KR840006334A - 설파모일 벤조페논 유도체의 제조방법 - Google Patents
설파모일 벤조페논 유도체의 제조방법 Download PDFInfo
- Publication number
- KR840006334A KR840006334A KR1019830004127A KR830004127A KR840006334A KR 840006334 A KR840006334 A KR 840006334A KR 1019830004127 A KR1019830004127 A KR 1019830004127A KR 830004127 A KR830004127 A KR 830004127A KR 840006334 A KR840006334 A KR 840006334A
- Authority
- KR
- South Korea
- Prior art keywords
- hydrogen
- formula
- alkyl
- compound
- hydrogen atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- TUGNLJZTKXCQMO-UHFFFAOYSA-N 2-benzoylbenzenesulfonamide Chemical class NS(=O)(=O)C1=CC=CC=C1C(=O)C1=CC=CC=C1 TUGNLJZTKXCQMO-UHFFFAOYSA-N 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 16
- 239000001257 hydrogen Substances 0.000 claims 16
- 150000001875 compounds Chemical class 0.000 claims 14
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 8
- 150000002431 hydrogen Chemical class 0.000 claims 8
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 8
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 5
- 125000006239 protecting group Chemical group 0.000 claims 4
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 2
- 239000003513 alkali Substances 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 229910052801 chlorine Inorganic materials 0.000 claims 2
- 239000000460 chlorine Substances 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- 150000002989 phenols Chemical class 0.000 claims 2
- 150000001242 acetic acid derivatives Chemical class 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 238000005903 acid hydrolysis reaction Methods 0.000 claims 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims 1
- 230000029936 alkylation Effects 0.000 claims 1
- 238000005804 alkylation reaction Methods 0.000 claims 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims 1
- 230000009977 dual effect Effects 0.000 claims 1
- 230000032050 esterification Effects 0.000 claims 1
- 238000005886 esterification reaction Methods 0.000 claims 1
- 230000007062 hydrolysis Effects 0.000 claims 1
- 238000006460 hydrolysis reaction Methods 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- -1 methylenedi Oxy Chemical class 0.000 claims 1
- 230000000269 nucleophilic effect Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 125000000565 sulfonamide group Chemical group 0.000 claims 1
- 231100000331 toxic Toxicity 0.000 claims 1
- 230000002588 toxic effect Effects 0.000 claims 1
- 238000005809 transesterification reaction Methods 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
- C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/06—One of the condensed rings being a six-membered aromatic ring the other ring being four-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823232922 DE3232922A1 (de) | 1982-09-04 | 1982-09-04 | Sulfamoylbenzophenon-derivate, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen |
| DEP32329229 | 1982-09-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR840006334A true KR840006334A (ko) | 1984-11-29 |
Family
ID=6172480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019830004127A Withdrawn KR840006334A (ko) | 1982-09-04 | 1983-09-02 | 설파모일 벤조페논 유도체의 제조방법 |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0104483A3 (cg-RX-API-DMAC7.html) |
| JP (1) | JPS5973563A (cg-RX-API-DMAC7.html) |
| KR (1) | KR840006334A (cg-RX-API-DMAC7.html) |
| AU (1) | AU1867883A (cg-RX-API-DMAC7.html) |
| DE (1) | DE3232922A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK402083A (cg-RX-API-DMAC7.html) |
| ES (1) | ES8500054A1 (cg-RX-API-DMAC7.html) |
| FI (1) | FI833118A7 (cg-RX-API-DMAC7.html) |
| GR (1) | GR78942B (cg-RX-API-DMAC7.html) |
| IL (1) | IL69641A0 (cg-RX-API-DMAC7.html) |
| MA (1) | MA19893A1 (cg-RX-API-DMAC7.html) |
| NO (1) | NO833157L (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ205469A (cg-RX-API-DMAC7.html) |
| PT (1) | PT77286B (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA836512B (cg-RX-API-DMAC7.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3317884A1 (de) * | 1983-05-17 | 1984-11-22 | Hoechst Ag, 6230 Frankfurt | 5-(4-chlor-3-sulfamoylbenzoyl)-2,3-dihydro-2-benzofurancarbonsaeuren und verfahren zu ihrer herstellung |
| EP1317258B1 (en) * | 2000-06-28 | 2009-02-11 | Merck & Co., Inc. | Use of allopurinol for the treatment of hypertension |
| WO2006121995A2 (en) | 2005-05-09 | 2006-11-16 | Tap Pharmaceutical Products, Inc. | Methods for treating nephrolithiasis |
| JP5978216B2 (ja) | 2010-09-10 | 2016-08-24 | タケダ ファーマシューティカルズ ユー．エス．エー． インコーポレイティド | テオフィリンとフェブキソスタットの併用療法のための方法 |
| JP5363636B2 (ja) * | 2011-10-21 | 2013-12-11 | ファイザー・リミテッド | 新規な塩および医学的使用 |
| TW201512171A (zh) | 2013-04-19 | 2015-04-01 | Pfizer Ltd | 化學化合物 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1129478B (de) * | 1957-11-04 | 1962-05-17 | Geigy Ag J R | Verfahren zur Herstellung von Benzophenonsulfonamiden |
-
1982
- 1982-09-04 DE DE19823232922 patent/DE3232922A1/de not_active Withdrawn
-
1983
- 1983-08-31 EP EP83108577A patent/EP0104483A3/de not_active Withdrawn
- 1983-09-01 FI FI833118A patent/FI833118A7/fi not_active Application Discontinuation
- 1983-09-02 NZ NZ205469A patent/NZ205469A/en unknown
- 1983-09-02 ZA ZA836512A patent/ZA836512B/xx unknown
- 1983-09-02 JP JP58160601A patent/JPS5973563A/ja active Pending
- 1983-09-02 ES ES525333A patent/ES8500054A1/es not_active Expired
- 1983-09-02 AU AU18678/83A patent/AU1867883A/en not_active Abandoned
- 1983-09-02 PT PT77286A patent/PT77286B/pt unknown
- 1983-09-02 GR GR72362A patent/GR78942B/el unknown
- 1983-09-02 DK DK402083A patent/DK402083A/da not_active Application Discontinuation
- 1983-09-02 NO NO833157A patent/NO833157L/no unknown
- 1983-09-02 IL IL69641A patent/IL69641A0/xx unknown
- 1983-09-02 KR KR1019830004127A patent/KR840006334A/ko not_active Withdrawn
- 1983-09-03 MA MA20116A patent/MA19893A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5973563A (ja) | 1984-04-25 |
| NZ205469A (en) | 1986-04-11 |
| EP0104483A3 (de) | 1984-08-15 |
| PT77286A (fr) | 1983-10-01 |
| FI833118A7 (fi) | 1984-03-05 |
| IL69641A0 (en) | 1983-12-30 |
| ES525333A0 (es) | 1984-10-01 |
| FI833118A0 (fi) | 1983-09-01 |
| ZA836512B (en) | 1985-03-27 |
| GR78942B (cg-RX-API-DMAC7.html) | 1984-10-02 |
| DE3232922A1 (de) | 1984-03-08 |
| EP0104483A2 (de) | 1984-04-04 |
| ES8500054A1 (es) | 1984-10-01 |
| DK402083D0 (da) | 1983-09-02 |
| NO833157L (no) | 1984-03-05 |
| DK402083A (da) | 1984-03-05 |
| PT77286B (fr) | 1986-04-09 |
| AU1867883A (en) | 1984-03-08 |
| MA19893A1 (fr) | 1984-04-01 |
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| FI823732L (fi) | Nya 1-furyl-3,4-dihydroisokinoliner, laekemedel innehaollande dessa samt deras framstaellningsfoerfaranden och deras anvaendning |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19830902 |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |