하나의 기구에 의해 농축시키고 농축물을 냉각시킬 때 적어도 하나의 저분자량의 알카놀로 처리하고 이렇게 얻어진 침전물을 분리하고 필요하다면 적어도 하나의 저분자량의 알칸올을 이용하여 세척하고 건조시킴을 특징으로 하는 당단백질의 제조방법.
  2. 상기 1항에 있어, 분자들의 선택을 위한 기구는 하나 또는 그 이상의 선택적 삼투막을 포함하는 상기의 방법.
  3. 상기 1 또는 2항에 있어, 분자들의 선택을 위한 기구는 하나 또는 그 이상의 한외여과기로 구성되는 상기의 방법.
  4. 상기 3항에 있어, 한외여과기는 5000 내지 100,000 달톤사이의 범위에서 분자량의 측정되는 절단역을 갖는 상기의 방법.
  5. 상기 3 또는 4항에 있어, 한외여과기는 속이 빈 섬유형태로 나타내는 상기의 방법.
  6. 상기 5항에 있어, 한외여과기는 폴리술포닌형이며, 5000달톤으로 측정되는 상기의 방법.
    ※ 참고사항:최초출원 내용에 의하여 공개하는 것임.
KR1019840000357A 1983-01-28 1984-01-27 폐염 간균으로부터 추출한 면역-자극아실당 단백질의 제조방법 KR910009162B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR8301345 1983-01-28
FR1345 1983-01-28
FR8301345A FR2540136A1 (fr) 1983-01-28 1983-01-28 Nouveau procede de preparation d'acylglycoproteines immunostimulantes extraites de klebsiella pneumoniae, compositions pharmaceutiques et procede de lutte contre les maladies allergiques

Publications (2)

Publication Number Publication Date
KR840007439A true KR840007439A (ko) 1984-12-07
KR910009162B1 KR910009162B1 (ko) 1991-10-31

Family

ID=9285393

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840000357A KR910009162B1 (ko) 1983-01-28 1984-01-27 폐염 간균으로부터 추출한 면역-자극아실당 단백질의 제조방법

Country Status (17)

Country Link
EP (1) EP0115988B1 (ko)
JP (1) JPS59141594A (ko)
KR (1) KR910009162B1 (ko)
AT (1) ATE22925T1 (ko)
AU (1) AU559247B2 (ko)
CA (1) CA1244405A (ko)
DE (1) DE3460982D1 (ko)
DK (1) DK37384A (ko)
ES (1) ES529224A0 (ko)
FI (1) FI78304C (ko)
FR (1) FR2540136A1 (ko)
HU (1) HU195538B (ko)
IE (1) IE56612B1 (ko)
IL (1) IL70731A (ko)
NZ (1) NZ206959A (ko)
PT (1) PT78012B (ko)
ZA (1) ZA84537B (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2574429B1 (fr) * 1984-12-06 1987-12-11 Roussel Uclaf Acylglycannes extraits de klebsiella, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant
FR2598434B1 (fr) * 1986-05-12 1988-09-16 Pf Medicament Nouveaux immunomodulateurs obtenus par hemisynthese a partir d'un polysaccharide bacterien isole d'une souche mutante non capsulee de klebsiella pneumoniae
FR2650506B1 (fr) * 1989-07-11 1991-11-08 Roussel Uclaf Galactanne extrait de klebsiella, procede d'obtention et application a titre de medicament
JP3662550B2 (ja) * 2002-05-08 2005-06-22 高砂香料工業株式会社 粉末組成物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2396019A1 (fr) * 1977-07-01 1979-01-26 Cassenne Lab Sa Nouveaux glycopeptides acetyles hydrosolubles extraits de corps microbiens lyses de pseudomonas aeruginosa, procede de preparation et application a titre de medicaments
FR2396020A1 (fr) * 1977-07-01 1979-01-26 Cassenne Lab Sa Nouveaux glycopeptides acetyles hydrosolubles extraits de corps microbiens lyses d'hafnia, d'aerobacter cloacae et de klebsiella pneumoniae, procede de preparation et application a titre de medicaments de ces produits
FR2444464A1 (fr) * 1978-12-19 1980-07-18 Fabre Sa Pierre Proteoglycanes bacteriens purifies, procede pour leur preparation et vaccin les contenant
FR2462477A1 (fr) * 1979-07-31 1981-02-13 Cassenne Lab Sa Nouvelles glycoproteines de klebsiella pneumoniae, procede d'obtention, application a titre de medicaments et compositions les renfermant
FR2490496A1 (fr) * 1980-09-19 1982-03-26 Roussel Uclaf Nouvelles glycoproteines immunostimulantes extraites de klebsiella pneumoniae, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant
FR2523154A1 (fr) * 1982-03-09 1983-09-16 Fabre Sa Pierre Procede de preparation de proteoglycanes immunostimulants inducteurs d'interferon, proteoglycanes obtenus et medicaments les contenant

Also Published As

Publication number Publication date
IE56612B1 (en) 1991-10-09
AU2386184A (en) 1984-08-02
ZA84537B (en) 1985-02-27
FI840351A0 (fi) 1984-01-27
DK37384A (da) 1984-07-29
KR910009162B1 (ko) 1991-10-31
AU559247B2 (en) 1987-03-05
NZ206959A (en) 1987-03-31
EP0115988A1 (fr) 1984-08-15
IE840186L (en) 1984-07-28
HU195538B (en) 1988-05-30
PT78012B (fr) 1986-06-18
ES8500326A1 (es) 1984-10-01
IL70731A (en) 1987-10-20
ATE22925T1 (de) 1986-11-15
FR2540136B1 (ko) 1985-05-03
FR2540136A1 (fr) 1984-08-03
FI78304B (fi) 1989-03-31
DE3460982D1 (en) 1986-11-20
DK37384D0 (da) 1984-01-27
FI78304C (fi) 1989-07-10
FI840351A (fi) 1984-07-29
CA1244405A (fr) 1988-11-08
IL70731A0 (en) 1984-04-30
JPS59141594A (ja) 1984-08-14
ES529224A0 (es) 1984-10-01
EP0115988B1 (fr) 1986-10-15
PT78012A (fr) 1984-02-01

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