KR840006984A - 새로운 약학적 화합물 및 이의 제조방법 - Google Patents
새로운 약학적 화합물 및 이의 제조방법 Download PDFInfo
- Publication number
- KR840006984A KR840006984A KR1019830005696A KR830005696A KR840006984A KR 840006984 A KR840006984 A KR 840006984A KR 1019830005696 A KR1019830005696 A KR 1019830005696A KR 830005696 A KR830005696 A KR 830005696A KR 840006984 A KR840006984 A KR 840006984A
- Authority
- KR
- South Korea
- Prior art keywords
- hydrogen
- alkyl
- alkoxy
- compound
- carboxyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001875 compounds Chemical class 0.000 title claims 14
- 238000002360 preparation method Methods 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 16
- 239000001257 hydrogen Substances 0.000 claims 16
- 125000000217 alkyl group Chemical group 0.000 claims 12
- -1 cyano, hydroxy Chemical group 0.000 claims 12
- 150000002431 hydrogen Chemical class 0.000 claims 12
- 125000003545 alkoxy group Chemical group 0.000 claims 10
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 9
- 125000003342 alkenyl group Chemical group 0.000 claims 7
- 229910052736 halogen Inorganic materials 0.000 claims 6
- 150000002367 halogens Chemical class 0.000 claims 6
- 125000004299 tetrazol-5-yl group Chemical group [H]N1N=NC(*)=N1 0.000 claims 6
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 4
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 claims 3
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims 3
- 125000004442 acylamino group Chemical group 0.000 claims 3
- 125000003302 alkenyloxy group Chemical group 0.000 claims 3
- 125000004457 alkyl amino carbonyl group Chemical group 0.000 claims 3
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 3
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 150000001721 carbon Chemical group 0.000 claims 2
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 2
- 150000002148 esters Chemical class 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8234671 | 1982-12-04 | ||
| GB8234670 | 1982-12-04 | ||
| GB8234670 | 1982-12-04 | ||
| GB8234671 | 1982-12-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR840006984A true KR840006984A (ko) | 1984-12-04 |
Family
ID=26284599
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019830005696A Withdrawn KR840006984A (ko) | 1982-12-04 | 1983-12-01 | 새로운 약학적 화합물 및 이의 제조방법 |
Country Status (9)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5026759A (en) * | 1985-05-08 | 1991-06-25 | Du Pont Merck Pharmaceutical | 2-substituted-1-naphthols as 5-lipoxygenase inhibitors |
| SU1600627A3 (ru) * | 1985-05-08 | 1990-10-15 | Е.И.Дюпон Де Немур Энд Компани (Фирма) | Способ получени 2-замещенных 1-нафтолов |
| US5656661A (en) * | 1994-07-27 | 1997-08-12 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| ATE385496T1 (de) * | 1994-07-27 | 2008-02-15 | Univ Vanderbilt | Dihydrobenzofurane und verwandte verbindungen als entzündungshemmende mittel |
| US5672620A (en) * | 1996-02-01 | 1997-09-30 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| US5684031A (en) * | 1996-02-01 | 1997-11-04 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| DE50104383D1 (de) * | 2000-01-28 | 2004-12-09 | Merck Patent Gmbh | Benzofuranonderivate enthaltende formulierung zum schutz vor oxidativem stress |
| TWI582112B (zh) | 2011-04-21 | 2017-05-11 | 西雅圖遺傳學公司 | 新穎結合劑－藥物接合物（ＡＤＣｓ）及其用途（二） |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3627763A (en) * | 1969-09-02 | 1971-12-14 | Knut A Jaeggi | Substituted 2-benzyl-benzofuran derivatives |
| US4259340A (en) * | 1978-09-13 | 1981-03-31 | Lilly Industries Limited | Aurone derivatives |
-
1983
- 1983-11-28 HU HU834078A patent/HUT36107A/hu unknown
- 1983-11-28 GR GR73092A patent/GR81257B/el unknown
- 1983-11-29 IL IL70346A patent/IL70346A0/xx unknown
- 1983-12-01 KR KR1019830005696A patent/KR840006984A/ko not_active Withdrawn
- 1983-12-01 IE IE2830/83A patent/IE56364B1/xx unknown
- 1983-12-02 EP EP83307350A patent/EP0113534A1/en not_active Withdrawn
- 1983-12-02 CA CA000442440A patent/CA1212678A/en not_active Expired
- 1983-12-02 GB GB08332269A patent/GB2131431B/en not_active Expired
- 1983-12-02 DK DK556483A patent/DK556483A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| GB2131431A (en) | 1984-06-20 |
| EP0113534A1 (en) | 1984-07-18 |
| GB8332269D0 (en) | 1984-01-11 |
| CA1212678A (en) | 1986-10-14 |
| IE832830L (en) | 1984-06-04 |
| HUT36107A (en) | 1985-08-28 |
| GB2131431B (en) | 1986-07-02 |
| DK556483A (da) | 1984-06-05 |
| IE56364B1 (en) | 1991-07-03 |
| DK556483D0 (da) | 1983-12-02 |
| IL70346A0 (en) | 1984-02-29 |
| GR81257B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-12-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19831201 |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |