ATE22925T1 - Verfahren zur gewinnung von aus klebsiella pneumoniae extrahierten immunostimulierenden acylproteinen, antiallergische pharmatzeutische zusammensetzungen. - Google Patents
Verfahren zur gewinnung von aus klebsiella pneumoniae extrahierten immunostimulierenden acylproteinen, antiallergische pharmatzeutische zusammensetzungen.Info
- Publication number
- ATE22925T1 ATE22925T1 AT84400172T AT84400172T ATE22925T1 AT E22925 T1 ATE22925 T1 AT E22925T1 AT 84400172 T AT84400172 T AT 84400172T AT 84400172 T AT84400172 T AT 84400172T AT E22925 T1 ATE22925 T1 AT E22925T1
- Authority
- AT
- Austria
- Prior art keywords
- klebsiella pneumoniae
- alkanol
- supernatant
- precipitate
- isolated
- Prior art date
Links
- 241000588747 Klebsiella pneumoniae Species 0.000 title abstract 3
- 230000003266 anti-allergic effect Effects 0.000 title 1
- 230000003308 immunostimulating effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 102000003886 Glycoproteins Human genes 0.000 abstract 4
- 108090000288 Glycoproteins Proteins 0.000 abstract 4
- 239000002244 precipitate Substances 0.000 abstract 4
- 239000006228 supernatant Substances 0.000 abstract 4
- 239000012141 concentrate Substances 0.000 abstract 2
- 150000004820 halides Chemical class 0.000 abstract 2
- 239000006166 lysate Substances 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 2
- 238000011026 diafiltration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/26—Klebsiella (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
- A61K2039/55594—Adjuvants of undefined constitution from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8301345A FR2540136A1 (fr) | 1983-01-28 | 1983-01-28 | Nouveau procede de preparation d'acylglycoproteines immunostimulantes extraites de klebsiella pneumoniae, compositions pharmaceutiques et procede de lutte contre les maladies allergiques |
| EP84400172A EP0115988B1 (de) | 1983-01-28 | 1984-01-26 | Verfahren zur Gewinnung von aus Klebsiella pneumoniae extrahierten immunostimulierenden Acylproteinen, antiallergische pharmatzeutische Zusammensetzungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE22925T1 true ATE22925T1 (de) | 1986-11-15 |
Family
ID=9285393
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT84400172T ATE22925T1 (de) | 1983-01-28 | 1984-01-26 | Verfahren zur gewinnung von aus klebsiella pneumoniae extrahierten immunostimulierenden acylproteinen, antiallergische pharmatzeutische zusammensetzungen. |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0115988B1 (de) |
| JP (1) | JPS59141594A (de) |
| KR (1) | KR910009162B1 (de) |
| AT (1) | ATE22925T1 (de) |
| AU (1) | AU559247B2 (de) |
| CA (1) | CA1244405A (de) |
| DE (1) | DE3460982D1 (de) |
| DK (1) | DK37384A (de) |
| ES (1) | ES529224A0 (de) |
| FI (1) | FI78304C (de) |
| FR (1) | FR2540136A1 (de) |
| HU (1) | HU195538B (de) |
| IE (1) | IE56612B1 (de) |
| IL (1) | IL70731A (de) |
| NZ (1) | NZ206959A (de) |
| PT (1) | PT78012B (de) |
| ZA (1) | ZA84537B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2574429B1 (fr) * | 1984-12-06 | 1987-12-11 | Roussel Uclaf | Acylglycannes extraits de klebsiella, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant |
| FR2598434B1 (fr) * | 1986-05-12 | 1988-09-16 | Pf Medicament | Nouveaux immunomodulateurs obtenus par hemisynthese a partir d'un polysaccharide bacterien isole d'une souche mutante non capsulee de klebsiella pneumoniae |
| FR2650506B1 (fr) * | 1989-07-11 | 1991-11-08 | Roussel Uclaf | Galactanne extrait de klebsiella, procede d'obtention et application a titre de medicament |
| JP3662550B2 (ja) * | 2002-05-08 | 2005-06-22 | 高砂香料工業株式会社 | 粉末組成物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2396019A1 (fr) * | 1977-07-01 | 1979-01-26 | Cassenne Lab Sa | Nouveaux glycopeptides acetyles hydrosolubles extraits de corps microbiens lyses de pseudomonas aeruginosa, procede de preparation et application a titre de medicaments |
| FR2396020A1 (fr) * | 1977-07-01 | 1979-01-26 | Cassenne Lab Sa | Nouveaux glycopeptides acetyles hydrosolubles extraits de corps microbiens lyses d'hafnia, d'aerobacter cloacae et de klebsiella pneumoniae, procede de preparation et application a titre de medicaments de ces produits |
| FR2444464A1 (fr) * | 1978-12-19 | 1980-07-18 | Fabre Sa Pierre | Proteoglycanes bacteriens purifies, procede pour leur preparation et vaccin les contenant |
| FR2462477A1 (fr) * | 1979-07-31 | 1981-02-13 | Cassenne Lab Sa | Nouvelles glycoproteines de klebsiella pneumoniae, procede d'obtention, application a titre de medicaments et compositions les renfermant |
| FR2490496A1 (fr) * | 1980-09-19 | 1982-03-26 | Roussel Uclaf | Nouvelles glycoproteines immunostimulantes extraites de klebsiella pneumoniae, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant |
| FR2523154A1 (fr) * | 1982-03-09 | 1983-09-16 | Fabre Sa Pierre | Procede de preparation de proteoglycanes immunostimulants inducteurs d'interferon, proteoglycanes obtenus et medicaments les contenant |
-
1983
- 1983-01-28 FR FR8301345A patent/FR2540136A1/fr active Granted
-
1984
- 1984-01-20 IL IL70731A patent/IL70731A/xx unknown
- 1984-01-24 ZA ZA84537A patent/ZA84537B/xx unknown
- 1984-01-26 AT AT84400172T patent/ATE22925T1/de not_active IP Right Cessation
- 1984-01-26 EP EP84400172A patent/EP0115988B1/de not_active Expired
- 1984-01-26 PT PT78012A patent/PT78012B/pt not_active IP Right Cessation
- 1984-01-26 DE DE8484400172T patent/DE3460982D1/de not_active Expired
- 1984-01-26 JP JP59011128A patent/JPS59141594A/ja active Pending
- 1984-01-27 IE IE186/84A patent/IE56612B1/en not_active IP Right Cessation
- 1984-01-27 ES ES529224A patent/ES529224A0/es active Granted
- 1984-01-27 CA CA000446183A patent/CA1244405A/fr not_active Expired
- 1984-01-27 HU HU84380A patent/HU195538B/hu not_active IP Right Cessation
- 1984-01-27 DK DK37384A patent/DK37384A/da not_active Application Discontinuation
- 1984-01-27 KR KR1019840000357A patent/KR910009162B1/ko not_active Expired
- 1984-01-27 AU AU23861/84A patent/AU559247B2/en not_active Ceased
- 1984-01-27 NZ NZ206959A patent/NZ206959A/en unknown
- 1984-01-27 FI FI840351A patent/FI78304C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR840007439A (ko) | 1984-12-07 |
| KR910009162B1 (ko) | 1991-10-31 |
| NZ206959A (en) | 1987-03-31 |
| FI78304B (fi) | 1989-03-31 |
| CA1244405A (fr) | 1988-11-08 |
| IL70731A0 (en) | 1984-04-30 |
| ZA84537B (en) | 1985-02-27 |
| PT78012A (fr) | 1984-02-01 |
| FI840351A0 (fi) | 1984-01-27 |
| HU195538B (en) | 1988-05-30 |
| AU2386184A (en) | 1984-08-02 |
| DK37384A (da) | 1984-07-29 |
| ES8500326A1 (es) | 1984-10-01 |
| IL70731A (en) | 1987-10-20 |
| PT78012B (fr) | 1986-06-18 |
| EP0115988A1 (de) | 1984-08-15 |
| JPS59141594A (ja) | 1984-08-14 |
| AU559247B2 (en) | 1987-03-05 |
| FI840351L (fi) | 1984-07-29 |
| FI78304C (fi) | 1989-07-10 |
| DE3460982D1 (en) | 1986-11-20 |
| FR2540136A1 (fr) | 1984-08-03 |
| FR2540136B1 (de) | 1985-05-03 |
| EP0115988B1 (de) | 1986-10-15 |
| IE840186L (en) | 1984-07-28 |
| DK37384D0 (da) | 1984-01-27 |
| IE56612B1 (en) | 1991-10-09 |
| ES529224A0 (es) | 1984-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |