KR840004405A - 축합된 피롤리논 유도체의 제조방법 - Google Patents

축합된 피롤리논 유도체의 제조방법 Download PDF

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KR840004405A
KR840004405A KR1019830001350A KR830001350A KR840004405A KR 840004405 A KR840004405 A KR 840004405A KR 1019830001350 A KR1019830001350 A KR 1019830001350A KR 830001350 A KR830001350 A KR 830001350A KR 840004405 A KR840004405 A KR 840004405A
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integer
formula
optionally substituted
amidated
esterified
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KR1019830001350A
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KR900007780B1 (ko
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겐따로(외 1) 히라가
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구라바야시 이꾸시로
다께다야꾸힝고오교 가부시기 가이샤
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Priority claimed from PCT/JP1982/000096 external-priority patent/WO1983003410A1/ja
Priority claimed from PCT/JP1982/000401 external-priority patent/WO1984001576A1/ja
Priority claimed from PCT/JP1983/000032 external-priority patent/WO1984003089A1/ja
Application filed by 구라바야시 이꾸시로, 다께다야꾸힝고오교 가부시기 가이샤 filed Critical 구라바야시 이꾸시로
Publication of KR840004405A publication Critical patent/KR840004405A/ko
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Publication of KR900007780B1 publication Critical patent/KR900007780B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5532—Seven-(or more) membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/59—Hydrogenated pyridine rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

내용 없음

Description

축합된 피롤리논 유도체의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 일반식(Ⅱ)의 화합물을 가수분해 및 필요하다면 생성된 가수분해 화합물을 에스테르화 또는 아미드화함을 특징으로 하는 일반식(Ⅰ)의 화합물 및 그의 염의 제조방법
    상기 식에서 X는 임의 치환돌수 있는 시클릭기이고, Y는 임으로 에스테르화 또는 아미드화될 수 있는 카르복실기이며, Z는 -CH=CH-CH=CH-, -S-(CH2)1-S-(1은 1-3의 정수), -N=CH=CH-CH=N- 또는 -(CH2)m-(m)은 3-5의 정수)이고, 환A는 할로겐, 니트로, 아미노, 알파노일아미노, 알콕시카르보닐, 카르복실 또는 카르바모일에 의해 임의 치환될 수 있으며, n은 1-3의 정수이고 Q는 -COOR4(R4는 저급 알킬) 또는 -CN이다.
  2. 일반식(Ⅲ)의 화합물을 일반식 Ph3P=CHY의 화합물과 반응시킴을 특징으로 하는 일반식(Ⅰ)의 화합물 및 그의 염의 제조방법
    상기 식에서 X는 임의로 치환돌 수 있는 시클릭기이고, Y는 임의로 에스테르화 또는 아미드화될 수 있는 카르복실기이며, Z는 -CH=CH-CH=CH-, -S-(CH2)1-S-(1은 1-3의 정수), -N=CH=CH-CH=N- 또는 -(CH2)m-(m은 3-5의 정수)이고, 환A는 할로겐, 니트로, 아미노, 알파노일아미노, 알콕시카르보닐, 카르복실 또는 카르바모일에 의해 임의 치환될 수 있으며, n은 1이다.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019830001350A 1982-04-02 1983-04-01 축합된 피롤리논 유도체의 제조방법 KR900007780B1 (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
JPPCT/JP82/00096 1982-04-02
JPPCT/JP82/96 1982-04-02
PCT/JP1982/000096 WO1983003410A1 (en) 1982-04-02 1982-04-02 Isoindolin derivatives
JPPCT/JP82/00401 1982-10-07
JPPCT/JP82/401 1982-10-07
PCT/JP1982/000401 WO1984001576A1 (en) 1982-10-07 1982-10-07 Fused pyrrolinone derivatives
PCT/JP1983/000032 WO1984003089A1 (en) 1983-02-05 1983-02-05 Condensed pyrrolinone derivatives
JPPCT/JP83/32 1983-02-05
JPPCT/JP83/00032 1983-02-05

Publications (2)

Publication Number Publication Date
KR840004405A true KR840004405A (ko) 1984-10-15
KR900007780B1 KR900007780B1 (ko) 1990-10-20

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KR1019830001350A KR900007780B1 (ko) 1982-04-02 1983-04-01 축합된 피롤리논 유도체의 제조방법

Country Status (7)

Country Link
US (3) US4590189A (ko)
EP (1) EP0091241B1 (ko)
KR (1) KR900007780B1 (ko)
AT (1) ATE39483T1 (ko)
CA (1) CA1196330A (ko)
DE (1) DE3378763D1 (ko)
HK (1) HK104190A (ko)

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Also Published As

Publication number Publication date
US4590189A (en) 1986-05-20
DE3378763D1 (en) 1989-02-02
KR900007780B1 (ko) 1990-10-20
ATE39483T1 (de) 1989-01-15
EP0091241A3 (en) 1984-07-11
CA1196330A (en) 1985-11-05
US4788191A (en) 1988-11-29
HK104190A (en) 1990-12-21
US4879293A (en) 1989-11-07
EP0091241B1 (en) 1988-12-28
EP0091241A2 (en) 1983-10-12

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