ZA84537B - Preparation process for immuno-stimulating acyglycoproteins extracted from klebsiella pneumoniae,anti-allergic pharmaceutical compositions and method of treatment of allergic diseases - Google Patents

Preparation process for immuno-stimulating acyglycoproteins extracted from klebsiella pneumoniae,anti-allergic pharmaceutical compositions and method of treatment of allergic diseases

Info

Publication number
ZA84537B
ZA84537B ZA84537A ZA84537A ZA84537B ZA 84537 B ZA84537 B ZA 84537B ZA 84537 A ZA84537 A ZA 84537A ZA 84537 A ZA84537 A ZA 84537A ZA 84537 B ZA84537 B ZA 84537B
Authority
ZA
South Africa
Prior art keywords
preparation process
allergic
klebsiella pneumoniae
acyglycoproteins
immuno
Prior art date
Application number
ZA84537A
Inventor
Pierre Smets
Rene Zalisz
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA84537B publication Critical patent/ZA84537B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/26—Klebsiella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • A61K2039/55594—Adjuvants of undefined constitution from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

For the Contracting States BE CH DE GB IT LI LU NL SE 1. Preparation process for glycoproteins in which, in order, a solution of purified glycoproteins is prepared by diafiltration of an extract of a lysate of cultures of Klebsiella pneumoniae, the said solution is treated with a halide of a quaternary ammonium, the supernatant is isolated by eliminating the precipitate so obtined, the supernatant is concentrated by use of at least one means of selection of molecules, the concentrate is treated cold with at least one alkanol of low molecular weight, the precipitate so obtained is isolated and, if desired, is washed with at least one alkanol of low molecular weight and dried. For the Contracting State AT 1. Preparation process for glycoproteins in which, in order, a solution of purified glycoproteins is prepared by dialfiltration of an extract of a lysate of cultures of Klebsiella pneumoniae, the said solution is treated with a halide of a quaternary ammonium, the supernatant is isolated by eliminating the precipitate so obtained, the supernatant is concentrated by use of at least one means of selection of molelules, the concentrate is treated cold with at least one alkanol of low molecular weight, the precipitate so obtained is isolated and, if desired, is washed with at least one alkanol of low molecular weight and dried.
ZA84537A 1983-01-28 1984-01-24 Preparation process for immuno-stimulating acyglycoproteins extracted from klebsiella pneumoniae,anti-allergic pharmaceutical compositions and method of treatment of allergic diseases ZA84537B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8301345A FR2540136A1 (en) 1983-01-28 1983-01-28 NOVEL PROCESS FOR THE PREPARATION OF IMMUNOSTIMULATING ACYLGLYCOPROTEINS EXTRACTED FROM KLEBSIELLA PNEUMONIAE, PHARMACEUTICAL COMPOSITIONS AND METHOD FOR CONTROLLING ALLERGIC DISEASES

Publications (1)

Publication Number Publication Date
ZA84537B true ZA84537B (en) 1985-02-27

Family

ID=9285393

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA84537A ZA84537B (en) 1983-01-28 1984-01-24 Preparation process for immuno-stimulating acyglycoproteins extracted from klebsiella pneumoniae,anti-allergic pharmaceutical compositions and method of treatment of allergic diseases

Country Status (17)

Country Link
EP (1) EP0115988B1 (en)
JP (1) JPS59141594A (en)
KR (1) KR910009162B1 (en)
AT (1) ATE22925T1 (en)
AU (1) AU559247B2 (en)
CA (1) CA1244405A (en)
DE (1) DE3460982D1 (en)
DK (1) DK37384A (en)
ES (1) ES8500326A1 (en)
FI (1) FI78304C (en)
FR (1) FR2540136A1 (en)
HU (1) HU195538B (en)
IE (1) IE56612B1 (en)
IL (1) IL70731A (en)
NZ (1) NZ206959A (en)
PT (1) PT78012B (en)
ZA (1) ZA84537B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2574429B1 (en) * 1984-12-06 1987-12-11 Roussel Uclaf ACYLGLYCANNES EXTRACTED FROM KLEBSIELLA, PROCESS FOR OBTAINING THEM, THEIR APPLICATION AS MEDICAMENTS AND THE COMPOSITIONS CONTAINING THEM
FR2598434B1 (en) * 1986-05-12 1988-09-16 Pf Medicament NEW IMMUNOMODULATORS OBTAINED BY HEMISYNTHESIS FROM A BACTERIAL POLYSACCHARIDE ISOLATED FROM AN UNCAPSULATED MUTANT STRAIN OF KLEBSIELLA PNEUMONIAE
FR2650506B1 (en) * 1989-07-11 1991-11-08 Roussel Uclaf GALACTANNE EXTRACT OF KLEBSIELLA, PROCESS FOR OBTAINING AND APPLICATION AS A MEDICAMENT
JP3662550B2 (en) * 2002-05-08 2005-06-22 高砂香料工業株式会社 Powder composition

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2396019A1 (en) * 1977-07-01 1979-01-26 Cassenne Lab Sa Acetylated water soluble gluco-peptide prepn. - from pseudomonas aeruginosa; used as antiinflammatories, antibacterials, and immunostimulant(s)
FR2396020A1 (en) * 1977-07-01 1979-01-26 Cassenne Lab Sa Acetylated water soluble gluco-peptide prepn. - from Hafnia, Aerobacter cloacae or Klebsiella pneumoniae, used as antiinflammatories and immunostimulant(s)
FR2444464A1 (en) * 1978-12-19 1980-07-18 Fabre Sa Pierre PURIFIED BACTERIAL PROTEOGLYCANS, PROCESS FOR THEIR PREPARATION AND VACCINE CONTAINING THEM
FR2462477A1 (en) * 1979-07-31 1981-02-13 Cassenne Lab Sa NOVEL KLEBSIELLA PNEUMONIAE GLYCOPROTEINS, PROCESS FOR OBTAINING THEM, APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM
FR2490496A1 (en) * 1980-09-19 1982-03-26 Roussel Uclaf NEW IMMUNOSTIMULANT GLYCOPROTEINS EXTRACTED FROM KLEBSIELLA PNEUMONIAE, PROCESS FOR OBTAINING THEM, THEIR APPLICATION AS MEDICAMENTS AND COMPOSITIONS COMPRISING THE SAME
FR2523154A1 (en) * 1982-03-09 1983-09-16 Fabre Sa Pierre PROCESS FOR THE PREPARATION OF INTERFERON-INDUCING IMMUNOSTIMULATING PROTEOGLYCANS, PROTEOGLYCANS OBTAINED AND MEDICAMENTS CONTAINING THEM

Also Published As

Publication number Publication date
DK37384A (en) 1984-07-29
KR840007439A (en) 1984-12-07
IE840186L (en) 1984-07-28
HU195538B (en) 1988-05-30
KR910009162B1 (en) 1991-10-31
EP0115988A1 (en) 1984-08-15
FR2540136B1 (en) 1985-05-03
IL70731A0 (en) 1984-04-30
AU559247B2 (en) 1987-03-05
FR2540136A1 (en) 1984-08-03
FI78304B (en) 1989-03-31
EP0115988B1 (en) 1986-10-15
DE3460982D1 (en) 1986-11-20
AU2386184A (en) 1984-08-02
IE56612B1 (en) 1991-10-09
PT78012B (en) 1986-06-18
FI840351A0 (en) 1984-01-27
ATE22925T1 (en) 1986-11-15
ES529224A0 (en) 1984-10-01
NZ206959A (en) 1987-03-31
FI78304C (en) 1989-07-10
ES8500326A1 (en) 1984-10-01
IL70731A (en) 1987-10-20
CA1244405A (en) 1988-11-08
FI840351A (en) 1984-07-29
DK37384D0 (en) 1984-01-27
PT78012A (en) 1984-02-01
JPS59141594A (en) 1984-08-14

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