FI840351A - NYTT FOERFARANDE FOER FRAMSTAELLNING AV KLEBSIELLA PNEUMONIA EXTRAHERADE IMMUNSYSTEMET STIMULERANDE ACYLGLYKOPROTEINER. - Google Patents

NYTT FOERFARANDE FOER FRAMSTAELLNING AV KLEBSIELLA PNEUMONIA EXTRAHERADE IMMUNSYSTEMET STIMULERANDE ACYLGLYKOPROTEINER. Download PDF

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Publication number
FI840351A
FI840351A FI840351A FI840351A FI840351A FI 840351 A FI840351 A FI 840351A FI 840351 A FI840351 A FI 840351A FI 840351 A FI840351 A FI 840351A FI 840351 A FI840351 A FI 840351A
Authority
FI
Finland
Prior art keywords
stimulerande
immunsystemet
extraherade
acylglykoproteiner
alkanol
Prior art date
Application number
FI840351A
Other languages
Finnish (fi)
Other versions
FI78304B (en
FI78304C (en
FI840351A0 (en
Inventor
Pierre Smets
Rene Zalisz
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of FI840351A0 publication Critical patent/FI840351A0/en
Publication of FI840351A publication Critical patent/FI840351A/en
Publication of FI78304B publication Critical patent/FI78304B/en
Application granted granted Critical
Publication of FI78304C publication Critical patent/FI78304C/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/26Klebsiella (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55516Proteins; Peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588Adjuvants of undefined constitution
    • A61K2039/55594Adjuvants of undefined constitution from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

For the Contracting States BE CH DE GB IT LI LU NL SE 1. Preparation process for glycoproteins in which, in order, a solution of purified glycoproteins is prepared by diafiltration of an extract of a lysate of cultures of Klebsiella pneumoniae, the said solution is treated with a halide of a quaternary ammonium, the supernatant is isolated by eliminating the precipitate so obtined, the supernatant is concentrated by use of at least one means of selection of molecules, the concentrate is treated cold with at least one alkanol of low molecular weight, the precipitate so obtained is isolated and, if desired, is washed with at least one alkanol of low molecular weight and dried. For the Contracting State AT 1. Preparation process for glycoproteins in which, in order, a solution of purified glycoproteins is prepared by dialfiltration of an extract of a lysate of cultures of Klebsiella pneumoniae, the said solution is treated with a halide of a quaternary ammonium, the supernatant is isolated by eliminating the precipitate so obtained, the supernatant is concentrated by use of at least one means of selection of molelules, the concentrate is treated cold with at least one alkanol of low molecular weight, the precipitate so obtained is isolated and, if desired, is washed with at least one alkanol of low molecular weight and dried.
FI840351A 1983-01-28 1984-01-27 New Procedure for the Production of Klebsiella Pneumonia Extracted Immune System Stimulating Acyl Glycoproteins FI78304C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8301345A FR2540136A1 (en) 1983-01-28 1983-01-28 NOVEL PROCESS FOR THE PREPARATION OF IMMUNOSTIMULATING ACYLGLYCOPROTEINS EXTRACTED FROM KLEBSIELLA PNEUMONIAE, PHARMACEUTICAL COMPOSITIONS AND METHOD FOR CONTROLLING ALLERGIC DISEASES
FR8301345 1983-01-28

Publications (4)

Publication Number Publication Date
FI840351A0 FI840351A0 (en) 1984-01-27
FI840351A true FI840351A (en) 1984-07-29
FI78304B FI78304B (en) 1989-03-31
FI78304C FI78304C (en) 1989-07-10

Family

ID=9285393

Family Applications (1)

Application Number Title Priority Date Filing Date
FI840351A FI78304C (en) 1983-01-28 1984-01-27 New Procedure for the Production of Klebsiella Pneumonia Extracted Immune System Stimulating Acyl Glycoproteins

Country Status (17)

Country Link
EP (1) EP0115988B1 (en)
JP (1) JPS59141594A (en)
KR (1) KR910009162B1 (en)
AT (1) ATE22925T1 (en)
AU (1) AU559247B2 (en)
CA (1) CA1244405A (en)
DE (1) DE3460982D1 (en)
DK (1) DK37384A (en)
ES (1) ES8500326A1 (en)
FI (1) FI78304C (en)
FR (1) FR2540136A1 (en)
HU (1) HU195538B (en)
IE (1) IE56612B1 (en)
IL (1) IL70731A (en)
NZ (1) NZ206959A (en)
PT (1) PT78012B (en)
ZA (1) ZA84537B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2574429B1 (en) * 1984-12-06 1987-12-11 Roussel Uclaf ACYLGLYCANNES EXTRACTED FROM KLEBSIELLA, PROCESS FOR OBTAINING THEM, THEIR APPLICATION AS MEDICAMENTS AND THE COMPOSITIONS CONTAINING THEM
FR2598434B1 (en) * 1986-05-12 1988-09-16 Pf Medicament NEW IMMUNOMODULATORS OBTAINED BY HEMISYNTHESIS FROM A BACTERIAL POLYSACCHARIDE ISOLATED FROM AN UNCAPSULATED MUTANT STRAIN OF KLEBSIELLA PNEUMONIAE
FR2650506B1 (en) * 1989-07-11 1991-11-08 Roussel Uclaf GALACTANNE EXTRACT OF KLEBSIELLA, PROCESS FOR OBTAINING AND APPLICATION AS A MEDICAMENT
JP3662550B2 (en) * 2002-05-08 2005-06-22 高砂香料工業株式会社 Powder composition

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2396020A1 (en) * 1977-07-01 1979-01-26 Cassenne Lab Sa Acetylated water soluble gluco-peptide prepn. - from Hafnia, Aerobacter cloacae or Klebsiella pneumoniae, used as antiinflammatories and immunostimulant(s)
FR2396019A1 (en) * 1977-07-01 1979-01-26 Cassenne Lab Sa Acetylated water soluble gluco-peptide prepn. - from pseudomonas aeruginosa; used as antiinflammatories, antibacterials, and immunostimulant(s)
FR2444464A1 (en) * 1978-12-19 1980-07-18 Fabre Sa Pierre PURIFIED BACTERIAL PROTEOGLYCANS, PROCESS FOR THEIR PREPARATION AND VACCINE CONTAINING THEM
FR2462477A1 (en) * 1979-07-31 1981-02-13 Cassenne Lab Sa NOVEL KLEBSIELLA PNEUMONIAE GLYCOPROTEINS, PROCESS FOR OBTAINING THEM, APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM
FR2490496A1 (en) * 1980-09-19 1982-03-26 Roussel Uclaf NEW IMMUNOSTIMULANT GLYCOPROTEINS EXTRACTED FROM KLEBSIELLA PNEUMONIAE, PROCESS FOR OBTAINING THEM, THEIR APPLICATION AS MEDICAMENTS AND COMPOSITIONS COMPRISING THE SAME
FR2523154A1 (en) * 1982-03-09 1983-09-16 Fabre Sa Pierre PROCESS FOR THE PREPARATION OF INTERFERON-INDUCING IMMUNOSTIMULATING PROTEOGLYCANS, PROTEOGLYCANS OBTAINED AND MEDICAMENTS CONTAINING THEM

Also Published As

Publication number Publication date
DK37384D0 (en) 1984-01-27
FI78304B (en) 1989-03-31
IL70731A0 (en) 1984-04-30
JPS59141594A (en) 1984-08-14
IE840186L (en) 1984-07-28
DE3460982D1 (en) 1986-11-20
IE56612B1 (en) 1991-10-09
HU195538B (en) 1988-05-30
EP0115988A1 (en) 1984-08-15
ATE22925T1 (en) 1986-11-15
PT78012B (en) 1986-06-18
KR840007439A (en) 1984-12-07
ES529224A0 (en) 1984-10-01
NZ206959A (en) 1987-03-31
FR2540136B1 (en) 1985-05-03
AU2386184A (en) 1984-08-02
AU559247B2 (en) 1987-03-05
FI78304C (en) 1989-07-10
EP0115988B1 (en) 1986-10-15
ZA84537B (en) 1985-02-27
ES8500326A1 (en) 1984-10-01
IL70731A (en) 1987-10-20
KR910009162B1 (en) 1991-10-31
FI840351A0 (en) 1984-01-27
DK37384A (en) 1984-07-29
CA1244405A (en) 1988-11-08
FR2540136A1 (en) 1984-08-03
PT78012A (en) 1984-02-01

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MM Patent lapsed
MM Patent lapsed

Owner name: ROUSSEL UCLAF SOCIETE ANONYME